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Confocal laser scanning microscopy (CLSM) stands out as one of the most widely used microscopy techniques, thanks to its three-dimensional imaging capability and its sub-diffraction spatial resolution, achieved through the closure of a…

The last two decades experimentally affirmed the quantum nature of free electron wavepackets by the rapid development of transmission electron microscopes into ultrafast, quantum-coherent systems. In particular, ultrafast electron pulses…

Optics · Physics 2022-09-30 Roy Shiloh , Tomas Chlouba , Peter Hommelhoff

Comprehensive, synapse-resolution imaging of the brain will be crucial for understanding neuronal computations and function. In connectomics, this has been the sole purview of volume electron microscopy (EM), which entails an excruciatingly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Yicong Li , Yaron Meirovitch , Aaron T. Kuan , Jasper S. Phelps , Alexandra Pacureanu , Wei-Chung Allen Lee , Nir Shavit , Lu Mi

The alignment of serial-section electron microscopy (ssEM) images is critical for efforts in neuroscience that seek to reconstruct neuronal circuits. However, each ssEM plane contains densely packed structures that vary from one section to…

Computer Vision and Pattern Recognition · Computer Science 2017-12-06 Inwan Yoo , David G. C. Hildebrand , Willie F. Tobin , Wei-Chung Allen Lee , Won-Ki Jeong

The scanning electron microscopy (SEM) is probably one the most fascinating examination approach that has been used since more than two decades to detailed inspection of micro scale objects. Most of the scanning electron microscopes could…

Computer Vision and Pattern Recognition · Computer Science 2016-02-18 Wichai Shanklin

A simple, yet general, formalism for the optimized linear combination of astrophysical images is constructed and demonstrated. The formalism allows the user to combine multiple undersampled images to provide oversampled output at high…

Instrumentation and Methods for Astrophysics · Physics 2015-05-28 Barnaby Rowe , Christopher Hirata , Jason Rhodes

Extended source effects can be seen in gravitational lensing events when sources cross critical lines. Those events probe the stellar intensity profile and could be used to measure limb darkening coefficients to test stellar model…

Instrumentation and Methods for Astrophysics · Physics 2019-08-14 Hans J. Witt , F. Atrio-Barandela

Independently from electron beam based procedures, photon beam based diagnostics is an alternative way for alignment and commissioning of the numerous undulator cells in a high-gain short-wavelength free-electron laser (FEL). In this paper,…

Accelerator Physics · Physics 2014-10-15 Chao Feng , Haixiao Deng , Manzhou Zhang , Shunqiang Tian , Meng Zhang , Bo Liu , Zhimin Dai

Electroluminescence (EL) imaging is widely used to detect defects in photovoltaic (PV) modules, and machine learning methods have been applied to enable large-scale analysis of EL images. However, existing methods cannot assign multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ojas Sanghi , Norman Jost , Benjamin G. Pierce , Emma Cooper , Isaiah H. Deane , Jennifer L. Braid

Electromagnetic (EM) imaging is widely applied in sensing for security, biomedicine, geophysics, and various industries. It is an ill-posed inverse problem whose solution is usually computationally expensive. Machine learning (ML)…

Computational Physics · Physics 2022-07-27 Rui Guo , Tianyao Huang , Maokun Li , Haiyang Zhang , Yonina C. Eldar

We propose TG-LMM (Text-Guided Large Multi-Modal Model), a novel approach that leverages textual descriptions of organs to enhance segmentation accuracy in medical images. Existing medical image segmentation methods face several challenges:…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Yihao Zhao , Enhao Zhong , Cuiyun Yuan , Yang Li , Man Zhao , Chunxia Li , Jun Hu , Chenbin Liu

Circular dichroism spectroscopy is an essential technique for understanding molecular structure and magnetic materials, but spatial resolution is limited by the wavelength of light, and sensitivity sufficient for single-molecule…

Low-light image enhancement is an important task in computer vision, essential for improving the visibility and quality of images captured in non-optimal lighting conditions. Inadequate illumination can lead to significant information loss…

Computer Vision and Pattern Recognition · Computer Science 2025-05-15 Ezequiel Perez-Zarate , Oscar Ramos-Soto , Chunxiao Liu , Diego Oliva , Marco Perez-Cisneros

Electron channeling contrast imaging (ECCI) is a scanning electron microscopy (SEM) based technique that enables bulk-sample characterization of crystallographic defects (e.g. dislocations, stacking faults, low angle boundaries). Despite…

Like other experimental techniques, X-ray Photon Correlation Spectroscopy is subject to various kinds of noise. Random and correlated fluctuations and heterogeneities can be present in a two-time correlation function and obscure the…

Deep learning methods have played a more and more important role in hyperspectral image classification. However, the general deep learning methods mainly take advantage of the information of sample itself or the pairwise information between…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Zhiqiang Gong , Weidong Hu , Xiaoyong Du , Ping Zhong , Panhe Hu

Semantic segmentation of electron microscopy (EM) images of biological samples remains a challenge in the life sciences. EM data captures details of biological structures, sometimes with such complexity that even human observers can find it…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Sheida Rahnamai Kordasiabi , Damian Dalle Nogare , Florian Jug

Dual-energy computed tomography (DECT) is of great significance for clinical practice due to its huge potential to provide material-specific information. However, DECT scanners are usually more expensive than standard single-energy CT…

Medical Physics · Physics 2020-06-02 Tianling Lyu , Zhan Wu , Yikun Zhang , Yang Chen , Lei Xing , Wei Zhao

Characterization of materials via electron micrographs is an important and challenging task in several materials processing industries. Classification of electron micrographs is complex due to the high intra-class dissimilarity, high…

Computer Vision and Pattern Recognition · Computer Science 2024-09-11 Sakhinana Sagar Srinivas , Rajat Kumar Sarkar , Venkataramana Runkana

Confocal microscopy has long been a cornerstone technique for visualizing complex interactions and processes within cellular structures. However, achieving super-resolution imaging of multiple organelles and their interactions…

Optics · Physics 2025-08-19 Qinglin Chen , Luwei Wang , Jia Li , Dan Shao , Xiaoyu Weng , Liwei Liu , Dayong Jin , Junle Qu
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