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Due to its predominantly asymptomatic or mildly symptomatic progression, lung cancer is often diagnosed in advanced stages, resulting in poorer survival rates for patients. As with other cancers, early detection significantly improves the…

Though large-scale datasets are essential for training deep learning systems, it is expensive to scale up the collection of medical imaging datasets. Synthesizing the objects of interests, such as lung nodules, in medical images based on…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Jie Yang , Siqi Liu , Sasa Grbic , Arnaud Arindra Adiyoso Setio , Zhoubing Xu , Eli Gibson , Guillaume Chabin , Bogdan Georgescu , Andrew F. Laine , Dorin Comaniciu

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Lung cancer has a high rate of recurrence in early-stage patients. Predicting the post-surgical recurrence in lung cancer patients has traditionally been approached using single modality information of genomics or radiology images. We…

Image and Video Processing · Electrical Eng. & Systems 2020-02-07 Vaishnavi Subramanian , Minh N. Do , Tanveer Syeda-Mahmood

Recent studies have shown that lung cancer screening using annual low-dose computed tomography (CT) reduces lung cancer mortality by 20% compared to traditional chest radiography. Therefore, CT lung screening has started to be used widely…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Gorkem Polat , Yesim Dogrusoz Serinagaoglu , Ugur Halici

We develop and validate a novel spherical radiomics framework for predicting key molecular biomarkers using multiparametric MRI. Conventional Cartesian radiomics extract tumor features on orthogonal grids, which do not fully capture the…

Medical Physics · Physics 2025-10-22 Haotian Feng , Ke Sheng

Background: We aim to develop enriched radiomics features that integrate classical structural radiomics with novel functional radiomics derived from liver MRI for diagnosis and risk stratification in liver cancer. The proposed framework…

Traditional survival models such as the Cox proportional hazards model are typically based on scalar or categorical clinical features. With the advent of increasingly large image datasets, it has become feasible to incorporate quantitative…

Computer Vision and Pattern Recognition · Computer Science 2020-01-09 Christoph Haarburger , Philippe Weitz , Oliver Rippel , Dorit Merhof

The early detection and nuanced subtype classification of non-small cell lung cancer (NSCLC), a predominant cause of cancer mortality worldwide, is a critical and complex issue. In this paper, we introduce an innovative integration of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Salma Hassan , Hamad Al Hammadi , Ibrahim Mohammed , Muhammad Haris Khan

The inherent characteristics of lung tissues, which are independent of breathing manoeuvre, may provide fundamental information on lung function. This paper attempted to study function-correlated lung textures and their spatial distribution…

Medical Physics · Physics 2024-03-28 Yu-Hua Huang , Xinzhi Teng , Jiang Zhang , Zhi Chen , Zongrui Ma , Ge Ren , Feng-Ming , Kong , Jing Cai

Purpose: The lung nodules localization in CT scan images is the most difficult task due to the complexity of the arbitrariness of shape, size, and texture of lung nodules. This is a challenge to be faced when coming to developing different…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Haytham Al Ewaidat , Youness El Brag

With a high rate of morbidity and mortality, colorectal cancer (CRC) ranks third in mortality among cancers. By analyzing the texture properties of images and quantifying the heterogeneity of tumors, radiomics and radiogenomics are…

Medical Physics · Physics 2024-06-25 Parsa Karami , Reza Elahi

A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector computed-tomography (CT) images has been developed in the framework of the MAGIC-5 Italian project. One of the main goals of this…

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

In this work, we present a fully automated lung computed tomography (CT) cancer diagnosis system, DeepLung. DeepLung consists of two components, nodule detection (identifying the locations of candidate nodules) and classification…

Computer Vision and Pattern Recognition · Computer Science 2018-01-30 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie

Lung cancer is highly lethal, emphasizing the critical need for early detection. However, identifying lung nodules poses significant challenges for radiologists, who rely heavily on their expertise for accurate diagnosis. To address this…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Hossein Jafari , Karim Faez , Hamidreza Amindavar

Lung cancer remains one of the leading causes of morbidity and mortality worldwide, making early diagnosis critical for improving therapeutic outcomes and patient prognosis. Computer-aided diagnosis systems, which analyze computed…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Guohui Cai , Ying Cai , Zeyu Zhang , Yuanzhouhan Cao , Lin Wu , Daji Ergu , Zhinbin Liao , Yang Zhao

In this study, a morphological differentiation-based method has been introduced which employs temperature distribution on the tissue surface to detect brain tumor's malignancy. According to the common tumor CT scans, two different scenarios…

Computer Vision and Pattern Recognition · Computer Science 2023-02-22 Hamed Hani , Afsaneh Mojra

In the context of brain tumor characterization, we focused on two key questions: (a) stability of radiomics features to variability in multiregional segmentation masks obtained with fully-automatic deep segmentation methods and (b)…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Maria Nadeem , Asma Shaheen , Muhammad F. A. Chaudhary , Hassan Mohy-ud-Din

Accurate assessment of Lung nodules is a time consuming and error prone ingredient of the radiologist interpretation work. Automating 3D volume detection and segmentation can improve workflow as well as patient care. Previous works have…

Image and Video Processing · Electrical Eng. & Systems 2019-07-29 Evi Kopelowitz , Guy Engelhard
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