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Prenatal ultrasound evaluates fetal growth and detects congenital abnormalities during pregnancy, but the examination of ultrasound images by radiologists requires expertise and sophisticated equipment, which would otherwise fail to improve…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Yang Qi , Jiaxin Cai , Jing Lu , Runqing Xiong , Rongshang Chen , Liping Zheng , Duo Ma

Brain atlases are essential for reducing the dimensionality of neuroimaging data and enabling interpretable analysis. However, most existing atlases are predefined, group-level templates with limited flexibility and resolution. We present…

Neurons and Cognition · Quantitative Biology 2025-09-23 Mo Wang , Kaining Peng , Jingsheng Tang , Hongkai Wen , Quanying Liu

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Marianne Rakic , Andrew Hoopes , S. Mazdak Abulnaga , Mert R. Sabuncu , John V. Guttag , Adrian V. Dalca

Establishing dense volumetric correspondences across anatomical shapes is essential for group-level analysis but remains challenging for implicit neural representations. Most existing implicit registration methods rely on supervision near…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Athena Taymourtash , S. Mazdak Abulnaga , Esra Abaci Turk , P. Ellen Grant , Polina Golland

Ultrasound is a widely accessible and cost-effective medical imaging tool commonly used for prenatal evaluation of the fetal brain. However, it has limitations, particularly in the third trimester, where the complexity of the fetal brain…

Image and Video Processing · Electrical Eng. & Systems 2025-04-04 Naomi Silverstein , Efrat Leibowitz , Ron Beloosesky , Haim Azhari

Developing innovative informatics approaches aimed to enhance fetal monitoring is a burgeoning field of study in reproductive medicine. Several reviews have been conducted regarding Artificial intelligence (AI) techniques to improve…

T2 mapping in fetal brain MRI has the potential to improve characterization of the developing brain, especially at mid-field (0.55T), where T2 decay is slower. However, this is challenging as fetal MRI acquisition relies on multiple…

Missing scans are inevitable in longitudinal studies due to either subject dropouts or failed scans. In this paper, we propose a deep learning framework to predict missing scans from acquired scans, catering to longitudinal infant studies.…

Image and Video Processing · Electrical Eng. & Systems 2022-08-10 Yunzhi Huang , Sahar Ahmad , Luyi Han , Shuai Wang , Zhengwang Wu , Weili Lin , Gang Li , Li Wang , Pew-Thian Yap

A computational anatomy atlas is a set of internal organ geometries. It is based on data of real patients and complemented with virtual cases by using a some numerical approach. Atlases are in demand in computational physiology, especially…

Tissues and Organs · Quantitative Biology 2023-03-21 Konstantin Ushenin , Maksim Dzhigil , Vladislav Dordiuk

This study introduces a deep learning framework for the inferential exploration of latent representations in 3D brain MRI, leveraging a simple convolutional autoencoder with a hierarchical encoder and a compact latent space. Trained on…

Applications · Statistics 2026-05-25 J. M. Gorriz , F. Segovia , C. Jimenez , J. E. Arco , F. J. Martinez , J Ramirez , S. Abulikemu , J. Suckling

Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Haoran Dou , Davood Karimi , Caitlin K. Rollins , Cynthia M. Ortinau , Lana Vasung , Clemente Velasco-Annis , Abdelhakim Ouaalam , Xin Yang , Dong Ni , Ali Gholipour

Fetal brain MRI is useful for diagnosing brain abnormalities but is challenged by fetal motion. The current protocol for T2-weighted fetal brain MRI is not robust to motion so image volumes are degraded by inter- and intra- slice motion…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Junshen Xu , Sayeri Lala , Borjan Gagoski , Esra Abaci Turk , P. Ellen Grant , Polina Golland , Elfar Adalsteinsson

Early infancy is a rapid and dynamic neurodevelopmental period for behavior and neurocognition. Longitudinal magnetic resonance imaging (MRI) is an effective tool to investigate such a crucial stage by capturing the developmental…

Image and Video Processing · Electrical Eng. & Systems 2024-02-22 Lianghu Guo , Tianli Tao , Xinyi Cai , Zihao Zhu , Jiawei Huang , Lixuan Zhu , Zhuoyang Gu , Haifeng Tang , Rui Zhou , Siyan Han , Yan Liang , Qing Yang , Dinggang Shen , Han Zhang

One of the biggest challenges for deep learning algorithms in medical image analysis is the indiscriminate mixing of image properties, e.g. artifacts and anatomy. These entangled image properties lead to a semantically redundant feature…

Machine Learning · Computer Science 2019-08-22 Qingjie Meng , Nick Pawlowski , Daniel Rueckert , Bernhard Kainz

Diffusion-weighted Magnetic Resonance Imaging (dMRI) is increasingly used to study the fetal brain in utero. An important computation enabled by dMRI is streamline tractography, which has unique applications such as tract-specific analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-03-06 Camilo Calixto , Camilo Jaimes , Matheus D. Soldatelli , Simon K. Warfield , Ali Gholipour , Davood Karimi

Deep learning has a great potential for estimating biomarkers in diffusion weighted magnetic resonance imaging (dMRI). Atlases, on the other hand, are a unique tool for modeling the spatio-temporal variability of biomarkers. In this paper,…

Medical Physics · Physics 2022-05-09 Davood Karimi , Ali Gholipour

MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in fetal MRI is segmentation of the fetal brain into different tissue classes.…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 N. Khalili , N. Lessmann , E. Turk , N. Claessens , R. de Heus , T. Kolk , M. A. Viergever , M. J. N. L. Benders , I. Isgum

Deep learning algorithms for predicting neuroimaging data have shown considerable promise in various applications. Prior work has demonstrated that deep learning models that take advantage of the data's 3D structure can outperform standard…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Yuda Bi , Anees Abrol , Zening Fu , Jiayu Chen , Jingyu Liu , Vince Calhoun