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Clinical natural language processing requires methods that can address domain-specific challenges, such as complex medical terminology and clinical contexts. Recently, large language models (LLMs) have shown promise in this domain. Yet,…

Computation and Language · Computer Science 2025-01-28 Ran Xu , Hejie Cui , Yue Yu , Xuan Kan , Wenqi Shi , Yuchen Zhuang , Wei Jin , Joyce Ho , Carl Yang

Pre-trained Language Models (PLMs) are trained on vast unlabeled data, rich in world knowledge. This fact has sparked the interest of the community in quantifying the amount of factual knowledge present in PLMs, as this explains their…

Computation and Language · Computer Science 2023-12-06 Paul Youssef , Osman Alperen Koraş , Meijie Li , Jörg Schlötterer , Christin Seifert

When addressing professional questions in the biomedical domain, humans typically acquire multiple pieces of information as evidence and engage in multifaceted analysis to provide high-quality answers. Current LLM-based question answering…

Computation and Language · Computer Science 2025-09-03 Chang Zong , Jian Wan , Siliang Tang , Lei Zhang

Language models (LMs) increasingly drive real-world applications that require world knowledge. However, the internal processes through which models turn data into representations of knowledge and beliefs about the world, are poorly…

Computation and Language · Computer Science 2025-09-04 Daniela Gottesman , Alon Gilae-Dotan , Ido Cohen , Yoav Gur-Arieh , Marius Mosbach , Ori Yoran , Mor Geva

Large Language Models (LLMs) have demonstrated remarkable success in diverse natural language processing (NLP) tasks in general domains. However, LLMs sometimes generate responses with the hallucination about medical facts due to limited…

Computation and Language · Computer Science 2025-01-14 Haochun Wang , Sendong Zhao , Zewen Qiang , Zijian Li , Nuwa Xi , Yanrui Du , MuZhen Cai , Haoqiang Guo , Yuhan Chen , Haoming Xu , Bing Qin , Ting Liu

Electronic Health Records (EHRs) offer considerable potential for clinical prediction, but their complexity and heterogeneity challenge traditional machine learning. Domain-specific EHR foundation models trained on unlabeled EHR data have…

Large Language Models (LLMs) often struggle with dynamically changing knowledge and handling unknown static information. Retrieval-Augmented Generation (RAG) is employed to tackle these challenges and has a significant impact on improving…

Computation and Language · Computer Science 2025-09-18 Zhen Zhang , Xinyu Wang , Yong Jiang , Zile Qiao , Zhuo Chen , Guangyu Li , Feiteng Mu , Mengting Hu , Pengjun Xie , Fei Huang

Knowledge enhanced pre-trained language models (K-PLMs) are shown to be effective for many public tasks in the literature but few of them have been successfully applied in practice. To address this problem, we propose K-AID, a systematic…

Artificial Intelligence · Computer Science 2021-09-23 Fu Sun , Feng-Lin Li , Ruize Wang , Qianglong Chen , Xingyi Cheng , Ji Zhang

Factual knowledge extraction aims to explicitly extract knowledge parameterized in pre-trained language models for application in downstream tasks. While prior work has been investigating the impact of supervised fine-tuning data on the…

Computation and Language · Computer Science 2025-05-30 Xuan Gong , Hanbo Huang , Shiyu Liang

Generative pre-trained transformer (GPT) models have shown promise in clinical entity and relation extraction tasks because of their precise extraction and contextual understanding capability. In this work, we further leverage the Unified…

Computation and Language · Computer Science 2024-07-16 Kriti Bhattarai , Inez Y. Oh , Zachary B. Abrams , Albert M. Lai

Vision-language models (VLMs) are increasingly adapted through domain-specific fine-tuning, yet it remains unclear whether this improves reasoning beyond superficial visual cues, particularly in high-stakes domains like medicine. We…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Oliver McLaughlin , Daniel Shubin , Carsten Eickhoff , Ritambhara Singh , William Rudman , Michal Golovanevsky

Language models often struggle with handling factual knowledge, exhibiting factual hallucination issue. This makes it vital to evaluate the models' ability to recall its parametric knowledge about facts. In this study, we introduce a…

Computation and Language · Computer Science 2024-10-10 Xin Zhao , Naoki Yoshinaga , Daisuke Oba

Knowledge infusion is a promising method for enhancing Large Language Models for domain-specific NLP tasks rather than pre-training models over large data from scratch. These augmented LLMs typically depend on additional pre-training or…

Computation and Language · Computer Science 2024-03-05 Kinshuk Vasisht , Balaji Ganesan , Vikas Kumar , Vasudha Bhatnagar

Previous studies have revealed that vanilla pre-trained language models (PLMs) lack the capacity to handle knowledge-intensive NLP tasks alone; thus, several works have attempted to integrate external knowledge into PLMs. However, despite…

Computation and Language · Computer Science 2023-10-12 Yunzhi Yao , Peng Wang , Shengyu Mao , Chuanqi Tan , Fei Huang , Huajun Chen , Ningyu Zhang

In this paper, we address reasoning tasks from open vocabulary Knowledge Bases (openKBs) using state-of-the-art Neural Language Models (NLMs) with applications in scientific literature. For this purpose, self-attention based NLMs are…

In recent years, there has been substantial progress in using pretrained Language Models (LMs) on a range of tasks aimed at improving the understanding of biomedical texts. Nonetheless, existing biomedical LLMs show limited comprehension of…

Computation and Language · Computer Science 2025-09-10 Andrey Sakhovskiy , Elena Tutubalina

Relation extraction is a fundamental problem in natural language processing. Most existing models are defined for relation extraction in the general domain. However, their performance on specific domains (e.g., biomedicine) is yet unclear.…

Computation and Language · Computer Science 2021-12-14 Yongkang Li

Pre-trained language models (PLM) have advanced the state-of-the-art across NLP applications, but lack domain-specific knowledge that does not naturally occur in pre-training data. Previous studies augmented PLMs with symbolic knowledge for…

Computation and Language · Computer Science 2022-12-19 Denis Emelin , Daniele Bonadiman , Sawsan Alqahtani , Yi Zhang , Saab Mansour

Entities lie in the heart of biomedical natural language understanding, and the biomedical entity linking (EL) task remains challenging due to the fine-grained and diversiform concept names. Generative methods achieve remarkable…

Computation and Language · Computer Science 2022-05-24 Hongyi Yuan , Zheng Yuan , Sheng Yu

While pre-trained language models (PLMs) have shown evidence of acquiring vast amounts of knowledge, it remains unclear how much of this parametric knowledge is actually usable in performing downstream tasks. We propose a systematic…

Computation and Language · Computer Science 2023-05-25 Amirhossein Kazemnejad , Mehdi Rezagholizadeh , Prasanna Parthasarathi , Sarath Chandar
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