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Microstructural evolution is a key aspect of understanding and exploiting the structure-property-performance relation of materials. Modeling microstructure evolution usually relies on coarse-grained simulations with evolution principles…

Materials Science · Physics 2020-09-01 Kaiqi Yang , Yifan Cao , Youtian Zhang , Ming Tang , Daniel Aberg , Babak Sadigh , Fei Zhou

In response to a concentration gradient of nutrient, E. coli bacterium modulates the rotational bias of flagellar motors which control its run-and-tumble motion, to migrate towards regions of high nutrient concentration. Presence of…

Cell Behavior · Quantitative Biology 2018-04-04 Subrata Dev , Sakuntala Chatterjee

Embryogenesis is a multiscale process during which developmental symmetry breaking transitions give rise to complex multicellular organisms. Recent advances in high-resolution live-cell microscopy provide unprecedented insights into the…

Biological Physics · Physics 2023-06-27 Nicolas Romeo , Alasdair Hastewell , Alexander Mietke , Jörn Dunkel

Organisms must acquire and use environmental information to guide their behaviors. However, it is unclear whether and how information quantitatively limits behavioral performance. Here, we relate information to behavioral performance in…

Biological Physics · Physics 2023-02-22 Henry H. Mattingly , Keita Kamino , Benjamin B. Machta , Thierry Emonet

Robust physics (e.g., governing equations and laws) discovery is of great interest for many engineering fields and explainable machine learning. A critical challenge compared with general training is that the term and format of governing…

Numerical Analysis · Mathematics 2021-02-15 Zhiming Zhang , Yongming Liu

Deriving governing equations in Electromagnetic (EM) environment based on first principles can be quite tough when there are some unknown sources of noise and other uncertainties in the system. For nonlinear multiple-physics electromagnetic…

Computational Physics · Physics 2019-10-31 Bing Xiong , Haiyang Fu , Feng Xu , Yaqiu Jin

Recent advances in high-resolution imaging techniques and particle-based simulation methods have enabled the precise microscopic characterization of collective dynamics in various biological and engineered active matter systems. In…

Soft Condensed Matter · Physics 2023-02-14 Rohit Supekar , Boya Song , Alasdair Hastewell , Gary P. T. Choi , Alexander Mietke , Jörn Dunkel

Modeling the traffic dynamics is essential for understanding and predicting the traffic spatiotemporal evolution. However, deriving the partial differential equation (PDE) models that capture these dynamics is challenging due to their…

Systems and Control · Electrical Eng. & Systems 2025-05-05 Zihang Wei , Yunlong Zhang , Chenxi Liu , Yang Zhou

We introduce a machine learning approach for extracting fine-grained representations of protein evolution from molecular dynamics datasets. Metastable switching linear dynamical systems extend standard switching models with a…

Machine Learning · Statistics 2016-10-07 Bharath Ramsundar , Vijay S. Pande

In this paper, we present an initial attempt to learn evolution PDEs from data. Inspired by the latest development of neural network designs in deep learning, we propose a new feed-forward deep network, called PDE-Net, to fulfill two…

Numerical Analysis · Mathematics 2018-01-03 Zichao Long , Yiping Lu , Xianzhong Ma , Bin Dong

The study presents a general framework for discovering underlying Partial Differential Equations (PDEs) using measured spatiotemporal data. The method, called Sparse Spatiotemporal System Discovery ($\text{S}^3\text{d}$), decides which…

The bacterium E.Coli swims in a zig-zag manner, in a series of straight runs and tumbles occurring alternately, with the run-durations dependent on the local spatial gradient of chemo-attractants/repellants. This enables the organism to…

Cell Behavior · Quantitative Biology 2008-12-31 Melissa Reneaux , Manoj Gopalakrishnan

The chemotactic network of Escherichia coli has been studied extensively both biophysically and information-theoretically. Nevertheless, the connection between these two aspects is still elusive. In this work, we report such a connection by…

Cell Behavior · Quantitative Biology 2021-03-31 Kento Nakamura , Tetsuya J. Kobayashi

The numerical solution of partial differential equations (PDEs) is challenging because of the need to resolve spatiotemporal features over wide length and timescales. Often, it is computationally intractable to resolve the finest features…

Disordered Systems and Neural Networks · Physics 2019-08-22 Yohai Bar-Sinai , Stephan Hoyer , Jason Hickey , Michael P. Brenner

Chemotaxis is the response of a particle to a gradient in the chemical composition of the environment. While it was originally observed for biological organisms, it is of great interest in the context of synthetic active particles such as…

Soft Condensed Matter · Physics 2017-05-02 Laurens Deprez , Pierre de Buyl

Harnessing data to discover the underlying governing laws or equations that describe the behavior of complex physical systems can significantly advance our modeling, simulation and understanding of such systems in various science and…

Machine Learning · Computer Science 2021-11-17 Zhao Chen , Yang Liu , Hao Sun

We construct a reduced, data-driven, parameter dependent effective Stochastic Differential Equation (eSDE) for electric-field mediated colloidal crystallization using data obtained from Brownian Dynamics Simulations. We use Diffusion Maps…

The realistic modeling intended to quantify precisely some biological mechanisms is a task requiering a lot of a priori knowledge and generally leading to heavy mathematical models. On the other hand, the structure of the classical Machine…

Other Statistics · Statistics 2020-01-09 Hélène Flourent , Emmanuel Frénod , Vincent Sincholle

Learning time-dependent partial differential equations (PDEs) that govern evolutionary observations is one of the core challenges for data-driven inference in many fields. In this work, we propose to capture the essential dynamics of…

Numerical Analysis · Mathematics 2021-09-07 Ricardo A. Delgadillo , Jingwei Hu , Haizhao Yang

In this paper we analyze a system of PDEs recently introduced in [P. Amorim, {\it Modeling ant foraging: a {chemotaxis} approach with pheromones and trail formation}], in order to describe the dynamics of ant foraging. The system is made of…

Analysis of PDEs · Mathematics 2015-05-05 Ricardo Alonso , Paulo Amorim , Thierry Goudon
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