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Optical aberrations significantly degrade image quality in microscopy, particularly when imaging deeper into samples. These aberrations arise from distortions in the optical wavefront and can be mathematically represented using Zernike…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Yong En Kok , Bowen Deng , Alexander Bentley , Andrew J. Parkes , Michael G. Somekh , Amanda J. Wright , Michael P. Pound

We propose a deconvolution algorithm for images blurred and degraded by a Poisson noise. The algorithm uses a fast proximal backward-forward splitting iteration. This iteration minimizes an energy which combines a \textit{non-linear} data…

Applications · Statistics 2008-12-18 François-Xavier Dupé , Jalal Fadili , Jean Luc Starck

Fourier ptychography is a recently explored imaging method for overcoming the diffraction limit of conventional cameras with applications in microscopy and yielding high-resolution images. In order to splice together low-resolution images…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Yican Chen , Zhi Luo , Xia Wu , Huidong Yang , Bo Huang

Deconvolution is the most widely used aberration correction technique in microscopy, however most techniques assume that the aberrations are the same for each point in the image, which is rarely true. Methods for tracking spatially varying…

Optics · Physics 2025-12-02 Jakub Czuchnowski , Chuan Li , Hongli Ni , Brandon Weissbourd , Jerome Mertz

Point-spread function (PSF) estimation in spatially undersampled images is challenging because large pixels average fine-scale spatial information. This is problematic when fine-resolution details are necessary, as in optimal photometry…

Instrumentation and Methods for Astrophysics · Physics 2021-02-03 Teresa Symons , Michael Zemcov , James Bock , Yun-Ting Cheng , Brendan Crill , Christopher Hirata , Stephanie Venuto

High quality imaging usually requires bulky and expensive lenses to compensate geometric and chromatic aberrations. This poses high constraints on the optical hash or low cost applications. Although one can utilize algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-08-20 Xiu Li , Jinli Suo , Weihang Zhang , Xin Yuan , Qionghai Dai

Ptychography is a powerful imaging technique that is used in a variety of fields, including materials science, biology, and nanotechnology. However, the accuracy of the reconstructed ptychography image is highly dependent on the accuracy of…

Applied Physics · Physics 2024-06-03 Ming Du , Tao Zhou , Junjing Deng , Daniel J. Ching , Steven Henke , Mathew J. Cherukara

Due to image blurring image deconvolution is often used for studying biological structures in fluorescence microscopy. Fluorescence microscopy image volumes inherently suffer from intensity inhomogeneity, blur, and are corrupted by various…

Computer Vision and Pattern Recognition · Computer Science 2019-07-15 Soonam Lee , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

The recovery of morphologically accurate anatomical images from deformed ones is challenging in ultrasound (US) image acquisition, but crucial to accurate and consistent diagnosis, particularly in the emerging field of computer-assisted…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Zhongliang Jiang , Yue Zhou , Dongliang Cao , Nassir Navab

In the imaging process of an astronomical telescope, the deconvolution of its beam or Point Spread Function (PSF) is a crucial task. However, deconvolution presents a classical and challenging inverse computation problem. In scenarios where…

Instrumentation and Methods for Astrophysics · Physics 2024-03-05 Shulei Ni , Yisheng Qiu , Yunchun Chen , Zihao Song , Hao Chen , Xuejian Jiang , Huaxi Chen

Recent developments in fluorescence microscopy allow capturing high-resolution 3D images over time for living model organisms. To be able to image even large specimens, techniques like multi-view light-sheet imaging record different…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Canyu Yang , Dennis Eschweiler , Johannes Stegmaier

Super-resolution reconstruction techniques entail the utilization of software algorithms to transform one or more sets of low-resolution images captured from the same scene into high-resolution images. In recent years, considerable…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Hao Yan , Zixiang Wang , Zhengjia Xu , Zhuoyue Wang , Zhizhong Wu , Ranran Lyu

Sample-induced aberrations and optical imperfections limit the resolution of fluorescence microscopy. Phase diversity is a powerful technique that leverages complementary phase information in sequentially acquired images with deliberately…

Low-light image enhancement is a classical computer vision problem aiming to recover normal-exposure images from low-light images. However, convolutional neural networks commonly used in this field are good at sampling low-frequency local…

Computer Vision and Pattern Recognition · Computer Science 2022-09-19 Yunliang Zhuang , Zhuoran Zheng , Chen Lyu

Phase diversity is a widefield aberration correction method that uses multiple images to estimate the phase aberration at the pupil plane of an imaging system by solving an optimization problem. This estimated aberration can then be used to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-03 Nikolaj Reiser , Min Guo , Hari Shroff , Patrick J. La Riviere

Instrumental aberrations strongly limit high-contrast imaging of exoplanets, especially when they produce quasistatic speckles in the science images. With the help of recent advances in deep learning, we have developed in previous works an…

Instrumentation and Methods for Astrophysics · Physics 2022-11-14 Maxime Quesnel , Gilles Orban de Xivry , Olivier Absil , Gilles Louppe

This Point spread function (PSF) plays a crucial role in many computational imaging applications, such as shape from focus/defocus, depth estimation, and fluorescence microscopy. However, the mathematical model of the defocus process is…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Renzhi He , Yan Zhuang , Boya Fu , Fei Liu

Non-blind deconvolution aims to restore a sharp image from its blurred counterpart given an obtained kernel. Existing deep neural architectures are often built based on large datasets of sharp ground truth images and trained with…

Computer Vision and Pattern Recognition · Computer Science 2023-10-04 Tomáš Chobola , Gesine Müller , Veit Dausmann , Anton Theileis , Jan Taucher , Jan Huisken , Tingying Peng

We report a novel generalized optical measurement system and computational approach to determine and correct aberrations in optical systems. We developed a computational imaging method capable of reconstructing an optical system's…

Image and Video Processing · Electrical Eng. & Systems 2019-01-10 Jaebum Chung , Gloria W. Martinez , Karen Lencioni , Srinivas Sadda , Changhuei Yang

Monocular depth estimation and image deblurring are two fundamental tasks in computer vision, given their crucial role in understanding 3D scenes. Performing any of them by relying on a single image is an ill-posed problem. The recent…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Saqib Nazir , Lorenzo Vaquero , Manuel Mucientes , Víctor M. Brea , Daniela Coltuc