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We propose a virtual staining methodology based on Generative Adversarial Networks to map histopathology images of breast cancer tissue from H&E stain to PHH3 and vice versa. We use the resulting synthetic images to build Convolutional…

Image and Video Processing · Electrical Eng. & Systems 2020-03-18 Caner Mercan , Germonda Reijnen-Mooij , David Tellez Martin , Johannes Lotz , Nick Weiss , Marcel van Gerven , Francesco Ciompi

Deep learning techniques have successfully been employed in numerous computer vision tasks including image segmentation. The techniques have also been applied to medical image segmentation, one of the most critical tasks in computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 Titinunt Kitrungrotsakul , Iwamoto Yutaro , Lanfen Lin , Ruofeng Tong , Jingsong Li , Yen-Wei Chen

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

Computer Vision and Pattern Recognition · Computer Science 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

Training deep networks with limited labeled data while achieving a strong generalization ability is key in the quest to reduce human annotation efforts. This is the goal of semi-supervised learning, which exploits more widely available…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Daiqing Li , Junlin Yang , Karsten Kreis , Antonio Torralba , Sanja Fidler

Cloud removal plays a crucial role in enhancing remote sensing image analysis, yet accurately reconstructing cloud-obscured regions remains a significant challenge. Recent advancements in generative models have made the generation of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Wanli Ma , Oktay Karakus , Paul L. Rosin

Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state…

Computer Vision and Pattern Recognition · Computer Science 2022-02-22 Suvidha Tripathi , Satish Kumar Singh

Deep learning models can generate virtual immunohistochemistry (IHC) stains from hematoxylin and eosin (H&E) images, offering a scalable and low-cost alternative to laboratory IHC. However, reliable evaluation of image quality remains a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-07 Tushar Kataria , Shikha Dubey , Mary Bronner , Jolanta Jedrzkiewicz , Ben J. Brintz , Shireen Y. Elhabian , Beatrice S. Knudsen

Deep learning based models, generally, require a large number of samples for appropriate training, a requirement that is difficult to satisfy in the medical field. This issue can usually be avoided with a proper initialization of the…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Taibou Birgui Sekou , Moncef Hidane , Julien Olivier , Hubert Cardot

Immunohistochemistry (IHC) plays a crucial role in pathology as it detects the over-expression of protein in tissue samples. However, there are still fewer machine learning model studies on IHC's impact on accurate cancer grading. We…

Computer Vision and Pattern Recognition · Computer Science 2024-05-15 Jun Wang , Yu Mao , Yufei Cui , Nan Guan , Chun Jason Xue

Leveraging quantum computing's intrinsic properties to enhance machine learning has shown promise, with quantum generative adversarial networks (QGANs) demonstrating benefits in data generation. However, the application of QGANs to complex…

Quantum Physics · Physics 2024-11-26 Xue Yang , Rigui Zhou , ShiZheng Jia , YaoChong Li , Jicheng Yan , ZhengYu Long , Wenyu Guo , Fuhui Xiong , Wenshan Xu

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Deep Neural Networks (DNNs) are widely used for decision making in a myriad of critical applications, ranging from medical to societal and even judicial. Given the importance of these decisions, it is crucial for us to be able to interpret…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Teddy Koker , Fatemehsadat Mireshghallah , Tom Titcombe , Georgios Kaissis

The ability to automatically learn task specific feature representations has led to a huge success of deep learning methods. When large training data is scarce, such as in medical imaging problems, transfer learning has been very effective.…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hariharan Ravishankar , Prasad Sudhakar , Rahul Venkataramani , Sheshadri Thiruvenkadam , Pavan Annangi , Narayanan Babu , Vivek Vaidya

In medical imaging, image synthesis is the estimation process of one image (sequence, modality) from another image (sequence, modality). Since images with different modalities provide diverse biomarkers and capture various features,…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Firoozeh Shomal Zadeh , Sevda Molani , Maysam Orouskhani , Marziyeh Rezaei , Mehrzad Shafiei , Hossein Abbasi

We report a framework based on a generative adversarial network (GAN) that performs high-fidelity color image reconstruction using a single hologram of a sample that is illuminated simultaneously by light at three different wavelengths. The…

Image and Video Processing · Electrical Eng. & Systems 2019-07-17 Tairan Liu , Zhensong Wei , Yair Rivenson , Kevin de Haan , Yibo Zhang , Yichen Wu , Aydogan Ozcan

Histopathology has played an essential role in cancer diagnosis. With the rapid advances in convolutional neural networks (CNN). Various CNN-based automated pathological image segmentation approaches have been developed in computer-assisted…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Cam Nguyen , Zuhayr Asad , Yuankai Huo

Performance achievable by modern deep learning approaches are directly related to the amount of data used at training time. Unfortunately, the annotation process is notoriously tedious and expensive, especially for pixel-wise tasks like…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Pierluigi Zama Ramirez , Alessio Tonioni , Luigi Di Stefano

Generative adversarial networks (GANs) are unsupervised Deep Learning approach in the computer vision community which has gained significant attention from the last few years in identifying the internal structure of multimodal medical…

Image and Video Processing · Electrical Eng. & Systems 2020-05-22 Nripendra Kumar Singh , Khalid Raza

Recent advances in Generative Adversarial Networks (GANs) have led to the creation of realistic-looking digital images that pose a major challenge to their detection by humans or computers. GANs are used in a wide range of tasks, from…

Image and Video Processing · Electrical Eng. & Systems 2020-07-22 Michael Goebel , Lakshmanan Nataraj , Tejaswi Nanjundaswamy , Tajuddin Manhar Mohammed , Shivkumar Chandrasekaran , B. S. Manjunath