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Neonates do not have the ability to either articulate pain or communicate it non-verbally by pointing. The current clinical standard for assessing neonatal pain is intermittent and highly subjective. This discontinuity and subjectivity can…
Accurate interpretation of knee MRI scans relies on expert clinical judgment, often with high variability and limited scalability. Existing radiomic approaches use a fixed set of radiomic features (the signature), selected at the population…
Clinical information extraction, which involves structuring clinical concepts from unstructured medical text, remains a challenging problem that could benefit from the inclusion of tabular background information available in electronic…
Clinical depression or Major Depressive Disorder (MDD) is a common and serious medical illness. In this paper, a deep recurrent neural network-based framework is presented to detect depression and to predict its severity level from speech.…
The technical capacity to monitor patients with a mobile device has drastically expanded, but data produced from this approach are often difficult to interpret. We present a solution to produce a meaningful representation of patient status…
Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…
The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…
Managing post-surgical pain is critical for successful surgical outcomes. One of the challenges of pain management is accurately assessing the pain level of patients. Self-reported numeric pain ratings are limited because they are…
Chronic neck pain is a leading cause of disability worldwide, and current treatment selection remains largely trial and error. We present a machine learning framework that uses electroencephalography to predict treatment efficacy in…
Facial pain expression is an important modality for assessing pain, especially when the patient's verbal ability to communicate is impaired. The facial muscle-based action units (AUs), which are defined by the Facial Action Coding System…
It is now recognized that important information can be extracted from the brain spontaneous activity, as exposed by recent analysis using a repertoire of computational methods. In this context a novel method, based on a blind deconvolution…
Identifying a patient's key problems over time is a common task for providers at the point care, yet a complex and time-consuming activity given current electric health records. To enable a problem-oriented summarizer to identify a…
Poor sitting posture is a critical yet often overlooked factor contributing to long-term musculoskeletal disorders and physiological dysfunctions. Existing sitting posture monitoring systems, although leveraging visual, IMU, or…
Deep phenotyping is the detailed description of patient signs and symptoms using concepts from an ontology. The deep phenotyping of the numerous physician notes in electronic health records requires high throughput methods. Over the past…
Chronic pain is a widespread and debilitating condition that affects millions of individuals worldwide. Recent research has unveiled a connection between chronic pain and epigenetic processes, shedding light on the complex interplay between…
In recent years, neuroimaging has undergone a paradigm shift, moving away from the traditional brain mapping approach toward developing integrated, multivariate brain models that can predict categories of mental events. However, large…
Large language models (LLMs) increasingly exhibit human-like linguistic behaviors and internal representations that they could serve as computational simulators of language cognition. We ask whether LLMs can be systematically manipulated to…
There are two fundamental problems in applying deep learning/machine learning methods to disease classification tasks, one is the insufficient number and poor quality of training samples; another one is how to effectively fuse multiple…
The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…
Cardiovascular diseases are becoming increasingly prevalent in modern society, with a profound impact on global health and well-being. These Cardiovascular disorders are complex and multifactorial, influenced by genetic predispositions,…