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Background: The high dimensionality of radiomic feature sets, the variability in radiomic feature types and potentially high computational requirements all underscore the need for an effective method to identify the smallest set of…

In this study, a radiomics approach was extended to optical fluorescence molecular imaging data for tissue classification, termed 'optomics'. Fluorescence molecular imaging is emerging for precise surgical guidance during head and neck…

Accurate and timely identification of pulmonary nodules on chest X-rays can differentiate between life-saving early treatment and avoidable invasive procedures. Calcification is a definitive indicator of benign nodules and is the primary…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Hyeonjin Choi , Yang-gon Kim , Dong-yeon Yoo , Ju-sung Sun , Jung-won Lee

Detecting malignant pulmonary nodules at an early stage can allow medical interventions which may increase the survival rate of lung cancer patients. Using computer vision techniques to detect nodules can improve the sensitivity and the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Siqi Liu , Arnaud Arindra Adiyoso Setio , Florin C. Ghesu , Eli Gibson , Sasa Grbic , Bogdan Georgescu , Dorin Comaniciu

Tumor shape is a key factor that affects tumor growth and metastasis. This paper proposes a topological feature computed by persistent homology to characterize tumor progression from digital pathology and radiology images and examines its…

Computer Vision and Pattern Recognition · Computer Science 2023-03-01 Chul Moon , Qiwei Li , Guanghua Xiao

The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…

Machine Learning · Computer Science 2023-06-16 Matteo Tortora , Ermanno Cordelli , Rosa Sicilia , Lorenzo Nibid , Edy Ippolito , Giuseppe Perrone , Sara Ramella , Paolo Soda

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Pulmonary nodules are an early sign of lung cancer, and detecting them early is vital for improving patient survival rates. Most current methods use only single Computed Tomography (CT) images to assess nodule malignancy. However, doctors…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Yin Shen , Zhaojie Fang , Ke Zhuang , Guanyu Zhou , Xiao Yu , Yucheng Zhao , Yuan Tian , Ruiquan Ge , Changmiao Wang , Xiaopeng Fan , Ahmed Elazab

As an analytic pipeline for quantitative imaging feature extraction and analysis, radiomics has grown rapidly in the past a few years. Recent studies in radiomics aim to investigate the relationship between tumors imaging features and…

Quantitative Methods · Quantitative Biology 2019-07-11 Yucheng Zhang , Edrise M. Lobo-Mueller , Paul Karanicolas , Steven Gallinger , Masoom A. Haider , Farzad Khalvati

Lung cancer is the commonest cause of cancer deaths worldwide, and its mortality can be reduced significantly by performing early diagnosis and screening. Since the 1960s, driven by the pressing needs to accurately and effectively interpret…

Computer Vision and Pattern Recognition · Computer Science 2020-04-27 Bo Liu , Wenhao Chi , Xinran Li , Peng Li , Wenhua Liang , Haiping Liu , Wei Wang , Jianxing He

We propose a deep learning based method for classification of commonly occurring pathologies in chest X-ray images. The vast number of publicly available chest X-ray images provides the data necessary for successfully employing deep…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Mohammad S. Majdi , Khalil N. Salman , Michael F. Morris , Nirav C. Merchant , Jeffrey J. Rodriguez

Early detection of lung nodules with computed tomography (CT) is critical for the longer survival of lung cancer patients and better quality of life. Computer-aided detection/diagnosis (CAD) is proven valuable as a second or concurrent…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Chuang Niu , Ge Wang

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Accurate detection of pulmonary nodules with high sensitivity and specificity is essential for automatic lung cancer diagnosis from CT scans. Although many deep learning-based algorithms make great progress for improving the accuracy of…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Jingya Liu , Liangliang Cao , Oguz Akin , Yingli Tian

2D and 3D tumor features are widely used in a variety of medical image analysis tasks. However, for chemotherapy response prediction, the effectiveness between different kinds of 2D and 3D features are not comprehensively assessed,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Neman Abdoli , Ke Zhang , Patrik Gilley , Xuxin Chen , Youkabed Sadri , Theresa C. Thai , Lauren E. Dockery , Kathleen Moore , Robert S. Mannel , Yuchen Qiu

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

To develop and externally validate integrated ultrasound nomograms combining BIRADS features and quantitative morphometric characteristics, and to compare their performance with expert radiologists and state of the art large language models…

Objective: In clinical practice, small lung nodules can be easily overlooked by radiologists. The paper aims to provide an efficient and accurate detection system for small lung nodules while keeping good performance for large nodules.…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Sunyi Zheng , Ludo J. Cornelissen , Xiaonan Cui , Xueping Jing , Raymond N. J. Veldhuis , Matthijs Oudkerk , Peter M. A. van Ooijen

Early detection of lung cancer is essential in reducing mortality. Recent studies have demonstrated the clinical utility of low-dose computed tomography (CT) to detect lung cancer among individuals selected based on very limited clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-02-25 Jiachen Wang , Riqiang Gao , Yuankai Huo , Shunxing Bao , Yunxi Xiong , Sanja L. Antic , Travis J. Osterman , Pierre P. Massion , Bennett A. Landman

Lung Cancer is the most common cause of cancer-related death worldwide. Early and automatic diagnosis of Solitary Pulmonary Nodules (SPN) in Computer Tomography (CT) chest scans can provide early treatment as well as doctor liberation from…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Ioannis D. Apostolopoulos