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We consider a SIR model with vaccination strategy on a sparse configuration model random graph. We show the convergence of the system when the number of nodes grows and characterize the scaling limits. Then, we prove the existence of…

Probability · Mathematics 2021-02-26 Emanuel Javier Ferreyra , Matthieu Jonckheere , Juan Pablo Pinasco

We study vaccine budget-sharing strategies in the SIR (Susceptible-Infected-Recovered) model given a structured community network to investigate the benefit of sharing vaccine across communities. The network studied comprises two…

Physics and Society · Physics 2023-11-14 Felippe Alves , David Saad

The SEIR model is a compartmental model used to simulate the dynamics of an epidemic. In this chapter, we introduce two control functions in the compartmental SEIR model representing vaccination and plasma transfusion. Optimal control…

Optimization and Control · Mathematics 2021-07-23 Juliana Couras , Ivan Area , Juan J. Nieto , Cristiana J. Silva , Delfim F. M. Torres

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

Populations and Evolution · Quantitative Biology 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

Controlling and understanding epidemic outbreaks has recently drawn great interest in a large spectrum of research communities. Vaccination is one of the most well-established and effective strategies in order to contain an epidemic. In the…

Social and Information Networks · Computer Science 2023-05-29 Sourin Chatterjee , Ahad N. Zehmakan

In this work we propose and investigate a new strategy of vaccination, which we call "dynamic vaccination". In our model, susceptible people become aware that one or more of their contacts are infected, and thereby get vaccinated with…

Physics and Society · Physics 2019-01-09 L. G. Alvarez-Zuzek , M. A. Di Muro , S. Havlin , L. A. Braunstein

In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple…

Optimization and Control · Mathematics 2021-12-17 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

We consider an SLIARS mathematical epidemiology model including intervention in the form of vaccination and treatment. Contrary to classical models, it is assumed that treatment doses can be limited in availability. Mathematically, we show…

In this paper, we extend the classical SIRS (Susceptible-Infectious-Recovered-Susceptible) model from mathematical epidemiology by incorporating a vaccinated compartment, V, accounting for an imperfect vaccine with waning efficacy over…

Populations and Evolution · Quantitative Biology 2025-01-30 Joseph Páez Chávez , Aytül Gökçe , Thomas Götz , Burcu Gürbüz

We consider the $SEIRS$ epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. Within a compartmental realization of this…

Populations and Evolution · Quantitative Biology 2021-12-07 Jaroslav Ilnytskyi , Taras Patsahan

We investigate stochastic extinction in an epidemic model and the impact of random vaccinations in large populations formulated in terms of an optimal escape path. We find that different random vaccination strategies can have widely…

Biological Physics · Physics 2007-11-12 Alexandra S. Landsman , Ira B. Schwartz

This paper presents a vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population amounts as a refrain for…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , A. Ibeas , S. Alonso-Quesada

This paper is concerned with the analysis of vaccination strategies in a stochastic SIR (susceptible $\to$ infected $\to$ removed) model for the spread of an epidemic amongst a population of individuals with a random network of social…

Physics and Society · Physics 2016-11-16 Frank Ball , David Sirl

A linearization-based feedback-control strategy for a SEIR epidemic model is discussed. The vaccination objective is the asymptotically tracking of the removed-by-immunity population to the total population while achieving simultaneously…

Dynamical Systems · Mathematics 2011-03-24 M. De la Sen , A. Ibeas , S. Alonso-Quesada

SIR models, also with age structure, can be used to describe the evolution of an infective disease. A vaccination campaign influences this dynamics immunizing part of the susceptible individuals, essentially turning them into recovered…

Analysis of PDEs · Mathematics 2019-10-17 Rinaldo M. Colombo , Mauro Garavello

Now that SARS-CoV-2 (COVID-19) vaccines are developed, it is very important to plan its distribution strategy. In this paper, we formulated a multi-objective linear programming model to optimize vaccine distribution and applied it to the…

Populations and Evolution · Quantitative Biology 2021-01-28 Jose Marie Antonio Minoza , Vena Pearl Bongolan , Joshua Frankie Rayo

Most vaccines require multiple doses, the first to induce recognition and antibody production and subsequent doses to boost the primary response and achieve optimal protection. We show that properly prioritizing the administration of first…

We analyze infection spreading processes in a system where only a fraction $p$ of individuals can be affected by disease, while remaining $1-p$ individuals are immune. Such a picture can emerge as a natural consequence of previously…

Disordered Systems and Neural Networks · Physics 2021-12-06 V. Blavatska , Yu. Holovatch

This paper presents several simple linear vaccination-based control strategies for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total population…

Dynamical Systems · Mathematics 2011-03-28 M. De la Sen , S. Alonso-Quesada

We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and…

Populations and Evolution · Quantitative Biology 2022-06-28 Omar El Deeb , Maya Jalloul