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The reconstruction of cerebral cortex surfaces from brain MRI scans is instrumental for the analysis of brain morphology and the detection of cortical thinning in neurodegenerative diseases like Alzheimer's disease (AD). Moreover, for a…

Neurons and Cognition · Quantitative Biology 2022-10-05 Anne-Marie Rickmann , Fabian Bongratz , Sebastian Pölsterl , Ignacio Sarasua , Christian Wachinger

The occurrence of a critical period of plasticity in the visual cortex has long been established, yet its function in normal development is not fully understood. Here we show that as the late phase of the critical period unfolds, different…

Neurons and Cognition · Quantitative Biology 2015-05-13 Matthias Kaschube , Michael Schnabel , Siegrid Löwel , Fred Wolf

Background: People with bipolar disorder (BD) tend to show widespread cognitive impairment compared to healthy controls. Impairments in processing speed (PS), attention, and executive function (EF) may represent 'core' impairments that have…

Neurons and Cognition · Quantitative Biology 2023-11-06 Bethany Little , Carly Flowers , Andrew Blamire , Peter Thelwall , John-Paul Taylor , Peter Gallagher , David Andrew Cousins , Yujiang Wang

The critical behaviour of correlation functions near a boundary is modified from that in the bulk. When the boundary is smooth this is known to be characterised by the surface scaling dimension $\xt$. We consider the case when the boundary…

Statistical Mechanics · Physics 2009-10-31 John Cardy

The primate visual system has an exquisite ability to discriminate partially occluded shapes. Recent electrophysiological recordings suggest that response dynamics in intermediate visual cortical area V4, shaped by feedback from prefrontal…

Neurons and Cognition · Quantitative Biology 2016-12-19 Hannah Choi , Anitha Pasupathy , Eric Shea-Brown

Microscopic analysis of histological sections is considered the "gold standard" to verify structural parcellations in the human brain. Its high resolution allows the study of laminar and columnar patterns of cell distributions, which build…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Hannah Spitzer , Katrin Amunts , Stefan Harmeling , Timo Dickscheid

The brain achieves stability and plasticity in a topologically complex, shifting world through Metric-Topology Factorization (MTF), separating discrete topological indexing for context selection from continuous metric condensation for local…

Neurons and Cognition · Quantitative Biology 2026-03-05 Xin Li

Like a rocket being propelled into space, evolution has engineered flies to launch into adulthood via multiple stages. Flies develop and deploy two distinct bodies, linked by the transformative process of metamorphosis. The fly larva is a…

Neurons and Cognition · Quantitative Biology 2022-01-12 Sweta Agrawal , John C Tuthill

Nervous systems are characterized by neurons displaying a diversity of morphological shapes. Traditionally, different shapes have been qualitatively described based on visual inspection and quantitatively described based on morphometric…

Neurons and Cognition · Quantitative Biology 2016-03-29 Lida Kanari , Paweł Dłotko , Martina Scolamiero , Ran Levi , Julian Shillcock , Kathryn Hess , Henry Markram

Brain development involves a sequence of structural changes from early stages of the embryo until several months after birth. Currently, ultrasound is the established technique for screening due to its ability to acquire dynamic images in…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Mariano Cabezas , Yago Diez , Clara Martinez-Diago , Anna Maroto

The idea that complex systems have a hierarchical modular organization originates in the early 1960s and has recently attracted fresh support from quantitative studies of large scale, real-life networks. Here we investigate the hierarchical…

Data Analysis, Statistics and Probability · Physics 2010-04-20 D. Meunier , R. Lambiotte , A. Fornito , K. D. Ersche , E. T. Bullmore

Accurate reconstruction of neuronal morphology is essential for classifying cell types and understanding brain connectivity. Recent advances in imaging and reconstruction techniques have greatly expanded the scale and quality of neuronal…

Neurons and Cognition · Quantitative Biology 2025-08-05 Wu Chen , Mingwei Liao , Xueyan Jia , Xiaowei Chen , Chi Xiao , Qingming Luo , Hui Gong , Anan Li

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Cortical neurons exhibit a hierarchy of timescales across brain regions in response to input stimuli, which is thought to be crucial for information processing of different temporal scales. Modeling studies suggest that both intra-regional…

Neurons and Cognition · Quantitative Biology 2024-12-24 Yang Qi , Jiexiang Wang , Weiyang Ding , Gustavo Deco , Viktor Jirsa , Wenlian Lu , Jianfeng Feng

The scaling property of the brain dynamics is studied based on the zero-crossing of the local electroencephalographic (EEG) recording taken from healthy young adults in eyes closed and eyes open. Evidence of coupling between the EEG fractal…

Biological Physics · Physics 2007-05-23 Der Chyan Lin , Asif Sharif , Hon Kwan

Information propagation characterizes how input correlations evolve across layers in deep neural networks. This framework has been well studied using mean-field theory, which assumes infinitely wide networks. However, these assumptions…

Machine Learning · Computer Science 2026-01-21 Giuseppe Alessio D'Inverno , Zhiyuan Hu , Leo Davy , Michael Unser , Gianluigi Rozza , Jonathan Dong

The human brain forms functional networks on all spatial scales. Modern fMRI scanners allow to resolve functional brain data in high resolutions, allowing to study large-scale networks that relate to cognitive processes. The analysis of…

Neurons and Cognition · Quantitative Biology 2019-05-14 Melanie Weber , Johannes Stelzer , Emil Saucan , Alexander Naitsat , Gabriele Lohmann , Jürgen Jost

The visual system is hierarchically organized to process visual information in successive stages. Neural representations vary drastically across the first stages of visual processing: at the output of the retina, ganglion cell receptive…

Neurons and Cognition · Quantitative Biology 2019-01-07 Jack Lindsey , Samuel A. Ocko , Surya Ganguli , Stephane Deny

Brain disorders in the early and late life of humans potentially share pathological alterations in brain functions. However, the key evidence from neuroimaging data for pathological commonness remains unrevealed. To explore this hypothesis,…

Artificial Intelligence · Computer Science 2023-02-24 Mianxin Liu , Jingyang Zhang , Yao Wang , Yan Zhou , Fang Xie , Qihao Guo , Feng Shi , Han Zhang , Qian Wang , Dinggang Shen

Brain aging is a widely studied longitudinal process throughout which the brain undergoes considerable morphological changes and various machine learning approaches have been proposed to analyze it. Within this context, brain age prediction…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Matthias Wilms , Jordan J. Bannister , Pauline Mouches , M. Ethan MacDonald , Deepthi Rajashekar , Sönke Langner , Nils D. Forkert