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X-ray photon-counting detectors (PCDs) are drawing an increasing attention in recent years due to their low noise and energy discrimination capabilities. The energy/spectral dimension associated with PCDs potentially brings great benefits…

Medical Physics · Physics 2020-07-08 Mengzhou Li , David S. Rundle , Ge Wang

We consider the problem of signal reconstruction for computed tomography (CT) under a nonlinear forward model that accounts for exponential signal attenuation, a polychromatic X-ray source, general measurement noise (e.g., Poisson shot…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Mengqi Lou , Kabir Aladin Verchand , Sara Fridovich-Keil , Ashwin Pananjady

Photon-counting computed tomography has demonstrated significant advancements in recent years; however, micro photon-counting CT (Micro-PCCT) systems are still limited by pixel-wise detector response nonuniformity, which degrades…

Medical Physics · Physics 2026-03-31 Enze Zhou , Wenjian Li , Wenting Xu , Yuwei Lu , Shangbin Chen , Shaoyang Wang , Gang Zheng , Tianwu Xie , Qian Liu

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

Cone beam computed tomography (CBCT) is an emerging medical imaging technique to visualize the internal anatomical structures of patients. During a CBCT scan, several projection images of different angles or views are collectively utilized…

Image and Video Processing · Electrical Eng. & Systems 2024-01-18 Heejun Shin , Taehee Kim , Jongho Lee , Se Young Chun , Seungryung Cho , Dongmyung Shin

Compared with conventional single-energy computed tomography (CT), dual-energy CT (DECT) provides better material differentiation but most DECT imaging systems require dual full-angle projection data at different X-ray spectra. Relaxing the…

We introduce a new CT image reconstruction algorithm that is less affected by various artifacts. The new reconstruction algorithm is a method of minimizing the difference between synchrotron X-ray tomography data and sinograms generated…

Medical Physics · Physics 2021-11-22 Byung Chun Kim , Hyunju Lee , Kyungtaek Jun

Recent development of photon-counting CT (PCCT) brings great opportunities for plaque characterization with much-improved spatial resolution and spectral imaging capability. While existing coronary plaque PCCT imaging results are based on…

Medical Physics · Physics 2023-12-05 Mengzhou Li , Mingye Wu , Jed Pack , Pengwei Wu , Bruno De Man , Adam Wang , Koen Nieman , Ge Wang

A new model-based image adjustment for the enhancement of multi-resolution image fusion or pansharpening is proposed. Such image adjustment is needed for most pansharpening methods using panchromatic band and/or intensity image (calculated…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Gintautas Palubinskas

The recent development of energy-resolving scintillation crystals opens the way to new types of applications and imaging systems. In the context of computerized tomography (CT), it enables to use the energy as a dimension of information…

Numerical Analysis · Mathematics 2022-07-13 Lorenz Kuger , Gael Rigaud

Single Photon Emission Computed Tomography (SPECT) is one of the nuclear medicine imaging modalities used for functional analysis of animal and human organs. Gamma rays emitted from the scanned body are filtered with collimators and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-15 Manu Francis , Muhammed Tarek , Mark Pickering , Murat Tahtali

Material decomposition for imaging multiple contrast agents in a single acquisition has been made possible by spectral CT: a modality which incorporates multiple photon energy spectral sensitivities into a single data collection. This work…

Medical Physics · Physics 2020-08-11 Matthew Tivnan , Steven Tilley , J. Webster Stayman

Multi-spectral CT (MSCT) is increasingly used in industrial non-destructive testing and medical diagnosis because of its outstanding performance like material distinguishability. The process of obtaining MSCT data can be modeled as…

Numerical Analysis · Mathematics 2023-06-28 Huiying Pan , Shusen Zhao , Weibin Zhang , Huitao Zhang , Xing Zhao

Investigation of cell structure is hardly imaginable without bright-field microscopy. Numerous modifications such as depth-wise scanning or videoenhancement make this method being state-of-the-art. This raises a question what maximal…

Image and Video Processing · Electrical Eng. & Systems 2020-10-29 Kirill Lonhus , Renata Rychtarikova , Ganna Platonova , Dalibor Stys

The most realistic information about the transparent sample such as a live cell can be obtained only using bright-field light microscopy. At high-intensity pulsing LED illumination, we captured a primary 12-bit-per-channel (bpc) response…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 Ganna Platonova , Dalibor Stys , Pavel Soucek , Kirill Lonhus , Jan Valenta , Renata Rychtarikova

Computed Tomography (CT) scans provide detailed and accurate information of internal structures in the body. They are constructed by sending x-rays through the body from different directions and combining this information into a…

Image and Video Processing · Electrical Eng. & Systems 2023-05-12 Firas Khader , Gustav Müller-Franzes , Tianyu Han , Sven Nebelung , Christiane Kuhl , Johannes Stegmaier , Daniel Truhn

Computational corrections of defocus and aberrations in optical coherence tomography (OCT) offers a promising approach to realize high-resolution imaging with deep imaging depth, but without additional high hardware costs. However, these…

Optics · Physics 2025-10-28 Shuichi Makita , Naoki Fukutake , Lida Zhu , Yoshiaki Yasuno

The generation of synthetic CT (sCT) images from cone-beam CT (CBCT) data using deep learning methodologies represents a significant advancement in radiation oncology. This systematic review, following PRISMA guidelines and using the PICO…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Alzahra Altalib , Scott McGregor , Chunhui Li , Alessandro Perelli

This paper presents how photonics associated with new arising detection technologies is able to provide fully integrated instrument for coherent beam combination applied to astrophysical interferometry. The feasibility and operation of…

Instrumentation and Methods for Astrophysics · Physics 2010-11-02 Pierre Kern , Etienne Le Coärer , Pierre Benech
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