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Computational pathology and whole-slide image (WSI) analysis are pivotal in cancer diagnosis and prognosis. However, the ultra-high resolution of WSIs presents significant modeling challenges. Recent advancements in pathology foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Honglin Li , Zhongyi Shui , Yunlong Zhang , Chenglu Zhu , Lin Yang

We present a novel weakly-supervised framework for classifying whole slide images (WSIs). WSIs, due to their gigapixel resolution, are commonly processed by patch-wise classification with patch-level labels. However, patch-level labels…

Computer Vision and Pattern Recognition · Computer Science 2022-03-10 Tiange Xiang , Yang Song , Chaoyi Zhang , Dongnan Liu , Mei Chen , Fan Zhang , Heng Huang , Lauren O'Donnell , Weidong Cai

Numerous practical medical problems often involve data that possess a combination of both sparse and non-sparse structures. Traditional penalized regularizations techniques, primarily designed for promoting sparsity, are inadequate to…

Methodology · Statistics 2023-11-10 Shun Yu , Yuehan Yang

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Joohyung Lee , Heejeong Nam , Kwanhyung Lee , Sangchul Hahn

Traditional network embedding primarily focuses on learning a continuous vector representation for each node, preserving network structure and/or node content information, such that off-the-shelf machine learning algorithms can be easily…

Social and Information Networks · Computer Science 2023-01-02 Daokun Zhang , Jie Yin , Xingquan Zhu , Chengqi Zhang

The deep neural network is a research hotspot for histopathological image analysis, which can improve the efficiency and accuracy of diagnosis for pathologists or be used for disease screening. The whole slide pathological image can reach…

Image and Video Processing · Electrical Eng. & Systems 2022-05-09 Tingting Zheng , Weixing chen , Shuqin Li , Hao Quan , Qun Bai , Tianhang Nan , Song Zheng , Xinghua Gao , Yue Zhao , Xiaoyu Cui

Current approaches for classification of whole slide images (WSI) in digital pathology predominantly utilize a two-stage learning pipeline. The first stage identifies areas of interest (e.g. tumor tissue), while the second stage processes…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Marvin Teichmann , Andre Aichert , Hanibal Bohnenberger , Philipp Ströbel , Tobias Heimann

Sparse representation-based classifiers have shown outstanding accuracy and robustness in image classification tasks even with the presence of intense noise and occlusion. However, it has been discovered that the performance degrades…

Computer Vision and Pattern Recognition · Computer Science 2015-12-22 Xiaoxia Sun , Nasser M. Nasrabadi , Trac D. Tran

In big data image/video analytics, we encounter the problem of learning an overcomplete dictionary for sparse representation from a large training dataset, which can not be processed at once because of storage and computational constraints.…

Machine Learning · Computer Science 2014-03-20 Subhadip Mukherjee , Chandra Sekhar Seelamantula

Through spectral unmixing, hyperspectral imaging (HSI) in fluorescence-guided brain tumor surgery has enabled detection and classification of tumor regions invisible to the human eye. Prior unmixing work has focused on determining a minimal…

Image and Video Processing · Electrical Eng. & Systems 2024-02-01 David Black , Benoit Liquet , Sadahiro Kaneko , Antonio Di leva , Walter Stummer , Eric Suero Molina

In this paper, we address the segmentation of tumor subtypes in whole slide images (WSI) by utilizing incomplete label proportions. Specifically, we utilize `partial' label proportions, which give the proportions among tumor subtypes but do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Shinnosuke Matsuo , Daiki Suehiro , Seiichi Uchida , Hiroaki Ito , Kazuhiro Terada , Akihiko Yoshizawa , Ryoma Bise

Hashing has been recognized as an efficient representation learning method to effectively handle big data due to its low computational complexity and memory cost. Most of the existing hashing methods focus on learning the low-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Yujuan Ding , Wai Kueng Wong , Zhihui Lai , Zheng Zhang

Whole slide image (WSI) classification is a crucial problem for cancer diagnostics in clinics and hospitals. A WSI, acquired at gigapixel size, is commonly tiled into patches and processed by multiple-instance learning (MIL) models.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Doanh C. Bui , Jin Tae Kwak

Key properties of brain-inspired hyperdimensional (HD) computing make it a prime candidate for energy-efficient and fast learning in biosignal processing. The main challenge is however to formulate embedding methods that map biosignal…

Signal Processing · Electrical Eng. & Systems 2019-01-01 Michael Hersche , José del R. Millán , Luca Benini , Abbas Rahimi

In this paper, we study weakly-supervised laparoscopic image segmentation with sparse annotations. We introduce a novel Bayesian deep learning approach designed to enhance both the accuracy and interpretability of the model's segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-14 Zhou Zheng , Yuichiro Hayashi , Masahiro Oda , Takayuki Kitasaka , Kensaku Mori

Digital pathology based on whole slide images (WSIs) plays a key role in cancer diagnosis and clinical practice. Due to the high resolution of the WSI and the unavailability of patch-level annotations, WSI classification is usually…

Computer Vision and Pattern Recognition · Computer Science 2023-05-02 Litao Yang , Deval Mehta , Sidong Liu , Dwarikanath Mahapatra , Antonio Di Ieva , Zongyuan Ge

Hyperspectral image (HSI) super-resolution without additional auxiliary image remains a constant challenge due to its high-dimensional spectral patterns, where learning an effective spatial and spectral representation is a fundamental…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Kaiwei Zhang

Delineation of cancerous regions in gigapixel whole slide images (WSIs) is a crucial diagnostic procedure in digital pathology. This process is time-consuming because of the large search space in the gigapixel WSIs, causing chances of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Hsien-Tzu Cheng , Chun-Fu Yeh , Po-Chen Kuo , Andy Wei , Keng-Chi Liu , Mong-Chi Ko , Kuan-Hua Chao , Yu-Ching Peng , Tyng-Luh Liu

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

Computer Vision and Pattern Recognition · Computer Science 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Many algorithms have been developed to solve the inverse problem of coded aperture snapshot spectral imaging (CASSI), i.e., recovering the 3D hyperspectral images (HSIs) from a 2D compressive measurement. In recent years, learning-based…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Yuanhao Cai , Jing Lin , Xiaowan Hu , Haoqian Wang , Xin Yuan , Yulun Zhang , Radu Timofte , Luc Van Gool