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Gigapixel image analysis, particularly for whole slide images (WSIs), often relies on multiple instance learning (MIL). Under the paradigm of MIL, patch image representations are extracted and then fixed during the training of the MIL…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Kunming Tang , Zhiguo Jiang , Jun Shi , Wei Wang , Haibo Wu , Yushan Zheng

Adaptive sparse coding methods learn a possibly overcomplete set of basis functions, such that natural image patches can be reconstructed by linearly combining a small subset of these bases. The applicability of these methods to visual…

Computer Vision and Pattern Recognition · Computer Science 2010-10-19 Koray Kavukcuoglu , Marc'Aurelio Ranzato , Yann LeCun

Survival prediction using whole-slide images (WSIs) is crucial in cancer re-search. Despite notable success, existing approaches are limited by their reliance on sparse slide-level labels, which hinders the learning of discriminative…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Jiaqi Cui , Lu Wen , Yuchen Fei , Bo Liu , Luping Zhou , Dinggang Shen , Yan Wang

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Automatic detection of cancer metastasis from whole slide images (WSIs) is a crucial step for following patient staging and prognosis. Recent convolutional neural network based approaches are struggling with the trade-off between accuracy…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Zixu Zhao , Huangjing Lin , Hao Chen , Pheng-Ann Heng

Subspace clustering is a powerful unsupervised approach for hyperspectral image (HSI) analysis, but its high computational and memory costs limit scalability. Superpixel segmentation can improve efficiency by reducing the number of data…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Xianlu Li , Nicolas Nadisic , Shaoguang Huang , Aleksandra Pizurica

Developing self-supervised learning (SSL) models that can learn universal and transferable representations of H&E gigapixel whole-slide images (WSIs) is becoming increasingly valuable in computational pathology. These models hold the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Guillaume Jaume , Anurag Vaidya , Andrew Zhang , Andrew H. Song , Richard J. Chen , Sharifa Sahai , Dandan Mo , Emilio Madrigal , Long Phi Le , Faisal Mahmood

Hyperspectral imaging (HSI) shows great promise for surgical applications, offering detailed insights into biological tissue differences beyond what the naked eye can perceive. Refined labelling efforts are underway to train vision systems…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Junwen Wang , Oscar Maccormac , William Rochford , Aaron Kujawa , Jonathan Shapey , Tom Vercauteren

Survival prediction based on whole slide images (WSIs) is a challenging task for patient-level multiple instance learning (MIL). Due to the vast amount of data for a patient (one or multiple gigapixels WSIs) and the irregularly shaped…

Computer Vision and Pattern Recognition · Computer Science 2023-07-03 Zhuchen Shao , Yang Chen , Hao Bian , Jian Zhang , Guojun Liu , Yongbing Zhang

Prediction of mRNA gene-expression profiles directly from routine whole-slide images (WSIs) using deep learning models could potentially offer cost-effective and widely accessible molecular phenotyping. While such WSI-based gene-expression…

Genomics · Quantitative Biology 2024-10-03 Fredrik K. Gustafsson , Mattias Rantalainen

Recently, very high-dimensional feature representations, e.g., Fisher Vector, have achieved excellent performance for visual recognition and retrieval. However, these lengthy representations always cause extremely heavy computational and…

Computer Vision and Pattern Recognition · Computer Science 2015-09-17 Li Liu , Mengyang Yu , Ling Shao

We show how perceptual embeddings of the visual system can be constructed at inference-time with no training data or deep neural network features. Our perceptual embeddings are solutions to a weighted least squares (WLS) problem, defined at…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Daniel Severo , Lucas Theis , Johannes Ballé

Vision Transformers (ViTs) and their multi-scale and hierarchical variations have been successful at capturing image representations but their use has been generally studied for low-resolution images (e.g. - 256x256, 384384). For gigapixel…

Computer Vision and Pattern Recognition · Computer Science 2022-06-07 Richard J. Chen , Chengkuan Chen , Yicong Li , Tiffany Y. Chen , Andrew D. Trister , Rahul G. Krishnan , Faisal Mahmood

Within medical imaging, manual curation of sufficient well-labeled samples is cost, time and scale-prohibitive. To improve the representativeness of the training dataset, for the first time, we present an approach to utilize large amounts…

Computer Vision and Pattern Recognition · Computer Science 2019-06-03 Fernando Navarro , Sailesh Conjeti , Federico Tombari , Nassir Navab

Behavioral patterns captured in embeddings learned from interaction data are pivotal across various stages of production recommender systems. However, in the initial retrieval stage, practitioners face an inherent tradeoff between embedding…

Information Retrieval · Computer Science 2026-02-11 Vojtěch Vančura , Martin Spišák , Rodrigo Alves , Ladislav Peška

The difficulty of processing gigapixel whole slide images (WSIs) in clinical microscopy has been a long-standing barrier to implementing computer aided diagnostic systems. Since modern computing resources are unable to perform computations…

Computer Vision and Pattern Recognition · Computer Science 2020-08-13 Sam Maksoud , Kun Zhao , Peter Hobson , Anthony Jennings , Brian Lovell

We propose $\textit{weighted inner product similarity}$ (WIPS) for neural network-based graph embedding. In addition to the parameters of neural networks, we optimize the weights of the inner product by allowing positive and negative…

Machine Learning · Computer Science 2019-06-04 Geewook Kim , Akifumi Okuno , Kazuki Fukui , Hidetoshi Shimodaira

Content-based histopathological image retrieval (CBHIR) has gained attention in recent years, offering the capability to return histopathology images that are content-wise similar to the query one from an established database. However, in…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Xinyu Zhu , Zhiguo Jiang , Kun Wu , Jun Shi , Yushan Zheng

Linear system identification and sparse dictionary learning can both be seen as structured matrix factorization problems. However, these two problems have historically been studied in isolation by the systems theory and machine learning…

Systems and Control · Electrical Eng. & Systems 2026-04-02 Kyle Poe , Uday Kiran Reddy Tadipatri , Benjamin D. Haeffele , Rene Vidal

Recent binary representation learning models usually require sophisticated binary optimization, similarity measure or even generative models as auxiliaries. However, one may wonder whether these non-trivial components are needed to…

Computer Vision and Pattern Recognition · Computer Science 2019-08-27 Yuming Shen , Jie Qin , Jiaxin Chen , Li Liu , Fan Zhu
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