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Machine learning (ML) systems for medical imaging have demonstrated remarkable diagnostic capabilities, but their susceptibility to biases poses significant risks, since biases may negatively impact generalization performance. In this…

Machine Learning · Computer Science 2025-04-29 Haroui Ma , Francesco Quinzan , Theresa Willem , Stefan Bauer

Counterfactual image generation presents significant challenges, including preserving identity, maintaining perceptual quality, and ensuring faithfulness to an underlying causal model. While existing auto-encoding frameworks admit semantic…

Machine Learning · Computer Science 2025-06-10 Rajat Rasal , Avinash Kori , Fabio De Sousa Ribeiro , Tian Xia , Ben Glocker

Cephalometric landmark detection is essential for orthodontic diagnostics and treatment planning. Nevertheless, the scarcity of samples in data collection and the extensive effort required for manual annotation have significantly impeded…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Dongqian Guo , Wencheng Han , Pang Lyu , Yuxi Zhou , Jianbing Shen

We introduce the concept of deceptive diffusion -- training a generative AI model to produce adversarial images. Whereas a traditional adversarial attack algorithm aims to perturb an existing image to induce a misclassificaton, the…

Machine Learning · Computer Science 2024-07-01 Lucas Beerens , Catherine F. Higham , Desmond J. Higham

We investigate whether synthetic images generated by diffusion models can enhance multi-label classification of protein subcellular localization. Specifically, we implement a simplified class-conditional denoising diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Sylvey Lin , Zhi-Yi Cao

Preparing training data for deep vision models is a labor-intensive task. To address this, generative models have emerged as an effective solution for generating synthetic data. While current generative models produce image-level category…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Quang Nguyen , Truong Vu , Anh Tran , Khoi Nguyen

Weakly supervised medical image segmentation (MIS) using generative models is crucial for clinical diagnosis. However, the accuracy of the segmentation results is often limited by insufficient supervision and the complex nature of medical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Zhihao Shuai , Yinan Chen , Shunqiang Mao , Yihan Zho , Xiaohong Zhang

Counterfactual medical image generation have emerged as a critical tool for enhancing AI-driven systems in medical domain by answering "what-if" questions. However, existing approaches face two fundamental limitations: First, they fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hyungi Min , Taeseung You , Hangyeul Lee , Yeongjae Cho , Sungzoon Cho

We describe Countersynth, a conditional generative model of diffeomorphic deformations that induce label-driven, biologically plausible changes in volumetric brain images. The model is intended to synthesise counterfactual training data…

Computer Vision and Pattern Recognition · Computer Science 2021-12-01 Guilherme Pombo , Robert Gray , Jorge Cardoso , Sebastien Ourselin , Geraint Rees , John Ashburner , Parashkev Nachev

Scaling by training on large datasets has been shown to enhance the quality and fidelity of image generation and manipulation with diffusion models; however, such large datasets are not always accessible in medical imaging due to cost and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-14 Yousef Yeganeh , Azade Farshad , Ioannis Charisiadis , Marta Hasny , Martin Hartenberger , Björn Ommer , Nassir Navab , Ehsan Adeli

The Diffusion Probabilistic Model (DPM) has recently gained popularity in the field of computer vision, thanks to its image generation applications, such as Imagen, Latent Diffusion Models, and Stable Diffusion, which have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2023-12-27 Junde Wu , Wei Ji , Huazhu Fu , Min Xu , Yueming Jin , Yanwu Xu

Brain tumor analysis in Magnetic Resonance Imaging (MRI) is crucial for accurate diagnosis and treatment planning. However, the task remains challenging due to the complexity and variability of tumor appearances, as well as the scarcity of…

Image and Video Processing · Electrical Eng. & Systems 2024-07-18 Yiqing Shen , Guannan He , Mathias Unberath

Counterfactuals can explain classification decisions of neural networks in a human interpretable way. We propose a simple but effective method to generate such counterfactuals. More specifically, we perform a suitable diffeomorphic…

Machine Learning · Computer Science 2022-06-17 Ann-Kathrin Dombrowski , Jan E. Gerken , Klaus-Robert Müller , Pan Kessel

Skin lesion segmentation plays a critical role in the early detection and accurate diagnosis of dermatological conditions. Denoising Diffusion Probabilistic Models (DDPMs) have recently gained attention for their exceptional…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Afshin Bozorgpour , Yousef Sadegheih , Amirhossein Kazerouni , Reza Azad , Dorit Merhof

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Deep learning is dramatically transforming the field of medical imaging and radiology, enabling the identification of pathologies in medical images, including computed tomography (CT) and X-ray scans. However, the performance of deep…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Dmytro Shvetsov , Joonas Ariva , Marharyta Domnich , Raul Vicente , Dmytro Fishman

Over the past years, pseudo-healthy reconstruction for unsupervised anomaly detection has gained in popularity. This approach has the great advantage of not requiring tedious pixel-wise data annotation and offers possibility to generalize…

Image and Video Processing · Electrical Eng. & Systems 2024-01-30 Ravi Hassanaly , Camille Brianceau , Maëlys Solal , Olivier Colliot , Ninon Burgos

In this study, we introduce a generative model that can synthesize a large number of radiographical image/label pairs, and thus is asymptotically favorable to downstream activities such as segmentation in bio-medical image analysis.…

Image and Video Processing · Electrical Eng. & Systems 2023-04-20 Pham Ngoc Huy , Tran Minh Quan

Deep learning techniques for anatomical landmark localization (ALL) have shown great success, but their reliance on large annotated datasets remains a problem due to the tedious and costly nature of medical data acquisition and annotation.…

Computer Vision and Pattern Recognition · Computer Science 2024-10-18 Arnela Hadzic , Lea Bogensperger , Simon Johannes Joham , Martin Urschler

Image generation is a prevailing technique for clinical data augmentation for advancing diagnostic accuracy and reducing healthcare disparities. Diffusion Model (DM) has become a leading method in generating synthetic medical images, but it…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Ruichen Zhang , Yuguang Yao , Zhen Tan , Zhiming Li , Pan Wang , Huan Liu , Jingtong Hu , Sijia Liu , Tianlong Chen