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Automated detection of mitotic figures in histopathology images is a challenging task: here, we present the different steps that describe the strategy we applied to participate in the MIDOG 2021 competition. The purpose of the competition…
Making histopathology image classifiers robust to a wide range of real-world variability is a challenging task. Here, we describe a candidate deep learning solution for the Mitosis Domain Generalization Challenge 2022 (MIDOG) to address the…
The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitotic figures by pathologists is known to be subject to a strong…
We present a summary of the domain adaptive cascade R-CNN method for mitosis detection of digital histopathology images. By comprehensive data augmentation and adapting existing popular detection architecture, our proposed method has…
Atypical mitotic figures (AMFs) are clinically relevant indicators of abnormal cell division, yet their reliable detection remains challenging due to morphological ambiguity and scanner variability. In this work, we investigated three…
The detection of mitotic figures from different scanners/sites remains an important topic of research, owing to its potential in assisting clinicians with tumour grading. The MItosis DOmain Generalization (MIDOG) challenge aims to test the…
Mitotic figures represent a key histoprognostic feature in tumor pathology, providing crucial insights into tumor aggressiveness and proliferation. However, their identification remains challenging, subject to significant inter-observer…
Mitotic figure detection in histopathology images remains challenging due to significant domain shifts across different scanners, staining protocols, and tissue types. This paper presents our approach for the MIDOG 2025 challenge Track 1,…
This report details our submission to the Mitotic Domain Generalization (MIDOG) 2025 challenge, which addresses the critical task of mitotic figure detection in histopathology for cancer prognostication. Following the "Bitter…
Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient outcome assessment. This task is challenging for algorithms and human experts alike, with deterioration of algorithmic performance under shifts in…
Domain variability is a common bottle neck in developing generalisable algorithms for various medical applications. Motivated by the observation that the domain variability of the medical images is to some extent compact, we propose to…
Deep learning has driven significant advances in mitotic figure analysis within computational pathology. In this paper, we present our approach to the Mitosis Domain Generalization (MIDOG) 2025 Challenge, which consists of two distinct…
Mitotic figure detection remains a challenging task in computational pathology due to domain variability and morphological complexity. This paper describes our participation in the MIDOG 2025 challenge, focusing on robust mitotic figure…
Automated detection and classification of mitotic figures especially distinguishing atypical from normal remain critical challenges in computational pathology. We present MitoDetect++, a unified deep learning pipeline designed for the MIDOG…
Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…
Atypical mitotic figures (AMFs) represent abnormal cell division associated with poor prognosis. Yet their detection remains difficult due to low prevalence, subtle morphology, and inter-observer variability. The MIDOG 2025 challenge…
Counting mitotic figures is time-intensive for pathologists and leads to inter-observer variability. Artificial intelligence (AI) promises a solution by automatically detecting mitotic figures while maintaining decision consistency.…
Assessing the Mitotic Count has a known high degree of intra- and inter-rater variability. Computer-aided systems have proven to decrease this variability and reduce labeling time. These systems, however, are generally highly dependent on…
We propose a two-step domain shift-invariant mitosis cell detection method based on Faster RCNN and a convolutional neural network (CNN). We generate various domain-shifted versions of existing histopathology images using a stain…
This is a write-up of our method submitted to Mitosis Domain Generalization (MIDOG 2021) Challenge held in MICCAI2021 conference.