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This paper presents a microfluidic device that implements standing surface acoustic waves in order to handle single cells, droplets, and generally particles. The particles are moved in a very controlled manner by the two-dimensional…
We propose to drive open microfluidic systems by shear in a covering fluid layer, e.g., oil covering water-filled chemical channels. The advantages as compared to other means of pumping are simpler forcing and prevention of evaporation of…
The development of compact and bright XUV and soft X-ray sources based on high-order harmonic generation is boosting advances towards understanding the behavior of matter with extreme temporal and spatial resolutions. Here, we report…
The lack of a simple operable method for longitudinal dynamic self-assembly of particles in a microchannel is one of the main problems in applying this technology to a wide range of researches, such as biomedical engineering, material…
Biomedical and biochemical processes in paper-based microfluidic devices often deal with mixing of two analytes to perform important functions. Uniform mixing of analytes in paper matrix is a challenging proposition, often necessitating…
Acoustically driven mixing of small fluid volumes is reported. Using surface acoustic waves on a mixer chip, conversion of those into bulk waves, and employing wave guiding effects enables us to distribute a set of "virtual sources" for…
A novel method to pump fluid in lab on chip devices with velocities up to tens of micrometer per second is introduced. A focused laser beam locally heats up an electrolyte. A net charge tends to accumulate in the heat-absorbing area, due to…
Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips are based on the principle of continuous fluid flow…
Microfluidic valves play a key role within microfluidic systems by regulating fluid flow through distinct microchannels, enabling many advanced applications in medical diagnostics, lab-on-chips, and laboratory automation. While microfluidic…
Pumping fluids without an aid of an external power source are desirable in a number of applications ranging from a cooling of microelectronic circuits to Micro Total Analysis Systems (micro-TAS). Although, several microfluidic pumps exist,…
We report the implementation of a fully on-chip, lensless microscopy technique termed optofluidic ptychography. This imaging modality complements the miniaturization provided by microfluidics and allows the integration of ptychographic…
We demonstrate a hybrid laser microfabrication approach, which combines the technical merits of ultrafast laser-assisted chemical etching and carbon dioxide laser-induced in-situ melting, for centimeter-scale and bonding-free fabrication of…
Cell spheroids are in vitro multicellular model systems that mimic the crowded micro-environment of biological tissues. Their mechanical characterization can provide valuable insights in how single-cell mechanics and cell-cell interactions…
An ion-exchange-resin-based microfluidic pump is introduced that utilizes trace amounts of ions to generate fluid flows. We show experimentally that our pump operates in almost deionized water for periods exceeding 24h and induces fluid…
We have designed and fabricated a microfluidic-based platform for sensing mechanical forces generated by cardiac microtissues in a highly-controlled microenvironment. Our fabrication approach combines Direct Laser Writing (DLW) lithography…
Micropumps are one of the most important parts of a microfluidic system. In particular, for biomedical applications such as Lab-on-Chip systems, micropumps are used to transport and manipulate test fluids in a controlled manner. In this…
Two-dimensional metal particle focusing is an essential task for various fabrication processes. While acoustofluidic devices can manipulate particles in two dimensions, the production of these devices often demands a cleanroom environment.…
Molecular communication (MC) is a bio-inspired method of transmitting information using biochemical signals, promising for novel medical, agricultural, and environmental applications at the intersection of bio-, nano-, and communication…
We describe a technique for surface and sub-surface micro-machining of glass substrates using tightly focused femtosecond laser pulses at a wavelength of 1660 nm. Although silicate glass is normally transparent at this wavelength, the…
Previous devices to separate cells by the characteristic force they experience due to dielectrophoresis, which depends on the size and electric properties of the particle, were limited by the flow rates and particle concentrations…