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Parkinson's disease (PD), the second most prevalent neurodegenerative disorder worldwide, frequently presents with early-stage speech impairments. Recent advancements in Artificial Intelligence (AI), particularly deep learning (DL), have…

Sound · Computer Science 2024-09-25 Lisanne van Gelderen , Cristian Tejedor-García

Parkinson's disease (PD) is a neurodegenerative disorder, manifesting with motor and non-motor symptoms. Depressive symptoms are prevalent in PD, affecting up to 45% of patients. They are often underdiagnosed due to overlapping motor…

Parkinson's Disease (PD) is one of the most common types of neurological diseases caused by progressive degeneration of dopamin- ergic neurons in the brain. Even though there is no fixed cure for this neurodegenerative disease, earlier…

Computer Vision and Pattern Recognition · Computer Science 2018-06-21 Sara Soltaninejad , Irene Cheng , Anup Basu

Behavioral and Psychological Symptoms of Dementia (BPSD) impact dementia care substantially, affecting both patients and caregivers. Effective management and early detection of BPSD are crucial to reduce the stress and burden on caregivers…

Signal Processing · Electrical Eng. & Systems 2024-10-25 Benny Wei-Yun Hsu , Yu-Ming Chen , Yuan-Han Yang , Vincent S. Tseng

The limited availability of dysarthric speech data makes cross-lingual detection an important but challenging problem. A key difficulty is that speech representations often encode language-dependent structure that can confound dysarthria…

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Parkinsons disease is the second most prevalent neurodegenerative disorder with over ten million active cases worldwide and one million new diagnoses per year. Detecting and subsequently diagnosing the disease is challenging because of…

Computation and Language · Computer Science 2024-04-09 Jonathan Crawford

This Signal Processing Grand Challenge (SPGC) targets a difficult automatic prediction problem of societal and medical relevance, namely, the detection of Alzheimer's Dementia (AD). Participants were invited to employ signal processing and…

Audio and Speech Processing · Electrical Eng. & Systems 2023-01-16 Saturnino Luz , Fasih Haider , Davida Fromm , Ioulietta Lazarou , Ioannis Kompatsiaris , Brian MacWhinney

Preoperative improvement rate prediction for Parkinson's disease surgery is clinically important yet difficult because imaging signals are subtle and patients are heterogeneous. We address this setting, where only information available…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yand Wang , Chen Zhang , Lanyun Zhu , Yixin Chen , Qunbo Wang , Yutong Bai , Jurgen Germann , Yinghong Wen , Shuai Shao

Background: Huntington's disease (HD) is a rare, genetically determined brain disorder that limits the life of the patient, although early prognosis of HD can substantially improve the patient's quality of life. Current HD prognosis methods…

Signal Processing · Electrical Eng. & Systems 2023-02-09 Sucheer Maddury

Freezing of gait (FoG) is a common gait disability in Parkinson's disease, that usually appears in its advanced stage. Freeze episodes are associated with falls, injuries, and psychological consequences, negatively affecting the patients'…

Signal Processing · Electrical Eng. & Systems 2019-09-10 Spyroula Masiala , Willem Huijbers , Martin Atzmueller

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

Machine Learning · Computer Science 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing

Evaluating neurological disorders such as Parkinson's disease (PD) is a challenging task that requires the assessment of several motor and non-motor functions. In this paper, we present an end-to-end deep learning framework to measure PD…

Computer Vision and Pattern Recognition · Computer Science 2020-12-25 Amirhossein Dadashzadeh , Alan Whone , Michal Rolinski , Majid Mirmehdi

Speech-language pathologists (SLPs) frequently use vocal exercises in the treatment of patients with speech disorders. Patients receive treatment in a clinical setting and need to practice outside of the clinical setting to generalize…

Computers and Society · Computer Science 2016-05-23 Harishchandra Dubey , J. Cody Goldberg , Kunal Mankodiya , Leslie Mahler

As one of the most prevalent neurodegenerative disorders, Parkinson's disease (PD) has a significant impact on the fine motor skills of patients. The complex interplay of different articulators during speech production and realization of…

Gait analysis is crucial for the diagnosis and monitoring of movement disorders like Parkinson's Disease. While computer vision models have shown potential for objectively evaluating parkinsonian gait, their effectiveness is limited by…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Vida Adeli , Soroush Mehraban , Majid Mirmehdi , Alan Whone , Benjamin Filtjens , Amirhossein Dadashzadeh , Alfonso Fasano , Andrea Iaboni , Babak Taati

LIFT-PD is an innovative self-supervised learning framework developed for real-time detection of Freezing of Gait (FoG) in Parkinson's Disease (PD) patients, using a single triaxial accelerometer. It minimizes the reliance on large labeled…

Signal Processing · Electrical Eng. & Systems 2024-10-29 Shovito Barua Soumma , Kartik Mangipudi , Daniel Peterson , Shyamal Mehta , Hassan Ghasemzadeh

Parkinson's Disease (PD) affects over 10 million people globally, with speech impairments often preceding motor symptoms by years, making speech a valuable modality for early, non-invasive detection. While recent deep-learning models…

Sound · Computer Science 2025-08-29 Terry Yi Zhong , Cristian Tejedor-Garcia , Martha Larson , Bastiaan R. Bloem

Several diseases of parkinsonian syndromes present similar symptoms at early stage and no objective widely used diagnostic methods have been approved until now. Positron emission tomography (PET) with $^{18}$F-FDG was shown to be able to…

Eye-tracking is an accessible and non-invasive technology that provides information about a subject's motor and cognitive abilities. As such, it has proven to be a valuable resource in the study of neurodegenerative diseases such as…

Machine Learning · Computer Science 2023-11-29 Gonzalo Uribarri , Simon Ekman von Huth , Josefine Waldthaler , Per Svenningsson , Erik Fransén