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The spatial resolution of images of living samples obtained by fluorescence microscopes is physically limited due to the diffraction of visible light, which makes the study of entities of size less than the diffraction barrier (around 200…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Vasiliki Stergiopoulou , Subhadip Mukherjee , Luca Calatroni , Laure Blanc-Féraud

Although defocus can be used to generate partial phase contrast in transmission electron microscope images, cryo-electron microscopy (cryo-EM) can be further improved by the development of phase plates which increase contrast by applying a…

Quantitative Methods · Quantitative Biology 2024-03-14 Jeremy J. Axelrod , Jessie T. Zhang , Petar N. Petrov , Robert M. Glaeser , Holger Mueller

Low-electron-dose observation is indispensable for observing various samples using a transmission electron microscope; consequently, image processing has been used to improve transmission electron microscopy (TEM) images. To apply such…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Hiroyasu Katsuno , Yuki Kimura , Tomoya Yamazaki , Ichigaku Takigawa

We demonstrate a multi-beam scanning transmission electron microscopy (STEM) imaging that integrates down-sampling with super-resolution image reconstruction via a compressive sensing framework. A custom condenser aperture with six randomly…

Instrumentation and Detectors · Physics 2026-03-19 Akira Yasuhara , Takumi Sannomiya , Ryoichi Horisaki

Recent advancements in Large Vision-Language Models (LVLMs) have significantly expanded their utility in tasks like image captioning and visual question answering. However, they still struggle with object hallucination, where models…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yeongjae Cho , Keonwoo Kim , Taebaek Hwang , Sungzoon Cho

Multi-exposure correction technology is essential for restoring images affected by insufficient or excessive lighting, enhancing the visual experience by improving brightness, contrast, and detail richness. However, current multi-exposure…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Ming Zhao , Pingping Liu , Tongshun Zhang , Zhe Zhang

Low-light image enhancement is challenging in that it needs to consider not only brightness recovery but also complex issues like color distortion and noise, which usually hide in the dark. Simply adjusting the brightness of a low-light…

Image and Video Processing · Electrical Eng. & Systems 2020-03-17 Feifan Lv , Yu Li , Feng Lu

Four-dimensional Scanning Transmission Electron Microscopy (4D STEM) with data acquired using a defocused electron probe is a promising tool for characterising complex biological specimens and materials through a phase retrieval process…

Signal Processing · Electrical Eng. & Systems 2025-05-15 Amirafshar Moshtaghpour , Angus I. Kirkland

Electron Microscopy (EM) image (or volume) segmentation has become significantly important in recent years as an instrument for connectomics. This paper proposes a novel agglomerative framework for EM segmentation. In particular, given an…

Computer Vision and Pattern Recognition · Computer Science 2015-06-09 Toufiq Parag , Anirban Chakraborty , Stephen Plaza , Lou Scheffer

Accurate lesion classification in Wireless Capsule Endoscopy (WCE) images is vital for early diagnosis and treatment of gastrointestinal (GI) cancers. However, this task is confronted with challenges like tiny lesions and background…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Kunpeng Qiu , Zhiying Zhou , Yongxin Guo

This paper presents a novel network structure with illumination-aware gamma correction and complete image modelling to solve the low-light image enhancement problem. Low-light environments usually lead to less informative large-scale dark…

Computer Vision and Pattern Recognition · Computer Science 2023-08-17 Yinglong Wang , Zhen Liu , Jianzhuang Liu , Songcen Xu , Shuaicheng Liu

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

One popular approach for blind deconvolution is to formulate a maximum a posteriori (MAP) problem with sparsity priors on the gradients of the latent image, and then alternatingly estimate the blur kernel and the latent image. While several…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Sunghyun Cho , Seungyong Lee

Unlike single image task, stereo image enhancement can use another view information, and its key stage is how to perform cross-view feature interaction to extract useful information from another view. However, complex noise in low-light…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Minghua Zhao , Xiangdong Qin , Shuangli Du , Xuefei Bai , Jiahao Lyu , Yiguang Liu

Four-dimensional scanning transmission electron microscopy (4D-STEM) of local atomic diffraction patterns is emerging as a powerful technique for probing intricate details of atomic structure and atomic electric fields. However, efficient…

Image and Video Processing · Electrical Eng. & Systems 2019-01-15 Xin Li , Ondrej E. Dyck , Mark P. Oxley , Andrew R. Lupini , Leland McInnes , John Healy , Stephen Jesse , Sergei V. Kalinin

The synergy between free electrons and light has recently been leveraged to reach an impressive degree of simultaneous spatial and spectral resolution, enabling applications in microscopy and quantum optics. However, the required…

Recording atomic-resolution transmission electron microscopy (TEM) images is becoming increasingly routine. A new bottleneck is then analyzing this information, which often involves time-consuming manual structural identification. We have…

Scanning Electron Microscopes (SEMs) are widely renowned for their ability to analyze the surface structures of microscopic objects, offering the capability to capture highly detailed, yet only grayscale, images. To create more expressive…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Takuma Nishimura , Andreea Dogaru , Martin Oeggerli , Bernhard Egger

Monochromators are an essential component in electron microscopy and spectroscopy for enhancing the spatial and energy resolution. However, its adoption in scanning electron microscopes remains limited because of its high cost and…

Instrumentation and Detectors · Physics 2025-10-27 M. J. Adriaans , J. P. Hoogenboom , A. Mohammadi-Gheidari

Light and matter share fundamental statistical properties, yet the experimental probes of quantum optics and many-body physics have largely evolved along separate trajectories. While many-body physics explores emergent collective phenomena,…

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