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The self-assembly of complex structures from engineered subunits is a major goal of nanotechnology, but controlling their size becomes increasingly difficult in larger assemblies. Existing strategies present significant challenges, among…

We outline a basic strategy of how self-propulsion can be used to improve the yield of a typical colloidal self-assembly process. The success of this approach is predicated on the thoughtful design of the colloidal building block as well as…

Soft Condensed Matter · Physics 2016-08-24 S. A. Mallory , A. Cacciuto

We study the self-assembly behaviour of patchy particles with `protein-like' interactions that can be considered as a minimal model for the assembly of viral capsids and other shell-like protein complexes. We thoroughly explore the…

Soft Condensed Matter · Physics 2010-01-21 Alex W. Wilber , Jonathan P. K. Doye , Ard A. Louis , Anna C. F. Lewis

Porous mesophases, where well-defined particle-depleted 'void' spaces are present within a particle-rich background fluid, can be self-assembled from colloidal particles interacting via isotropic pair interactions with competing attractions…

Soft Condensed Matter · Physics 2017-02-16 Beth A. Lindquist , Sayantan Dutta , Ryan B. Jadrich , Delia J. Milliron , Thomas M. Truskett

Understanding the complex self-assembly of biomacromolecules is a major outstanding question. Microtubules are one example of a biopolymer that possesses characteristics quite distinct from standard synthetic polymers that are derived from…

Soft Condensed Matter · Physics 2013-01-10 Shengfeng Cheng , Ankush Aggarwal , Mark J. Stevens

Rational design strategies for self-assembly require a detailed understanding of both the equilibrium state and the assembly kinetics. While the former is starting to be well understood, the latter remains a major theoretical challenge,…

Soft Condensed Matter · Physics 2026-03-03 Maximilian C. Hübl , Carl P. Goodrich

Addressable self-assembly is the formation of a target structure from a set of unique molecular or colloidal building-blocks, each of which occupies a defined location in the target. The requirement that each type of building-block appears…

Soft Condensed Matter · Physics 2019-12-03 Jim Madge , David Bourne , Mark A. Miller

Self-assembly is traditionally described as the process through which an initially disordered system relaxes towards an equilibrium ordered phase only driven by local interactions between its building blocks. However, This definition is too…

Soft Condensed Matter · Physics 2015-06-15 Lorenzo Di Michele , Francesco Varrato , Jurij Kotar , Simon H. Nathan , Giuseppe Foffi , Erika Eiser

Self-assembly in the laboratory can now yield `information-rich' nanostructures in which each component is of a distinct type and has a defined spatial position. Ensuring the thermodynamic stability of such structures requires…

Biological Physics · Physics 2016-03-22 Stephen Whitelam

Complex colloidal cluster morphologies are desirable for the fabrication of advanced materials, such as photonic crystals and meta-materials, and can be formed through evaporation-driven packing. By coupling lattice Boltzmann and discrete…

Soft Condensed Matter · Physics 2026-05-07 Junyu Yang , Abhinav Naga , Xitong Zhang , Halim Kusumaatmaja

In this work we consider the inverse problem of finding guiding pattern shapes that result in desired self-assembly morphologies of block copolymer melts. Specifically, we model polymer self-assembly using Self-Consistent Field Theory and…

Soft Condensed Matter · Physics 2021-12-20 Daniil Bochkov , Frederic Gibou

Inverse methods of statistical mechanics have facilitated the discovery of pair potentials that stabilize a wide variety of targeted lattices at zero temperature. However, such methods are complicated by the need to compare, within the…

Statistical Mechanics · Physics 2016-09-19 Beth A. Lindquist , Ryan B. Jadrich , Thomas M. Truskett

Limited bonding valence, usually accompanied by well-defined directional interactions and selective bonding mechanisms, is nowadays considered among the key ingredients to create complex structures with tailored properties: even though…

Soft Condensed Matter · Physics 2017-10-11 Emanuela Bianchi , Barbara Capone , Ivan Coluzza , Lorenzo Rovigatti , Peter D. J. van Oostrum

Self-assembly of complex and functional materials remains a grand challenge in soft material science. Efficient assembly depends on a delicate balance between thermodynamic and kinetic effects, requiring fine-tuning affinities and…

Soft Condensed Matter · Physics 2024-11-14 Wei-Shao Wei , Anthony Trubiano , Christian Sigl , Stefan Paquay , Hendrik Dietz , Michael F. Hagan , Seth Fraden

Self-assembly, the process by which interacting components form well-defined and often intricate structures, is typically thought of as a spontaneous process arising from equilibrium dynamics. When a system is driven by external…

Statistical Mechanics · Physics 2021-11-12 Shriram Chennakesavalu , Grant M. Rotskoff

Fabrication of diamond structures by self-assembly is a fundamental challenge in making three-dimensional photonic crystals. We simulate a system of model hard particles with attractive patches and show that they can self-assemble into a…

Statistical Mechanics · Physics 2012-01-18 Zhenli Zhang , Aaron S. Keys , Ting Chen , Sharon C. Glotzer

Flexibility governs the many properties of materials and is crucial for the function of proteins and biopolymers. However, how the self-assembly of flexibly bonded particles can lead to larger structures with global reconfigurability is…

Soft Condensed Matter · Physics 2024-06-28 Yogesh Shelke , Daniel J. G. Pearce , Daniela J. Kraft

We show that chiral symmetry can be broken spontaneously in one-component systems with isotropic interactions, i.e. many-particle systems having maximal a priori symmetry. This is achieved by designing isotropic potentials that lead to…

Materials Science · Physics 2012-05-16 Erik Edlund , Oskar Lindgren , Martin Nilsson Jacobi

The development of new materials typically involves a process of trial and error, guided by insights from past experimental and theoretical findings. The inverse design approach for soft-matter systems has the potential to optimize specific…

Self-assembly of colloidal particles is a promising avenue to control the shape and dynamics of larger aggregates. However, achieving the necessary fine control over the dynamics and specificity of the bonds between such particles remains a…

Soft Condensed Matter · Physics 2024-09-26 Muraleedharapai Mayarani , Justine Laurent , Martin Lenz , Olivia du Roure , Julien Heuvingh