Related papers: Sharp dose profiles for high precision proton ther…
High-quality proton beams generated by laser-plasma interactions are of significant interest for applications ranging from tumor therapy to fast ignition in inertial confinement fusion. However, simultaneously achieving high energy coupling…
A new strategy for radiation therapy dosimetry planning (RTDP) used to reduce dose estimation errors due to respiratory motion in breast treatment was illustrated and evaluated in this study. On CT data set acquired for breast treatment,…
Objective: To perform a comprehensive comparative analysis of proton, helium-ion, and carbon-ion computed tomography (CT) as direct imaging modalities for hadron therapy treatment planning, focusing on Relative Stopping Power (RSP)…
An improved acceleration scheme to produce protons with controlled divergence and concentrated energy density is studied using ultrashort ultraintense (USUI) laser pulse interaction with a tailored hole-target in target normal sheath…
The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…
Hadrontherapy is a novel technique of cancer radiation therapy which employs beams of charged hadrons, protons and carbon ions in particular. Due to their physical and radiobiological properties, they allow one to obtain a more conformal…
Radiotherapy planning is a critical aspect of cancer treatment, where the optimal selection of beam directions and dose distributions significantly impacts treatment efficacy and patient outcomes. Traditionally, this process involves…
Purpose: Beam range control is the essence of radiotherapy with heavy charged particles. In conventional broad-beam delivery, fine range adjustment is achieved by insertion of range shifting and compensating materials. In dosimetry, solid…
Objective: Real-time adaptive proton range verification systems based on produced neutrons require accurate information on their non-isotropic momentum distributions within short times, for which Monte Carlo (MC) methods are too…
Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…
Radiation therapy aims to deliver the prescribed amount of dose to a tumour at the same time as sparing the surrounding tissues as much as possible. In charged particle therapy, delivering the prescribed dose is equivalent to delivering the…
Proton Computed Tomography (pCT) provides a promising solution to enhance the accuracy of Relative Stopping Power (RSP) required for proton therapy planning. This research introduces a novel high-granularity pCT architecture that…
We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…
Imaging of nuclear gamma-ray lines in the 1-10 MeV range is far from being established in both medical and physical applications. In proton therapy, 4.4 MeV gamma rays are emitted from the excited nucleus of either 12^C^* or 11^B^* and are…
Today, intensity-modulated radiation therapy (IMRT) is one of the methods used to treat brain tumors. In conventional treatment planning methods, after identifying planning target volume (PTV), and organs at risk (OARs), and determining the…
Particle therapy is a well established clinical treatment of tumors. More than one hundred particle therapy centers are in operation world wide. The advantage of using hadrons like protons or carbon ions as particles for tumor irradiation…
Background: Dose calculation and optimization algorithms in proton therapy treatment planning often have high computational requirements regarding time and memory. This can hinder the implementation of efficient workflows in clinics and…
Range uncertainties in proton therapy hamper treatment precision. Prompt gamma-rays were suggested 16 years ago for real-time range verification, and have already shown promising results in clinical studies with collimated cameras.…
The radiotherapy of malignant diseases has reached much progress during the past decade. Thus, intensity modulated radiation therapy (IMRT) and VMAT (Rapidarc) now belong to the standard modalities of tumor treatment with high energy…
Cancer therapy for deep-seated tumors requires precise irradiation of a small target deep within the patient while minimizing radiation exposure to surrounding tissues. This can be accomplished with a round beam sharply converging towards a…