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Structural magnetic resonance imaging (sMRI) is widely used for brain neurological disease diagnosis; while longitudinal MRIs are often collected to monitor and capture disease progression, as clinically used in diagnosing Alzheimer's…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Qiuhui Chen , Yi Hong

Predicting Mild Cognitive Impairment (MCI) is currently a challenge as existing diagnostic criteria rely on neuropsychological examinations. Automated Machine Learning (ML) models that are trained on verbal utterances of MCI patients can…

Computation and Language · Computer Science 2015-12-11 Sylvester Olubolu Orimaye , Kah Yee Tai , Jojo Sze-Meng Wong , Chee Piau Wong

Neuroimaging data, particularly from techniques like MRI or PET, offer rich but complex information about brain structure and activity. To manage this complexity, latent representation models - such as Autoencoders, Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 C. Vázquez-García , F. J. Martínez-Murcia , F. Segovia Román , Juan M. Górriz

We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of…

Neurons and Cognition · Quantitative Biology 2020-06-03 Yunlong Nie , Eugene Opoku , Laila Yasmin , Yin Song , Jie Wang , Sidi Wu , Vanessa Scarapicchia , Jodie Gawryluk , Liangliang Wang , Jiguo Cao , Farouk S. Nathoo

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang

This work validates the generalizability of MRI-based classification of Alzheimer's disease (AD) patients and controls (CN) to an external data set and to the task of prediction of conversion to AD in individuals with mild cognitive…

Brain network provides important insights for the diagnosis of many brain disorders, and how to effectively model the brain structure has become one of the core issues in the domain of brain imaging analysis. Recently, various computational…

Neurons and Cognition · Quantitative Biology 2022-12-02 Zhengwang Xia , Tao Zhou , Saqib Mamoon , Amani Alfakih , Jianfeng Lu

The cross-subject application of EEG-based brain-computer interface (BCI) has always been limited by large individual difference and complex characteristics that are difficult to perceive. Therefore, it takes a long time to collect the…

Machine Learning · Computer Science 2021-02-10 Yonghao Song , Lie Yang , Xueyu Jia , Longhan Xie

Identifying the key microstructure representations is crucial for Computational Materials Design (CMD). However, existing microstructure characterization and reconstruction (MCR) techniques have limitations to be applied for materials…

Materials Science · Physics 2019-01-07 Zijiang Yang , Xiaolin Li , L. Catherine Brinson , Alok N. Choudhary , Wei Chen , Ankit Agrawal

Current neuroimaging techniques provide paths to investigate the structure and function of the brain in vivo and have made great advances in understanding Alzheimer's disease (AD). However, the group-level analyses prevalently used for…

Quantitative Methods · Quantitative Biology 2021-05-31 Nanyan Zhu , Chen Liu , Xinyang Feng , Dipika Sikka , Sabrina Gjerswold-Selleck , Scott A. Small , Jia Guo

In recent years, deep learning-based feature representation methods have shown a promising impact in electroencephalography (EEG)-based brain-computer interface (BCI). Nonetheless, owing to high intra- and inter-subject variabilities, many…

Machine Learning · Computer Science 2020-08-24 Eunjin Jeon , Wonjun Ko , Jee Seok Yoon , Heung-Il Suk

The field of neuroscience is experiencing rapid growth in the complexity and quantity of the recorded neural activity allowing us unprecedented access to its dynamics in different brain areas. The objective of this work is to discover…

Simulating images representative of neurodegenerative diseases is important for predicting patient outcomes and for validation of computational models of disease progression. This capability is valuable for secondary prevention clinical…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Daniele Ravi , Daniel C. Alexander , Neil P. Oxtoby

Functional magnetic resonance imaging (fMRI) is widely used for studying and diagnosing brain disorders, with functional connectivity (FC) matrices providing powerful representations of large-scale neural interactions. However, existing…

Tissues and Organs · Quantitative Biology 2026-04-17 Qianyu Chen , Shujian Yu

MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…

Machine Learning · Computer Science 2022-05-18 Haoteng Tang , Xiyao Fu , Lei Guo , Yalin Wang , Scott Mackin , Olusola Ajilore , Alex Leow , Paul Thompson , Heng Huang , Liang Zhan

Mild cognitive impairment (MCI) is characterized by subtle changes in cognitive functions, often associated with disruptions in brain connectivity. The present study introduces a novel fine-grained analysis to examine topological…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Ninad Aithal , Debanjali Bhattacharya , Neelam Sinha , Thomas Gregor Issac

The estimation of sparse hierarchical components reflecting patterns of the brain's functional connectivity from rsfMRI data can contribute to our understanding of the brain's functional organization, and can lead to biomarkers of diseases.…

Machine Learning · Computer Science 2021-04-22 Dushyant Sahoo , Christos Davatzikos

Several works based on Generative Adversarial Networks (GAN) have been recently proposed to predict a set of medical images from a single modality (e.g, FLAIR MRI from T1 MRI). However, such frameworks are primarily designed to operate on…

Machine Learning · Computer Science 2020-09-24 Alaa Bessadok , Mohamed Ali Mahjoub , Islem Rekik

Collecting and accessing a large amount of medical data is very time-consuming and laborious, not only because it is difficult to find specific patients but also because it is required to resolve the confidentiality of a patient's medical…

Sound · Computer Science 2021-03-04 Junghyun Koo , Jie Hwan Lee , Jaewoo Pyo , Yujin Jo , Kyogu Lee

It is of great significance to apply deep learning for the early diagnosis of Alzheimer's Disease (AD). In this work, a novel tensorizing GAN with high-order pooling is proposed to assess Mild Cognitive Impairment (MCI) and AD. By…

Machine Learning · Computer Science 2020-08-04 Wen Yu , Baiying Lei , Michael K. Ng , Albert C. Cheung , Yanyan Shen , Shuqiang Wang