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Magnetic Resonance Imaging (MRI) of the fetal brain has become a key tool for studying brain development in vivo. Yet, its assessment remains challenging due to variability in brain maturation, imaging protocols, and uncertain estimates of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Johannes Tischer , Patric Kienast , Marlene Stümpflen , Gregor Kasprian , Georg Langs , Roxane Licandro

We introduce a conditional implicit neural atlas (CINA) for spatio-temporal atlas generation from Magnetic Resonance Images (MRI) of the neurotypical and pathological fetal brain, that is fully independent of affine or non-rigid…

Early brain development is crucial for lifelong neurodevelopmental health. However, current clinical practice offers limited knowledge of normal embryonic brain anatomy on ultrasound, despite the brain undergoing rapid changes within the…

Spatio-temporal fetal brain atlases are important for characterizing normative neurodevelopment and identifying congenital anomalies. However, existing atlas construction pipelines necessitate days for slice-to-volume reconstruction (SVR)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Xiaotian Hu , Mingxuan Liu , Hongjia Yang , Juncheng Zhu , Yijin Li , Yifei Chen , Haoxiang Li , Tongxi Song , Zihan Li , Yingqi Hao , Ziyu Li , Yujin Zhang , Gang Ning , Yi Liao , Haibo Qu , Qiyuan Tian

We present a method for fast biomedical image atlas construction using neural fields. Atlases are key to biomedical image analysis tasks, yet conventional and deep network estimation methods remain time-intensive. In this preliminary work,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Zeen Chi , Zhongxiao Cong , Clinton J. Wang , Yingcheng Liu , Esra Abaci Turk , P. Ellen Grant , S. Mazdak Abulnaga , Polina Golland , Neel Dey

Building of atlases plays a crucial role in the analysis of brain images. In scenarios where early growth, aging or disease trajectories are of key importance, longitudinal atlases become necessary as references, most often created from…

Image and Video Processing · Electrical Eng. & Systems 2020-03-12 Heejong Kim , Martin Styner , Joseph Piven , Guido Gerig

Characterizing in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building on prior spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, a spatiotemporal (4D) atlas…

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

The human brain undergoes rapid development during the third trimester of pregnancy. In this work, we model the neonatal development of the infant brain in this age range. As a basis, we use MR images of preterm- and term-birth neonates…

Image and Video Processing · Electrical Eng. & Systems 2024-08-19 Florentin Bieder , Paul Friedrich , Hélène Corbaz , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

Magnetic resonance imaging of fetal and neonatal brains reveals rapid neurodevelopment marked by substantial anatomical changes unfolding within days. Studying this critical stage of the developing human brain, therefore, requires accurate…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Maik Dannecker , Vasiliki Sideri-Lampretsa , Sophie Starck , Angeline Mihailov , Mathieu Milh , Nadine Girard , Guillaume Auzias , Daniel Rueckert

We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework. Our approach consists of two sequential networks with a specifically…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Wietske A. P. Bastiaansen , Melek Rousian , Régine P. M. Steegers-Theunissen , Wiro J. Niessen , Anton Koning , Stefan Klein

Automated fetal brain extraction from full-uterus MRI is a challenging task due to variable head sizes, orientations, complex anatomy, and prevalent artifacts. While deep-learning (DL) models trained on synthetic images have been successful…

Image and Video Processing · Electrical Eng. & Systems 2024-10-30 Javid Dadashkarimi , Valeria Pena Trujillo , Camilo Jaimes , Lilla Zöllei , Malte Hoffmann

Brain development involves a sequence of structural changes from early stages of the embryo until several months after birth. Currently, ultrasound is the established technique for screening due to its ability to acquire dynamic images in…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Mariano Cabezas , Yago Diez , Clara Martinez-Diago , Anna Maroto

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Fetal brain imaging is a cornerstone of prenatal screening and early diagnosis of congenital anomalies. Knowledge of fetal gestational age is the key to the accurate assessment of brain development. This study develops an attention-based…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Liyue Shen , Katie Shpanskaya , Edward Lee , Emily McKenna , Maryam Maleki , Quin Lu , Safwan Halabi , John Pauly , Kristen Yeom

Fetal brain extraction is a necessary first step in most computational fetal brain MRI pipelines. However, it has been a very challenging task due to non-standard fetal head pose, fetal movements during examination, and vastly heterogeneous…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdoğmuş , Ali Gholipour

Understanding human fetal neurodevelopment is of great clinical importance as abnormal development is linked to adverse neuropsychiatric outcomes after birth. Recent advances in functional Magnetic Resonance Imaging (fMRI) have provided new…

Image and Video Processing · Electrical Eng. & Systems 2019-06-11 Xiangrui Li , Jasmine Hect , Moriah Thomason , Dongxiao Zhu

Longitudinal image registration enables studying temporal changes in brain morphology which is useful in applications where monitoring the growth or atrophy of specific structures is important. However this task is challenging due to;…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Aisha L. Shuaibu , Kieran A. Gibb , Peter A. Wijeratne , Ivor J. A. Simpson

Fetal brain segmentation is an important first step for slice-level motion correction and slice-to-volume reconstruction in fetal MRI. Fast and accurate segmentation of the fetal brain on fetal MRI is required to achieve real-time fetal…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdogmus , Ali Gholipour

This paper presents FeTal-SAM, a novel adaptation of the Segment Anything Model (SAM) tailored for fetal brain MRI segmentation. Traditional deep learning methods often require large annotated datasets for a fixed set of labels, making them…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Qi Zeng , Weide Liu , Bo Li , Ryne Didier , P. Ellen Grant , Davood Karimi
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