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Due to the energy-dependent nature of the attenuation coefficient and the polychromaticity of the X-ray source, beam hardening effect occurs when X-ray photons penetrate through an object, causing a nonlinear projection data. When a linear…

Medical Physics · Physics 2018-12-07 Wei Zhao , Dengwang Li , Kai Niu , Wenjian Qin , Hao Peng , Tianye Niu

Photon-counting spectral computed tomography is now clinically available. These new detectors come with the promise of higher contrast-to-noise ratio and spatial resolution and improved low-dose imaging. However, one important design…

Medical Physics · Physics 2023-02-03 Dennis Hein , Konstantinos Liappis , Fredrik Grönberg , Alma Eguizabal , Mats Persson

Spectral computed tomography based on a photon-counting detector (PCD) attracts more and more attentions since it has the capability to provide more accurate identification and quantitative analysis for biomedical materials. The limited…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Xiaodong Guo , Longhui Li , Dingyue Chang , Peng He , Peng Feng , Hengyong Yu , Weiwen Wu

The purpose of this work is to provide a fast and accurate scatter artifacts correction algorithm for cone beam CT (CBCT) imaging. The method starts with an estimation of coarse scatter profiles for a set of CBCT data in either image domain…

Medical Physics · Physics 2016-04-27 Wei Zhao , Don Vernekohl , Jun Zhu , Luyao Wang , Lei Xing

Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…

Spectral computed tomography (CT) offers the possibility to reconstruct attenuation images at different energy levels, which can be then used for material decomposition. However, traditional methods reconstruct each energy bin individually…

Computed tomography (CT) has been developed as a non-destructive technique for observing minute internal images of samples. It has been difficult to obtain photo-realistic (clean or clear) CT images due to various unwanted artifacts…

Quantum Physics · Physics 2023-09-12 Kyungtaek Jun

Scatter can account for large errors in cone-beam CT (CBCT) due to its wide field of view, and its complicated nature makes its compensation difficult. Iterative polyenergetic reconstruction algorithms offer the potential to provide…

Medical Physics · Physics 2020-01-13 Jonathan H. Mason , Alessandro Perelli , William H. Nailon , Mike E. Davies

Cone beam computed tomography (CBCT) images can be used for dose calculation in adaptive radiation therapy (ART). The main challenges are the large artefacts and inaccurate Hounsfield unit (HU) values. Currently, deformed planning CT images…

Medical Physics · Physics 2019-09-04 Xiao Liang , Liyuan Chen , Dan Nguyen , Zhiguo Zhou , Xuejun Gu , Ming Yang , Jing Wang , Steve Jiang

Spectral computed tomography (CT) has attracted much attention in radiation dose reduction, metal artifacts removal, tissue quantification and material discrimination. The x-ray energy spectrum is divided into several bins, each…

Image and Video Processing · Electrical Eng. & Systems 2021-08-26 Weiwen Wu , Dianlin Hu , Chuang Niu , Lieza Vanden Broeke , Anthony P. H. Butler , Peng Cao , James Atlas , Alexander Chernoglazov , Varut Vardhanabhuti , Ge Wang

Computer-Assisted Interventions enable clinicians to perform precise, minimally invasive procedures, often relying on advanced imaging methods. Cone-beam computed tomography (CBCT) can be used to facilitate computer-assisted interventions,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-04 Maximilian E. Tschuchnig , Philipp Steininger , Michael Gadermayr

Hybrid spectral CT integrates energy integrating detectors (EID) and photon counting detectors (PCD) into a single system, combining the large field-of-view advantage of EID with the high energy and spatial resolution of PCD. This…

Medical Physics · Physics 2024-10-25 Huiying Pan , Jianing Sun , Xu Jiang , Xing Zhao

Quantum simulators, in which well controlled quantum systems are used to reproduce the dynamics of less understood ones, have the potential to explore physics that is inaccessible to modeling with classical computers. However, checking the…

Quantum Physics · Physics 2015-06-18 C. Senko , J. Smith , P. Richerme , A. Lee , W. C. Campbell , C. Monroe

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is therefore challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable to…

Medical Physics · Physics 2020-10-27 Wei Zhao , Tianling Lyu , Yang Chen , Lei Xing

The work seeks to develop an algorithm for image reconstruction by directly inverting the non-linear data model in spectral CT. Using the non-linear data model, we formulate the image-reconstruction problem as a non-convex optimization…

Medical Physics · Physics 2021-02-23 Buxin Chen , Zheng Zhang , Dan Xia , Emil Y. Sidky , Xiaochuan Pan

Photon-counting detector based computed tomography (PCCT) has greatly advanced in recent years. However, spectral inconsistency, referring to inter-pixel variations in detected counts per energy bin, can easily leads to ring or band…

Medical Physics · Physics 2026-01-29 Yuting Chen , Yuxiang Xing , Li Zhang , Zhi Deng , Hewei Gao

The advent of computed tomography significantly improves patient health regarding diagnosis, prognosis, and treatment planning and verification. However, tomographic imaging escalates concomitant radiation doses to patients, inducing…

Cone Beam CT (CBCT) plays a crucial role in Adaptive Radiation Therapy (ART) by accurately providing radiation treatment when organ anatomy changes occur. However, CBCT images suffer from scatter noise and artifacts, making relying solely…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Linjie Fu , Xia Li , Xiuding Cai , Dong Miao , Yu Yao , Yali Shen

Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…

Medical Physics · Physics 2017-07-06 Jonathan Mason , Alessandro Perelli , William Nailon , Mike Davies

We describe the results from a simulation and experimental study of density estimation and beam hardening correction for Bremsstrahlung source computed tomography scan of objects made of a single material. The correction is done using…

Medical Physics · Physics 2025-11-05 Nikhil Deshmukh
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