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In this paper we systematically apply the mathematical structures by time-evolving measures developed in a previous work to the macroscopic modeling of pedestrian flows. We propose a discrete-time Eulerian model, in which the space…

Mathematical Physics · Physics 2009-07-02 Benedetto Piccoli , Andrea Tosin

A simple model for the nonlinear collective transport of interacting particles in a random medium with strong disorder is introduced and analyzed. A finite threshold for the driving force divides the behavior into two regimes characterized…

Condensed Matter · Physics 2009-10-28 Joe Watson , Daniel S. Fisher

We study a continuum model of dislocation transport in order to investigate the formation of heterogeneous dislocation patterns. We propose a physical mechanism which relates the formation of heterogeneous patterns to the dynamics of a…

Materials Science · Physics 2018-08-29 Ronghai Wu , Daniel Tüzes , Péter Dusán Ispánovity , István Groma , Michael Zaiser

In both biological and artificial systems, concentration gradients can serve as a convenient mechanism for manipulating particles and generating motility. Particles that interact with a solute will move along its gradient; if they…

Soft Condensed Matter · Physics 2011-07-21 Gareth P. Alexander , Andrea J. Liu

Understanding the organization of collective motion in biological systems is an ongoing challenge. In this Paper we consider a minimal model of self-propelled particles with variable speed. Inspired by experimental data from schooling fish,…

Biological Physics · Physics 2015-06-04 Shradha Mishra , Kolbjørn Tunstrøm , Iain D. Couzin , Cristián Huepe

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

Statistical Mechanics · Physics 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

The progression of a cell population where each individual is characterized by the value of an internal variable varying with time (e.g. size, weight, and protein concentration) is typically modeled by a Population Balance Equation, a first…

Cell Behavior · Quantitative Biology 2016-04-20 Qasim Ali , Ali Elkamel , Frédéric Gruy , Claude Lambert , Eric Touboul

Collective motion in animal groups emerges from the interplay between individual variability and social coordination, yet connecting these scales quantitatively has remained a major challenge.Using high-resolution trajectories of schooling…

Other Condensed Matter · Physics 2026-01-15 Elena G. de Lamo , M. Carmen Miguel , Romualdo Pastor-Satorras

Collective cell migration is a multicellular phenomenon that arises in various biological contexts, including cancer and embryo development. "Collectiveness" can be promoted by cell-cell interactions such as co-attraction and contact…

Cell Behavior · Quantitative Biology 2023-10-03 Viktoria Freingruber , Kevin J. Painter , Mariya Ptashnyk , Linus Schumacher

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

Biological Physics · Physics 2017-03-30 Isabella R. Graf , Erwin Frey

We consider a integro-differential nonlinear model that describes the evolution of a population structured by a quantitative trait. The interactions between traits occur from competition for resources whose concentrations depend on the…

Analysis of PDEs · Mathematics 2011-12-05 Nicolas Champagnat , Pierre-Emmanuel Jabin

Dense suspensions of swimming bacteria are known to exhibit collective behaviour arising from the interplay of steric and hydrodynamic interactions. Unconfined suspensions exhibit transient, recurring vortices and jets, whereas those…

Biological Physics · Physics 2016-07-04 Hugo Wioland , Enkeleida Lushi , Raymond E. Goldstein

The process of polarization determines the head and tail of single cells. A mechanism of this kind frequently precedes the subsequent cell locomotion and it determines the direction of motion. The process of polarization has frequently been…

Biological Physics · Physics 2021-12-30 Eduardo Moreno , Sergio Alonso

Discontinuous dynamical systems with grazing solutions are discussed. The group property, continuation of solutions, continuity and smoothness of motions are thoroughly analyzed. A variational system around a grazing solution which depends…

Dynamical Systems · Mathematics 2016-04-20 Marat Akhmet , Aysegul Kivilcim

Growth (and resorption) of biological tissue is formulated in the continuum setting. The treatment is macroscopic, rather than cellular or sub-cellular. Certain assumptions that are central to classical continuum mechanics are revisited,…

Quantitative Methods · Quantitative Biology 2015-06-26 K. Garikipati , E. M. Arruda , K. Grosh , H. Narayanan , S. Calve

A connection is established between discrete stochastic model describing microscopic motion of fluctuating cells, and macroscopic equations describing dynamics of cellular density. Cells move towards chemical gradient (process called…

Biological Physics · Physics 2010-05-18 Pavel M. Lushnikov , Nan Chen , Mark Alber

The dynamics of active matter driven by interacting molecular motors has a non-potential structure at the local scale. However, we show that there exists a quasi-potential effectively describing the collective self-organization of the…

Biological Physics · Physics 2022-06-15 Haythem Chelly , Pierre Recho

The emerging collective motions of swarms of interacting agents are a subject of great interest in application areas ranging from biology to physics and robotics. In this paper, we conduct a careful analysis of the collective dynamics of a…

Adaptation and Self-Organizing Systems · Physics 2014-09-04 Klementyna Szwaykowska , Luis Mier-y-Teran Romero , Ira B. Schwartz

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

Cell-cell adhesion plays a vital role in the development and maintenance of multicellular organisms. One of its functions is regulation of cell migration, such as occurs, e.g. during embryogenesis or in cancer. In this work, we develop a…

Tissues and Organs · Quantitative Biology 2024-03-08 Anna Zhigun , Mabel Lizzy Rajendran