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Different families of models first developed for fluid mechanics have been extended to road, pedestrian, or intracellular transport. These models allow to describe the systems at different scales and to account for different aspects of…

Physics and Society · Physics 2017-09-20 Cecile Appert-Rolland

Aggregation and fragmentation of single molecules in the cell environment lead to a spectrum of diffusivities and to statistical laws of movement very different from typical Brownian motion. Current models of intracellular transport do not…

Statistical Mechanics · Physics 2020-07-08 M. Hidalgo-Soria , E. Barkai

Describing particle transport at the macroscopic or mesoscopic level in non-ideal environments poses fundamental theoretical challenges in domains ranging from inter and intra-cellular transport in biology to diffusion in porous media. Yet,…

Statistical Mechanics · Physics 2013-09-11 Marta Galanti , Duccio Fanelli , Francesco Piazza

We introduce and theoretically investigate a minimal particle-based model for a new class of active matter where particles exhibit directional, volume-conserving division in confinement while interacting sterically, mimicking cells in early…

Soft Condensed Matter · Physics 2024-10-01 Samantha R. Lish , Lukas Hupe , Ramin Golestanian , Philip Bittihn

In a system of noisy self-propelled particles with interactions that favor directional alignment, collective motion will appear if the density of particles increases beyond a certain threshold. In this paper, we argue that such a threshold…

Soft Condensed Matter · Physics 2010-03-29 Chiu Fan Lee

We propose a new approach for crowd motion models where the density constraint can only slow down the motion of each agent, with no effect on those agents who are not in a saturated area or who have no saturated density ''in front'' of…

Analysis of PDEs · Mathematics 2026-05-05 Nicolas Masson , Benoît Perthame , Filippo Santambrogio

Monod's law is a widely accepted phenomenology for bacterial growth. Since it has the same functional form as the Michaelis--Menten equation for enzyme kinetics, cell growth is often considered to be locally constrained by a single…

Cell Behavior · Quantitative Biology 2025-10-14 Jumpei F. Yamagishi , Tetsuhiro S. Hatakeyama

This paper studies a discrete dynamical system belonging to the class of the networks introduced by A.P.~Buslaev. The systems contains a finite set of contours. In any contour, there are cells and a group of particles. This group is called…

Optimization and Control · Mathematics 2021-12-28 P. A. Myshkis , A. G. Tatashev , M. V. Yashina

The classical problem of optimal transportation can be formulated as a linear optimization problem on a convex domain: among all joint measures with fixed marginals find the optimal one, where optimality is measured against a cost function.…

Optimization and Control · Mathematics 2012-11-29 Jonathan Korman , Robert J. McCann

Substrate-based cell motility is essential for fundamental biological processes, such as tissue growth, wound healing and immune response. Even if a comprehensive understanding of this motility mode remains elusive, progress has been…

Cell Behavior · Quantitative Biology 2016-05-23 Wieland Marth , Axel Voigt

We address the description of solutes flow with trapping processes in porous media. Starting from a small-scale model for tracer particles trajectories, we derive the corresponding governing equations for the concentration of the mobile and…

Statistical Mechanics · Physics 2010-01-18 Marie-Christine Néel , Andrea Zoia , Maminirina Joelson

The hypothesis of molecular chaos plays the central role in kinetic theory, which provides a closure leading to the Boltzmann equation for quantitative description of classic fluids. Yet how to properly extend it to active systems is still…

We consider a nonlinear coupled discrete-time model of population dynamics. This model describes the movement of populations within a heterogeneous landscape, where the growth of subpopulations are modelled by (possibly different) bounded…

Dynamical Systems · Mathematics 2024-05-08 Blake McGrane-Corrigan , Oliver Mason , Rafael de Andrade Moral

A fractional diffusion equation with advection term is rigorously derived from a kinetic transport model with a linear turning operator, featuring a fat-tailed equilibrium distribution and a small directional bias due to a given vector…

Analysis of PDEs · Mathematics 2015-10-19 Pedro Aceves-Sanchez , Christian Schmeiser

This article concerns an optimal crowd motion control problem in which the crowd features a structure given by its organization into N groups (participants) each one spatially confined in a set. The overall optimal control problem consists…

Optimization and Control · Mathematics 2021-04-21 Tan H. Cao , Nathalie T. Khalil , Boris S. Mordukhovich , Dao Nguyen , Fernando Lobo Pereira

Collective behavior in cellular populations is coordinated by biochemical signaling networks within individual cells. Connecting the dynamics of these intracellular networks to the population phenomena they control poses a considerable…

Biological Physics · Physics 2014-06-27 Allyson E. Sgro , David J. Schwab , Javad Noorbakhsh , Troy Mestler , Pankaj Mehta , Thomas Gregor

Cells and organisms follow aligned structures in their environment, a process that can generate persistent migration paths. Kinetic transport equations are a popular modelling tool for describing biological movements at the mesoscopic…

Cell Behavior · Quantitative Biology 2021-01-13 Nadia Loy , Thomas Hillen , Kevin John Painter

A variety of living and non-living systems exhibit collective motion. From swarm robotics to bacterial swarms, and tissue wound healing to human crowds, examples of collective motion are highly diverse but all of them share the common…

Biological Physics · Physics 2023-07-12 Jonathan E. Dawson , Abdul N. Malmi-Kakkada

We consider the problem of learning the dynamics in the topology of time-evolving point clouds, the prevalent spatiotemporal model for systems exhibiting collective behavior, such as swarms of insects and birds or particles in physics. In…

Machine Learning · Computer Science 2024-11-14 Sebastian Zeng , Florian Graf , Martin Uray , Stefan Huber , Roland Kwitt

We derive a monotonicity property for general, transient flows of a commodity transferred throughout a network, where the flow is characterized by density and mass flux dynamics on the edges with density continuity and mass balance…

Optimization and Control · Mathematics 2016-03-31 Anatoly Zlotnik , Sidhant Misra , Marc Vuffray , Michael Chertkov
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