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Modeling sequential patterns from data is at the core of various time series forecasting tasks. Deep learning models have greatly outperformed many traditional models, but these black-box models generally lack explainability in prediction…

Machine Learning · Computer Science 2023-05-23 Yingtao Luo , Chang Xu , Yang Liu , Weiqing Liu , Shun Zheng , Jiang Bian

Partial differential equations (PDEs) are central to describing and modelling complex physical systems that arise in many disciplines across science and engineering. However, in many realistic applications PDE modelling provides an…

Machine Learning · Computer Science 2023-04-04 Nacime Bouziani , David A. Ham

In this paper, we investigate the stochastic evolution equations (SEEs) driven by $\log$-Whittle-Mat$\acute{{\mathrm{e}}}$rn (W-M) random diffusion coefficient field and $Q$-Wiener multiplicative force noise. First, the well-posedness of…

Numerical Analysis · Mathematics 2022-07-05 X. Qi , M. Azaiez , C. Huang , C. Xu

Partial Differential Equations (PDEs) with high dimensionality are commonly encountered in computational physics and engineering. However, finding solutions for these PDEs can be computationally expensive, making model-order reduction…

Machine Learning · Statistics 2023-03-07 Sebastian Kaltenbach , Phaedon-Stelios Koutsourelakis , Petros Koumoutsakos

This review examines the current state of research on microscale cellular changes during the drying of plant-based food materials (PBFM), with particular emphasis on computational modelling approaches. The review addresses the critical need…

Machine Learning · Computer Science 2025-01-17 C. P. Batuwatta-Gamage , H. Jeong , HCP Karunasena , M. A. Karim , C. M. Rathnayaka , Y. T. Gu

Single-particle traces of the diffusive motion of molecules, cells, or animals are by-now routinely measured, similar to stochastic records of stock prices or weather data. Deciphering the stochastic mechanism behind the recorded dynamics…

Statistical Mechanics · Physics 2023-09-14 Henrik Seckler , Janusz Szwabinski , Ralf Metzler

We provide a review of recent advancements in nonlocal continuous models for migration, mainly from the perspective of its involvement in embryonal development and cancer invasion. Particular emphasis is placed on spatial nonlocality…

Analysis of PDEs · Mathematics 2019-11-14 Li Chen , Kevin Painter , Christina Surulescu , Anna Zhigun

Density functional theory (DFT) has become a standard tool for the study of point defects in materials. However, finding the most stable defective structures remains a very challenging task as it involves the solution of a multimodal…

Materials Science · Physics 2020-11-16 Marco Arrigoni , Georg K. H. Madsen

Enzyme is the major workhorse to carry out the diverse cellular functions. It catalyzes the biological reactions with a high specificity, with its topology playing a crucial role. For ecologically safe production of numerous bioproducts…

Biomolecules · Quantitative Biology 2021-06-04 Prabha Sankara Narayanan , Ashish Runthala

Partial Differential Equations (PDEs) describe phenomena ranging from turbulence and epidemics to quantum mechanics and financial markets. Despite recent advances in computational science, solving such PDEs for real-world applications…

Machine Learning · Computer Science 2025-05-19 Lothar Heimbach , Sebastian Kaltenbach , Petr Karnakov , Francis J. Alexander , Petros Koumoutsakos

Mathematical models describing the spatial spreading and invasion of populations of biological cells are often developed in a continuum modelling framework using reaction-diffusion equations. While continuum models based on linear diffusion…

Cellular Automata and Lattice Gases · Physics 2024-01-23 Matthew J Simpson , Keeley M Murphy , Scott W McCue , Pascal R Buenzli

Causal discovery is a data-driven paradigm for analyzing complex systems, while physics-based models, such as ordinary differential equations (ODEs), provide mechanistic structure for real-world dynamical processes. Integrating these…

Machine Learning · Computer Science 2026-05-21 Jianhong Chen , Naichen Shi , Xubo Yue

Many physical processes can be expressed through partial differential equations (PDEs). Real-world measurements of such processes are often collected at irregularly distributed points in space, which can be effectively represented as…

Machine Learning · Computer Science 2025-07-16 Jost Arndt , Utku Isil , Michael Detzel , Wojciech Samek , Jackie Ma

Discovering hidden partial differential equations (PDEs) and operators from data is an important topic at the frontier between machine learning and numerical analysis. This doctoral thesis introduces theoretical results and deep learning…

Numerical Analysis · Mathematics 2022-10-31 Nicolas Boullé

Organisms use specialized sensors to measure their environments, but the fundamental principles that determine their accuracy remain largely unknown. In Escherichia coli chemotaxis, we previously found that gradient-climbing speed is…

Biological Physics · Physics 2025-08-28 Henry H. Mattingly , Keita Kamino , Jude Ong , Rafaela Kottou , Thierry Emonet , Benjamin B. Machta

We propose a model of chemostat where the bacterial population is individually-based, each bacterium is explicitly represented and has a mass evolving continuously over time. The substrate concentration is represented as a conventional…

Probability · Mathematics 2013-11-08 Fabien Campillo , Coralie Fritsch

The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

Machine Learning · Computer Science 2025-12-10 Udesh Habaraduwa , Andrei Lixandru

We study the movement of the living organism in a band form towards the presence of chemical substrate based on a system of partial differential evolution equations. We incorporate the Einstein's method of Brownian motion to deduce the…

Dynamical Systems · Mathematics 2022-02-01 Rahnuma Islam , Akif Ibragimov

We present a discrete model of chemotaxis whereby cells responding to a chemoattractant are seen as individual agents whose movement is described through a set of rules that result in a biased random walk. In order to take into account…

Analysis of PDEs · Mathematics 2020-03-27 Federica Bubba , Tommaso Lorenzi , Fiona R Macfarlane

Immune cells have evolved to recognize and eliminate pathogens, and the efficiency of this process can be measured in a Petri dish. Yet, even if the cells are time-lapse recorded and tracked with high resolution, it is difficult to judge…

Quantitative Methods · Quantitative Biology 2019-06-21 Claus Metzner
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