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Principal Component Analysis (PCA) is a method for estimating a subspace given noisy samples. It is useful in a variety of problems ranging from dimensionality reduction to anomaly detection and the visualization of high dimensional data.…

Statistics Theory · Mathematics 2019-06-14 David Hong , Laura Balzano , Jeffrey A. Fessler

Understanding which phenotypic traits are consistently correlated throughout evolution is a highly pertinent problem in modern evolutionary biology. Here, we propose a multivariate phylogenetic latent liability model for assessing the…

Populations and Evolution · Quantitative Biology 2015-09-17 Gabriela B. Cybis , Janet S. Sinsheimer , Trevor Bedford , Alison E. Mather , Philippe Lemey , Marc A. Suchard

We introduce Principal Component Analysis guided Quantile Sampling (PCA QS), a novel sampling framework designed to preserve both the statistical and geometric structure of large scale datasets. Unlike conventional PCA, which reduces…

Methodology · Statistics 2026-01-13 Foo Hui-Mean , Yuan-chin Ivan Chang

Dimension reduction techniques are among the most essential analytical tools in the analysis of high-dimensional data. Generalized principal component analysis (PCA) is an extension to standard PCA that has been widely used to identify…

Probabilistic Component Latent Analysis (PLCA) is a statistical modeling method for feature extraction from non-negative data. It has been fruitfully applied to various research fields of information retrieval. However, the EM-solved…

Methodology · Statistics 2017-03-16 D. Cazau , G. Nuel

Principal component analysis (PCA) is a well-established method commonly used to explore and visualise data. A classical PCA model is the fixed effect model where data are generated as a fixed structure of low rank corrupted by noise. Under…

Methodology · Statistics 2013-05-13 Marie Verbanck , Julie Josse , François Husson

Learning informative representations of phylogenetic tree structures is essential for analyzing evolutionary relationships. Classical distance-based methods have been widely used to project phylogenetic trees into Euclidean space, but they…

Machine Learning · Statistics 2025-02-10 Tianyu Xie , Harry Richman , Jiansi Gao , Frederick A. Matsen , Cheng Zhang

The Phylogenetic Genome Annotator (PGA) is a computer program that enables real-time comparison of 'gene trees' versus 'species trees' obtained from predicted open reading frames of whole genome data. The gene phylogenies are inferred for…

Populations and Evolution · Quantitative Biology 2014-04-04 Paulo Bandiera-Paiva , Marcelo R. S. Briones

Neural operator learning has emerged as a powerful approach for solving partial differential equations (PDEs) in a data-driven manner. However, applying principal component analysis (PCA) to high-dimensional solution fields incurs…

Machine Learning · Computer Science 2025-09-24 Mrigank Dhingra , Romit Maulik , Adil Rasheed , Omer San

The development of high throughput single-cell sequencing technologies now allows the investigation of the population level diversity of cellular transcriptomes. This diversity has shown two faces. First, the expression dynamics (gene to…

Methodology · Statistics 2021-04-10 Ghislain Durif , Laurent Modolo , Jeff E. Mold , Sophie Lambert-Lacroix , Franck Picard

TimeCluster is a visual analytics technique for discovering structure in long multivariate time series by projecting overlapping windows of data into a low-dimensional space. We show that, when Principal Component Analysis (PCA) is chosen…

Machine Learning · Computer Science 2025-09-17 Christian L. Hines , Samuel Spillard , Daniel P. Martin

Principal component analysis (PCA) is a fundamental technique for dimensionality reduction and denoising; however, its application to three-dimensional data with arbitrary orientations -- common in structural biology -- presents significant…

Signal Processing · Electrical Eng. & Systems 2025-10-22 Michael Fraiman , Paulina Hoyos , Tamir Bendory , Joe Kileel , Oscar Mickelin , Nir Sharon , Amit Singer

This is a tutorial and survey paper on factor analysis, probabilistic Principal Component Analysis (PCA), variational inference, and Variational Autoencoder (VAE). These methods, which are tightly related, are dimensionality reduction and…

Machine Learning · Statistics 2022-05-25 Benyamin Ghojogh , Ali Ghodsi , Fakhri Karray , Mark Crowley

Many statistical estimation techniques for high-dimensional or functional data are based on a preliminary dimension reduction step, which consists in projecting the sample $\bX_1, \hdots, \bX_n$ onto the first $D$ eigenvectors of the…

Statistics Theory · Mathematics 2010-04-26 Gérard Biau , André Mas

Principal component analysis (PCA) is a dimensionality reduction method in data analysis that involves diagonalizing the covariance matrix of the dataset. Recently, quantum algorithms have been formulated for PCA based on diagonalizing a…

Quantum Physics · Physics 2022-10-26 Max Hunter Gordon , M. Cerezo , Lukasz Cincio , Patrick J. Coles

Topological Data Analysis (TDA) is a rapidly growing field, which studies methods for learning underlying topological structures present in complex data representations. TDA methods have found recent success in extracting useful geometric…

Methodology · Statistics 2021-03-09 Xiaojun Zheng , Simon Mak , Yao Xie

PCA can be used for rotation invariant features, describing a shape with its $p_{ab}=E[(x_i-E[x_a])(x_b-E[x_b])]$ covariance matrix approximating shape by ellipsoid, allowing for rotation invariants like its traces of powers. However, real…

Computer Vision and Pattern Recognition · Computer Science 2026-01-08 Jarek Duda

Deep autoencoders are often extended with a supervised or adversarial loss to learn latent representations with desirable properties, such as greater predictivity of labels and outcomes or fairness with respects to a sensitive variable.…

Machine Learning · Statistics 2022-01-10 William E. Carson , Austin Talbot , David Carlson

We present a method of dimensional reduction for the general Markov model of sequence evolution on a phylogenetic tree. We show that taking certain linear combinations of the associated random variables (site pattern counts) reduces the…

Populations and Evolution · Quantitative Biology 2016-11-29 Jeremy G Sumner

In this paper, we propose a novel robust Principal Component Analysis (PCA) for high-dimensional data in the presence of various heterogeneities, especially the heavy-tailedness and outliers. A transformation motivated by the characteristic…

Methodology · Statistics 2022-04-05 Lingyu He , Yanrong Yang , Bo Zhang