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Predicting whether someone with mild cognitive impairment (MCI) will progress to Alzheimer's disease (AD) is crucial in the early stages of neurodegeneration. This uncertainty limits enrollment in clinical trials and delays urgent…

Neurons and Cognition · Quantitative Biology 2026-03-30 Ishaan Cherukuri

Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders worldwide. As it progresses, it leads to the deterioration of cognitive functions. Since AD is irreversible, early diagnosis is crucial for managing its…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Mahdieh Behjat Khatooni , Mohsen Soryani

Alzheimer's disease (AD) is an irreversible, progressive neuro degenerative disorder that slowly destroys memory and thinking skills and eventually, the ability to carry out the simplest tasks. In this paper, a deep neural network based…

Image and Video Processing · Electrical Eng. & Systems 2021-05-17 Manu Subramoniam , Aparna T. R. , Anurenjan P. R. , Sreeni K. G

Understanding how large-scale functional brain networks reorganize during cognitive decline remains a central challenge in neuroimaging. While recent self-supervised models have shown promise for learning representations from resting-state…

Machine Learning · Computer Science 2026-03-03 Karanpartap Singh , Adam Turnbull , Mohammad Abbasi , Kilian Pohl , Feng Vankee Lin , Ehsan Adeli

Increasing effort in brain image analysis has been dedicated to early diagnosis of Alzheimer's disease (AD) based on neuroimaging data. Most existing studies have been focusing on binary classification problems, e.g., distinguishing AD…

Computer Vision and Pattern Recognition · Computer Science 2017-09-14 Hongming Li , Mohamad Habes , Yong Fan

The state-of-the-art deep learning methods have demonstrated impressive performance in segmentation tasks. However, the success of these methods depends on a large amount of manually labeled masks, which are expensive and time-consuming to…

Image and Video Processing · Electrical Eng. & Systems 2021-12-06 Shuqiang Wang , Zhuo Chen , Wen Yu , Baiying Lei

Machine learning models are known to be vulnerable to adversarial perturbations in the input domain, causing incorrect predictions. Inspired by this phenomenon, we explore the feasibility of manipulating EEG-based Motor Imagery (MI) Brain…

Cryptography and Security · Computer Science 2022-11-21 Bibek Upadhayay , Vahid Behzadan

Brain graphs (i.e, connectomes) constructed from medical scans such as magnetic resonance imaging (MRI) have become increasingly important tools to characterize the abnormal changes in the human brain. Due to the high acquisition cost and…

Machine Learning · Computer Science 2021-05-07 Alaa Bessadok , Mohamed Ali Mahjoub , Islem Rekik

A common neurodegenerative disease, Alzheimer's disease requires a precise diagnosis and efficient treatment, particularly in light of escalating healthcare expenses and the expanding use of artificial intelligence in medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2025-05-21 Soyabul Islam Lincoln , Mirza Mohd Shahriar Maswood

Effective connectivity estimation plays a crucial role in understanding the interactions and information flow between different brain regions. However, the functional time series used for estimating effective connectivity is derived from…

Image and Video Processing · Electrical Eng. & Systems 2024-05-29 Qiankun Zuo , Ling Chen , Yanyan Shen , Michael Kwok-Po Ng , Baiying Lei , Shuqiang Wang

Compressed sensing (CS) leverages the sparsity prior to provide the foundation for fast magnetic resonance imaging (fastMRI). However, iterative solvers for ill-posed problems hinder their adaption to time-critical applications. Moreover,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-16 Jingshuai Liu , Mehrdad Yaghoobi

In this paper, we provide an extensive overview of machine learning techniques applied to structural magnetic resonance imaging (MRI) data to obtain clinical classifiers. We specifically address practical problems commonly encountered in…

Quantitative Methods · Quantitative Biology 2018-08-20 José María Mateos-Pérez , Mahsa Dadar , María Lacalle-Aurioles , Yasser Iturria-Medina , Yashar Zeighami , Alan C. Evans

Magnetic Resonance Imaging (MRI) is a vital modality for gaining precise anatomical information, and it plays a significant role in medical imaging for diagnosis and therapy planning. Image synthesis problems have seen a revolution in…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Drici Mourad , Kazeem Oluwakemi Oseni

We propose a method to predict the subject-specific longitudinal progression of brain structures extracted from baseline MRI, and evaluate its performance on Alzheimer's disease data. The disease progression is modeled as a trajectory on a…

Computer Vision and Pattern Recognition · Computer Science 2017-11-27 Alexandre Bône , Maxime Louis , Alexandre Routier , Jorge Samper , Michael Bacci , Benjamin Charlier , Olivier Colliot , Stanley Durrleman

This paper proposes a novel approach of integrating different neuroimaging techniques to characterize an autistic brain. Different techniques like EEG, fMRI and DTI have traditionally been used to find biomarkers for autism, but there have…

Multiple modalities of biomarkers have been proved to be very sensitive in assessing the progression of Alzheimer's disease (AD), and using these modalities and machine learning algorithms, several approaches have been proposed to assist in…

Machine Learning · Statistics 2017-12-05 Chen Fang , Panuwat Janwattanapong , Chunfei Li , Malek Adjouadi

Graph neural network (GNN) models are increasingly being used for the classification of electroencephalography (EEG) data. However, GNN-based diagnosis of neurological disorders, such as Alzheimer's disease (AD), remains a relatively…

Neurons and Cognition · Quantitative Biology 2023-12-21 Dominik Klepl , Fei He , Min Wu , Daniel J. Blackburn , Ptolemaios G. Sarrigiannis

Alzheimer's Disease (AD) is a non-curable progressive neurodegenerative disorder that affects the human brain, leading to a decline in memory, cognitive abilities, and eventually, the ability to carry out daily tasks. Manual diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-13 Santanu Roy , Archit Gupta , Shubhi Tiwari , Palak Sahu

Magnetic Resonance Imaging (MRI) of the brain can come in the form of different modalities such as T1-weighted and Fluid Attenuated Inversion Recovery (FLAIR) which has been used to investigate a wide range of neurological disorders.…

Machine Learning · Computer Science 2019-12-11 Harrison Nguyen , Simon Luo , Fabio Ramos

Alzheimer's disease (AD) is one of the most common public health issues the world is facing today. This disease has a high prevalence primarily in the elderly accompanying memory loss and cognitive decline. AD detection is a challenging…

Image and Video Processing · Electrical Eng. & Systems 2022-04-04 Zahraa Sh. Aaraji , Hawraa H. Abbas