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Background: Monte Carlo simulations of diffusion are commonly used as a model validation tool as they are especially suitable for generating the diffusion MRI signal in complicated tissue microgeometries. New method: Here we describe the…

Medical Physics · Physics 2021-04-13 Hong-Hsi Lee , Els Fieremans , Dmitry S Novikov

Endoluminal surgery offers a minimally invasive option for early-stage gastrointestinal and urinary tract cancers but is limited by surgical tools and a steep learning curve. Robotic systems, particularly continuum robots, provide flexible…

Cell detection is an essential task in cell image analysis. Recent deep learning-based detection methods have achieved very promising results. In general, these methods require exhaustively annotating the cells in an entire image. If some…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Kazuma Fujii , Daiki Suehiro , Kazuya Nishimura , Ryoma Bise

Deep learning is ubiquitous, but its lack of transparency limits its impact on several potential application areas. We demonstrate a virtual reality tool for automating the process of assigning data inputs to different categories. A dataset…

Human-Computer Interaction · Computer Science 2023-05-25 Hannes Kath , Bengt Lüers , Thiago S. Gouvêa , Daniel Sonntag

We introduce Disentangled360, an innovative 3D-aware technology that integrates the advantages of direction disentangled volume rendering with single-image 360{\deg} unique view synthesis for applications in medical imaging and natural…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Karthikeya KV , Narendra Bandaru

Current in vivo microscopy allows us detailed spatiotemporal imaging (3D+t) of complete organisms and offers insights into their development on the cellular level. Even though the imaging speed and quality is steadily improving,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-31 Sourabh Bhide , Ralf Mikut , Maria Leptin , Johannes Stegmaier

Fluorescence microscopy is a widely used method among cell biologists for studying the localization and co-localization of fluorescent protein. For microbial cell biologists, these studies often include tedious and time-consuming manual…

Computer Vision and Pattern Recognition · Computer Science 2020-09-29 Jonathan Reiner , Guy Azran , Gal Hyams

Deep-learning-based pipelines have shown the potential to revolutionalize microscopy image diagnostics by providing visual augmentations to a trained pathology expert. However, to match human performance, the methods rely on the…

Accurately perceiving an object's pose and shape is essential for precise grasping and manipulation. Compared to common vision-based methods, tactile sensing offers advantages in precision and immunity to occlusion when tracking and…

Robotics · Computer Science 2026-02-17 Hung-Jui Huang , Mohammad Amin Mirzaee , Michael Kaess , Wenzhen Yuan

Ascertaining the collective viability of cells in different cell culture conditions has typically relied on averaging colorimetric indicators and is often reported out in simple binary readouts. Recent research has combined viability…

Quantitative Methods · Quantitative Biology 2024-04-03 Kylie J. Trettner , Jeremy Hsieh , Weikun Xiao , Jerry S. H. Lee , Andrea M. Armani

In many real-world scientific problems, generating ground truth (GT) for supervised learning is almost impossible. The causes include limitations imposed by scientific instrument, physical phenomenon itself, or the complexity of modeling.…

Image and Video Processing · Electrical Eng. & Systems 2020-08-31 Arif Ahmed Sekh , Ida S. Opstad , Rohit Agarwal , Asa Birna Birgisdottir , Truls Myrmel , Balpreet Singh Ahluwalia , Krishna Agarwal , Dilip K. Prasad

Methods: We have developed a software suite (DataSet Tracker) for real-time analysis designed to run on computers, smartphones, and smart glasses hardware and suitable for resource-constrained, on-the-fly computing in microscopes without…

Quantitative Methods · Quantitative Biology 2025-08-13 Alexandre Matov

Scientific optical 3D modeling requires the possibility to implement highly flexible and customizable mathematical models as well as high computing power. However, established ray tracing software for optical design and modeling purposes…

Computational Engineering, Finance, and Science · Computer Science 2023-08-15 Andrej Keksel , Samuel Schmidt , Dietrich Beck , Jörg Seewig

The quest for deeper understanding of biological systems has driven the acquisition of increasingly larger multidimensional image datasets. Inspecting and manipulating data of this complexity is very challenging in traditional visualization…

Graphics · Computer Science 2018-08-23 Stanislav Pidhorskyi , Michael Morehead , Quinn Jones , George Spirou , Gianfranco Doretto

Automated cell segmentation in microscopy images is essential for biomedical research, yet conventional methods are labor-intensive and prone to error. While deep learning-based approaches have proven effective, they often require large…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Rüveyda Yilmaz , Kaan Keven , Yuli Wu , Johannes Stegmaier

Modern medicine demands innovations in medical education, particularly in the learning of human anatomy, traditionally taught through textbooks, dissections, and lectures. Virtual Reality (VR) has emerged as a promising tool to address the…

Human-Computer Interaction · Computer Science 2024-11-11 Myint Zu Than , Kian Meng Yap

Generating realistic tissue images with annotations is a challenging task that is important in many computational histopathology applications. Synthetically generated images and annotations are valuable for training and evaluating…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Srijay Deshpande , Fayyaz Minhas , Nasir Rajpoot

Tiny Machine Learning (TinyML) algorithms have seen extensive use in recent years, enabling wearable devices to be not only connected but also genuinely intelligent by running machine learning (ML) computations directly on-device. Among…

Machine Learning · Computer Science 2025-11-21 Massimo Pavan , Claudio Galimberti , Manuel Roveri

Neurosurgery requires exceptional precision and comprehensive preoperative planning to ensure optimal patient outcomes. Despite technological advancements, there remains a need for intuitive, accessible tools to enhance surgical preparation…

Robotics · Computer Science 2024-11-06 Hon Lung Ho , Yupeng Wang , An Wang , Long Bai , Hongliang Ren

Microscopy image analysis is fundamental for different applications, from diagnosis to synthetic engineering and environmental monitoring. Modern acquisition systems have granted the possibility to acquire an escalating amount of images,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-26 Jacopo Dapueto , Vito Paolo Pastore , Nicoletta Noceti , Francesca Odone