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Selectivity estimation aims at estimating the number of database objects that satisfy a selection criterion. Answering this problem accurately and efficiently is essential to many applications, such as density estimation, outlier detection,…

Databases · Computer Science 2021-05-28 Yaoshu Wang , Chuan Xiao , Jianbin Qin , Rui Mao , Onizuka Makoto , Wei Wang , Rui Zhang , Yoshiharu Ishikawa

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Ensemble models often achieve higher accuracy than single learners, but their ability to maintain small generalization gaps is not always well understood. This study examines how ensembles balance accuracy and overfitting across four…

Machine Learning · Computer Science 2025-12-08 Zubair Ahmed Mohammad

Large Language Models (LLMs) are unable to reliably reason about specific physical systems. Attempts to imbue LLMs with knowledge of the necessary physics concepts have shown great promise, but explainability and validation remain open…

Artificial Intelligence · Computer Science 2026-05-22 Sean Memery , Kartic Subr

This paper demonstrates how to construct ensembles of spiking neural networks producing state-of-the-art results, achieving classification accuracies of 98.71%, 100.0%, and 99.09%, on the MNIST, NMNIST and DVS Gesture datasets respectively.…

Neural and Evolutionary Computing · Computer Science 2021-09-07 Georgiana Neculae , Oliver Rhodes , Gavin Brown

Multiomics data fusion integrates diverse data modalities, ranging from transcriptomics to proteomics, to gain a comprehensive understanding of biological systems and enhance predictions on outcomes of interest related to disease phenotypes…

Quantitative Methods · Quantitative Biology 2023-08-04 Daisy Yi Ding , Xiaotao Shen , Michael Snyder , Robert Tibshirani

The study of healthy brain development helps to better understand the brain transformation and brain connectivity patterns which happen during childhood to adulthood. This study presents a sparse machine learning solution across whole-brain…

Machine Learning · Computer Science 2019-04-03 Peyman Hosseinzadeh Kassani , Alexej Gossmann , Yu-Ping Wang

This paper studies simultaneous feature selection and extraction in supervised and unsupervised learning. We propose and investigate selective reduced rank regression for constructing optimal explanatory factors from a parsimonious subset…

Methodology · Statistics 2016-10-27 Yiyuan She

Ensemble learning is a mainstay in modern data science practice. Conventional ensemble algorithms assign to base models a set of deterministic, constant model weights that (1) do not fully account for individual models' varying accuracy…

Methodology · Statistics 2019-04-02 Jeremiah Zhe Liu , John Paisley , Marianthi-Anna Kioumourtzoglou , Brent A. Coull

Multi-label classification (MLC) is an ML task of predictive modeling in which a data instance can simultaneously belong to multiple classes. MLC is increasingly gaining interest in different application domains such as text mining,…

Machine Learning · Computer Science 2022-11-22 Ana Kostovska , Carola Doerr , Sašo Džeroski , Dragi Kocev , Panče Panov , Tome Eftimov

We present an integer programming framework to build accurate and interpretable discrete linear classification models. Unlike existing approaches, our framework is designed to provide practitioners with the control and flexibility they need…

Methodology · Statistics 2014-10-03 Berk Ustun , Cynthia Rudin

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

General regression and classification models are constructed as linear combinations of simple rules derived from the data. Each rule consists of a conjunction of a small number of simple statements concerning the values of individual input…

Applications · Statistics 2008-11-12 Jerome H. Friedman , Bogdan E. Popescu

The use of machine learning algorithms in finance, medicine, and criminal justice can deeply impact human lives. As a consequence, research into interpretable machine learning has rapidly grown in an attempt to better control and fix…

Machine Learning · Computer Science 2021-02-02 Thibaut Vidal , Toni Pacheco , Maximilian Schiffer

Machine learning (ML) can be used to construct surrogate models for the fast prediction of a property of interest. ML can thus be applied to chemical projects, where the usual experimentation or calculation techniques can take hours or days…

Despite the wealth of single-cell multi-omics data, it remains challenging to predict the consequences of novel genetic and chemical perturbations in the human body. It requires knowledge of molecular interactions at all biological levels,…

Artificial Intelligence · Computer Science 2025-01-22 You Wu , Lei Xie

We present a new subspace-based method to construct probabilistic models for high-dimensional data and highlight its use in anomaly detection. The approach is based on a statistical estimation of probability density using densities of…

Machine Learning · Computer Science 2021-08-16 Cetin Savkli , Catherine Schwartz

In medical risk modeling, typical data are "scarce": they have relatively small number of training instances (N), censoring, and high dimensionality (M). We show that the problem may be effectively simplified by reducing it to bipartite…

Machine Learning · Computer Science 2012-01-31 Marina Sapir

Medical imaging diagnosis increasingly relies on Machine Learning (ML) models. This is a task that is often hampered by severely imbalanced datasets, where positive cases can be quite rare. Their use is further compromised by their limited…

Machine Learning · Computer Science 2024-01-26 Yumnah Hasan , Allan de Lima , Fatemeh Amerehi , Darian Reyes Fernandez de Bulnes , Patrick Healy , Conor Ryan

Open-set object recognition aims to identify if an object is from a class that has been encountered during training or not. To perform open-set object recognition accurately, a key challenge is how to reduce the reliance on…

Computer Vision and Pattern Recognition · Computer Science 2023-12-22 Haoxuan Qu , Xiaofei Hui , Yujun Cai , Jun Liu