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Deep learning (DL) models in medical imaging face challenges in generalizability and robustness due to variations in image acquisition parameters (IAP). In this work, we introduce a novel method using conditional denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Pedro Morão , Joao Santinha , Yasna Forghani , Nuno Loução , Pedro Gouveia , Mario A. T. Figueiredo

Deep learning models in medical imaging often fail when deployed in new clinical environments due to distribution shifts in demographics, scanner hardware, or acquisition protocols. A central challenge is underspecification, where models…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Moritz Stammel , Fabio De Sousa Ribeiro , Raghav Mehta , Mélanie Roschewitz , Ben Glocker

As acquiring MRIs is expensive, neuroscience studies struggle to attain a sufficient number of them for properly training deep learning models. This challenge could be reduced by MRI synthesis, for which Generative Adversarial Networks…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Wei Peng , Ehsan Adeli , Tomas Bosschieter , Sang Hyun Park , Qingyu Zhao , Kilian M. Pohl

Ascription of an image gives insights into the objects that influence the classification of the whole image or its pixels towards a specific category. These insights help radiologists to visualize deformities in medical imaging. Most of the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Shakeeb Murtaza

Mammogram benign or malignant classification with only image-level labels is challenging due to the absence of lesion annotations. Motivated by the symmetric prior that the lesions on one side of breasts rarely appear in the corresponding…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Chu-ran Wang , Jing Li , Fandong Zhang , Xinwei Sun , Hao Dong , Yizhou Yu , Yizhou Wang

Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Deep learning models for skin disease classification require large, diverse, and well-annotated datasets. However, such resources are often limited due to privacy concerns, high annotation costs, and insufficient demographic representation.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Jamil Fayyad , Nourhan Bayasi , Ziyang Yu , Homayoun Najjaran

The image-based diagnosis is now a vital aspect of modern automation assisted diagnosis. To enable models to produce pixel-level diagnosis, pixel-level ground-truth labels are essentially required. However, since it is often not straight…

Computer Vision and Pattern Recognition · Computer Science 2023-01-24 Tehseen Zia , Zeeshan Nisar , Shakeeb Murtaza

Developing reliable and generalizable deep learning systems for medical imaging faces significant obstacles due to spurious correlations, data imbalances, and limited text annotations in datasets. Addressing these challenges requires…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Amar Kumar , Anita Kriz , Mohammad Havaei , Tal Arbel

With the ongoing rise of machine learning, the need for methods for explaining decisions made by artificial intelligence systems is becoming a more and more important topic. Especially for image classification tasks, many state-of-the-art…

Machine Learning · Computer Science 2022-05-10 Silvan Mertes , Tobias Huber , Katharina Weitz , Alexander Heimerl , Elisabeth André

Estimating the counterfactual outcome of treatment is essential for decision-making in public health and clinical science, among others. Often, treatments are administered in a sequential, time-varying manner, leading to an exponentially…

Machine Learning · Statistics 2024-07-16 Shenghao Wu , Wenbin Zhou , Minshuo Chen , Shixiang Zhu

Accurate segmentation of punctate white matter lesions (PWMLs) are fundamental for the timely diagnosis and treatment of related developmental disorders. Automated PWMLs segmentation from infant brain MR images is challenging, considering…

Image and Video Processing · Electrical Eng. & Systems 2023-09-08 Zehua Ren , Yongheng Sun , Miaomiao Wang , Yuying Feng , Xianjun Li , Chao Jin , Jian Yang , Chunfeng Lian , Fan Wang

Pseudo-normality synthesis, which computationally generates a pseudo-normal image from an abnormal one (e.g., with lesions), is critical in many perspectives, from lesion detection, data augmentation to clinical surgery suggestion. However,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-30 Yuanqi Du , Quan Quan , Hu Han , S. Kevin Zhou

The success of Deep Learning applications critically depends on the quality and scale of the underlying training data. Generative adversarial networks (GANs) can generate arbitrary large datasets, but diversity and fidelity are limited,…

Recent advances in Diffusion Probabilistic Models (DPMs) have set new standards in high-quality image synthesis. Yet, controlled generation remains challenging, particularly in sensitive areas such as medical imaging. Medical images feature…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Sarah Cechnicka , Matthew Baugh , Weitong Zhang , Mischa Dombrowski , Zhe Li , Johannes C. Paetzold , Candice Roufosse , Bernhard Kainz

Anatomical Landmark Detection is the process of identifying key areas of an image for clinical measurements. Each landmark is a single ground truth point labelled by a clinician. A machine learning model predicts the locus of a landmark as…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Julian Wyatt , Irina Voiculescu

Based on the Denoising Diffusion Probabilistic Model (DDPM), medical image segmentation can be described as a conditional image generation task, which allows to compute pixel-wise uncertainty maps of the segmentation and allows an implicit…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Xutao Guo , Yanwu Yang , Chenfei Ye , Shang Lu , Yang Xiang , Ting Ma

Free-form inpainting is the task of adding new content to an image in the regions specified by an arbitrary binary mask. Most existing approaches train for a certain distribution of masks, which limits their generalization capabilities to…

Computer Vision and Pattern Recognition · Computer Science 2022-09-01 Andreas Lugmayr , Martin Danelljan , Andres Romero , Fisher Yu , Radu Timofte , Luc Van Gool

Foundation models trained on web-scraped datasets propagate societal biases to downstream tasks. While counterfactual generation enables bias analysis, existing methods introduce artifacts by modifying contextual elements like clothing and…

Computer Vision and Pattern Recognition · Computer Science 2024-12-13 Kirill Sirotkin , Marcos Escudero-Viñolo , Pablo Carballeira , Mayug Maniparambil , Catarina Barata , Noel E. O'Connor

Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng