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A cell's behavior is a consequence of the complex interactions between its numerous constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling pathways and regulatory mechanisms to coordinate multiple processes,…

Molecular Networks · Quantitative Biology 2007-09-12 Reka Albert

Obtaining the free energies of condensed phase chemical reactions remains computationally prohibitive for high-level quantum mechanical methods. We introduce a hierarchical machine learning framework that bridges this gap by distilling…

Chemical Physics · Physics 2026-03-19 Chenghan Li , Garnet Kin-Lic Chan

We revisit the proof of the limiting free energy of the continuous random energy model (CREM) using the Hamilton--Jacobi approach for mean-field disordered systems. To achieve this, we introduce an enriched model that interpolates between…

Probability · Mathematics 2025-08-26 Alexander Alban , Fu-Hsuan Ho , Justin Ko

The cognitive state of mind concerning a range of choices to be made can effectively be modelled in terms of an element of a high-dimensional Hilbert space. The dynamics of the state of mind resulting form information acquisition is…

Neurons and Cognition · Quantitative Biology 2026-03-17 Dorje C Brody

For a biological agent operating under environmental pressure, energy consumption and reaction times are of critical importance. Similarly, engineered systems are optimized for short time-to-solution and low energy-to-solution…

Neuromorphic computing approaches become increasingly important as we address future needs for efficiently processing massive amounts of data. The unique attributes of quantum materials can help address these needs by enabling new…

Systems with many interacting stochastic constituents are fully characterized by their free energy. Computing this quantity is therefore the objective of various approaches, notably perturbative expansions, which are applied in problems…

Statistical Mechanics · Physics 2026-04-08 Tobias Kühn

Living systems face both environmental complexity and limited access to free-energy resources. Survival under these conditions requires a control system that can activate, or deploy, available perception and action resources in a context…

Neurons and Cognition · Quantitative Biology 2023-03-06 Chris Fields , Filippo Fabrocini , Karl Friston , James F. Glazebrook , Hananel Hazan , Michael Levin , Antonino Marciano

The methods of quantum field theory are widely used in condensed matter physics. In particular, the concept of an effective action was proven useful when studying low temperature and long distance behavior of condensed matter systems. Often…

Strongly Correlated Electrons · Physics 2017-08-25 Alexander G. Abanov

It is now generally assumed that the heterogeneity of most networks in nature probably arises via preferential attachment of some sort. However, the origin of various other topological features, such as degree-degree correlations and…

Adaptation and Self-Organizing Systems · Physics 2010-03-05 Samuel Johnson , J. Marro , Joaquin J. Torres

Neuronal morphology is an essential element for brain activity and function. We take advantage of current availability of brain-wide neuron digital reconstructions of the Pyramidal cells from a mouse brain, and analyze several emergent…

Dynamical Systems · Mathematics 2018-10-09 Congping Lin , Yuanfei Huang , Tingwei Quan , Yiwei Zhang

The Hopfield neural networks and the holographic neural networks are models which were successfully simulated on conventional computers. Starting with these models, an analogous fundamental quantum information processing system is developed…

Quantum Physics · Physics 2007-05-23 Mitja Perus , Horst Bischof

Volumetric brain reconstructions provide an unprecedented opportunity to gain insights into the complex connectivity patterns of neurons in an increasing number of organisms. Here, we model and quantify the complexity of the resulting…

Neurons and Cognition · Quantitative Biology 2024-05-13 Anastasiya Salova , István A. Kovács

One of the fundamental questions in Quantum Field Theory regards the determination of a measure of the degrees of freedom of theories that is consistent with the Renormalization Group flow. The answer seems to be encoded in the C-theorems,…

High Energy Physics - Theory · Physics 2018-03-19 Daniela D'Ascanio

Multiple studies of neural avalanches across different data modalities led to the prominent hypothesis that the brain operates near a critical point. The observed exponents often indicate the mean-field directed-percolation universality…

Neurons and Cognition · Quantitative Biology 2022-11-14 Roxana Zeraati , Victor Buendía , Tatiana A. Engel , Anna Levina

In this work, a conceptual bio-inspired parallel and distributed learning framework for the emergence of general intelligence is proposed, where agents evolve through environmental rewards and learn throughout their lifetime without…

Neural and Evolutionary Computing · Computer Science 2020-09-23 Sidney Pontes-Filho , Stefano Nichele

In this work we propose a computational scheme inspired by the workings of human cognition. We embed some fundamental aspects of the human cognitive system into this scheme in order to obtain a minimization of computational resources and…

Physics and Society · Physics 2015-03-20 Daniel Borkmann , Andrea Guazzini , Emanuele Massaro , Stefan Rudolph

Structural and functional heterogeneity are hallmarks of cortical circuits, from broad degree distributions in the mouse connectome to diverse intrinsic neuronal timescales. Yet a mechanistic link between connectivity heterogeneity and…

Neurons and Cognition · Quantitative Biology 2026-03-05 Marco Zenari , Luca Taffarello , Luca Mazzucato , Amos Maritan , Samir Suweis

Based on laboratory based growth of plant-like structures from inorganic materials, we present new theory for the emergence of plant structure at a range of scales dictated by levels of ionization (charge density), which can be traced…

General Physics · Physics 2017-01-24 Philip Turner , Laurent Nottale

We propose Symmetry-Loss, a brain-inspired algorithmic principle that enforces invariance and equivariance through a differentiable constraint derived from environmental symmetries. The framework models learning as the iterative refinement…

Neurons and Cognition · Quantitative Biology 2025-12-17 Arif Dönmez
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