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We consider a susceptible, infected, and recovered infectious disease model which incorporates a vaccination rate. In particular, we study the problem of choosing the vaccination rate in order to reduce the number of infected individuals to…

Analysis of PDEs · Mathematics 2021-08-30 Ryan Hynd , Dennis Ikpe , Terrance Pendleton

Massive vaccination against pandemics such as Coronavirus SARS-CoV-2 presents several complexities. The criteria to assess public health policies are fundamental to distribute vaccines in an effective way in order to avoid as many…

Optimization and Control · Mathematics 2023-12-01 José Luis Sainz-Pardo , José Valero

Vaccination campaigns have both direct and indirect effects that act to control an infectious disease as it spreads through a population. Indirect effects arise when vaccinated individuals block disease transmission in any infection chains…

Populations and Evolution · Quantitative Biology 2024-05-08 Lixin Lin , Homayoun Hamedmoghadam , Robert Shorten , Lewi Stone

This paper studies an optimal control problem for a class of SIR epidemic models, in scenarios in which the infected population is constrained to be lower than a critical threshold imposed by the ICU (intensive care unit) capacity. The…

Optimization and Control · Mathematics 2024-12-31 Matteo Della Rossa , Lorenzo Freddi , Dan Goreac

One long-standing question in epidemiological research is how best to allocate limited amounts of vaccine or similar preventative measures in order to minimize the severity of an epidemic. Much of the literature on the problem of vaccine…

Social and Information Networks · Computer Science 2014-12-02 Krzysztof Drewniak , Joseph Helsing , Armin R. Mikler

As observed during the COVID-19 pandemic, high-income countries, such as the U.S., may exhibit vaccine nationalism during a pandemic: stockpiling doses of vaccine for their own citizens and being reluctant to distribute doses of the vaccine…

Populations and Evolution · Quantitative Biology 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

We develop a mechanistic model that classifies individuals both in terms of epidemiological status (SIR) and vaccination attitude (willing or unwilling), with the goal of discovering how disease spread is influenced by changing opinions…

Dynamical Systems · Mathematics 2024-08-16 Yi Jiang , Kristin M. Kurianski , Jane HyoJin Lee , Yanping Ma , Daniel Cicala , Glenn Ledder

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

The results of Kermack-McKendrick SIR model are planned to be reproduced by cellular automata (CA) lattice model. The CA algorithms are proposed to study the model of epidemic, systematically. The basic goal is to capture the effects of…

Populations and Evolution · Quantitative Biology 2022-08-30 Agniva Datta , Muktish Acharyya

In this paper we consider SIR epidemics on random graphs with clustering. To incorporate group structure of the underlying social network, we use a generalized version of the configuration model in which each node is a member of a specified…

Probability · Mathematics 2018-02-15 Carolina Fransson , Pieter Trapman

The SEIRS model, an extension of the SEIR model for analyzing and predicting the spread of virus infection, was further extended to consider the movement of people across regions. In contrast to previous models that con-sider the risk of…

Medical Physics · Physics 2021-07-01 Yukio Ohsawa , Teruaki Hayashi , Sae Kondo

In this work, effects of constant and time-dependent vaccination rates on the Susceptible-Exposed-Infected-Recovered-Susceptible (SEIRS) seasonal model are studied. Computing the Lyapunov exponent, we show that typical complex structures,…

We consider the spread of a supercritical stochastic SIR (Susceptible, Infectious, Recovered) epidemic on a configuration model random graph. We mainly focus on the final stages of a large outbreak and provide limit results for the duration…

Probability · Mathematics 2020-02-26 Abid Ali Lashari , Ana Serafimović , Pieter Trapman

In this paper we investigate the asymptotic behavior of some SIR models incorporating demography, bounded random transmission coefficient and a time-dependent vaccination strategy targeting the susceptible population. In this setting, we…

Populations and Evolution · Quantitative Biology 2025-10-27 Javier López-de-la-Cruz , Susana Merchán , Felipe Rivero , Javier Rodrigo

We propose a framework for the description of the effects of vaccinations on the spreading of an epidemic disease. Different vaccines can be dosed, each providing different immunization times and immunization levels. Differences due to…

Analysis of PDEs · Mathematics 2024-07-23 Rinaldo M. Colombo , Mauro Garavello

Stochastic models are widely used to investigate the spread of epidemics in a complex environment. This paper extends a deterministic SAIRS epidemic model to a stochastic case with limited patient capacity and exposure. We first study the…

Probability · Mathematics 2024-05-20 Xiaohui Zhang , Zhiming Li , Shenglong Chen , Jikai Yang

In this paper, we present stochastic synchronous cellular automaton defined on a square lattice. The automaton rules are based on the SEIR (susceptible $\to$ exposed $\to$ infected $\to$ recovered) model with probabilistic parameters…

Cellular Automata and Lattice Gases · Physics 2022-06-22 Szymon Biernacki , Krzysztof Malarz

In this work we consider a model of epidemic spreading coupled with an opinion dynamics in a fully-connected population. Regarding the opinion dynamics, the individuals may be in two distinct states, namely in favor or against a vaccination…

Physics and Society · Physics 2016-10-28 Marcelo A. Pires , Nuno Crokidakis

Non-pharmacological interventions (NPIs), and in particular social distancing, in conjunction with the advent of effective vaccines at the end of 2020, aspired for the development of a protective immunity shield against the spread of…

Vaccinations are an important tool in the prevention of disease. Vaccinations are generally voluntary for each member of a population and vaccination decisions are influenced by individual risk perceptions and contact structures within…

Physics and Society · Physics 2025-04-07 Kausutua Tjikundi , Mark Broom