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Automatic segmentation methods are an important advancement in medical image analysis. Machine learning techniques, and deep neural networks in particular, are the state-of-the-art for most medical image segmentation tasks. Issues with…

Image and Video Processing · Electrical Eng. & Systems 2021-11-25 Michael Yeung , Evis Sala , Carola-Bibiane Schönlieb , Leonardo Rundo

Class imbalance and the difficulty imbalance are the two types of data imbalance that affect the performance of neural networks in medical segmentation tasks. In class imbalance the loss is dominated by the majority classes and in…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Seyed Mohsen Hosseini

The Dice similarity coefficient (DSC) is both a widely used metric and loss function for biomedical image segmentation due to its robustness to class imbalance. However, it is well known that the DSC loss is poorly calibrated, resulting in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Michael Yeung , Leonardo Rundo , Yang Nan , Evis Sala , Carola-Bibiane Schönlieb , Guang Yang

The segmentation of skin lesions is a crucial task in clinical decision support systems for the computer aided diagnosis of skin lesions. Although deep learning-based approaches have improved segmentation performance, these models are often…

Image and Video Processing · Electrical Eng. & Systems 2021-02-23 Kumar Abhishek , Ghassan Hamarneh

Deep-learning has proved in recent years to be a powerful tool for image analysis and is now widely used to segment both 2D and 3D medical images. Deep-learning segmentation frameworks rely not only on the choice of network architecture but…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Carole H Sudre , Wenqi Li , Tom Vercauteren , Sébastien Ourselin , M. Jorge Cardoso

In many medical imaging and classical computer vision tasks, the Dice score and Jaccard index are used to evaluate the segmentation performance. Despite the existence and great empirical success of metric-sensitive losses, i.e. relaxations…

Image and Video Processing · Electrical Eng. & Systems 2020-10-27 Tom Eelbode , Jeroen Bertels , Maxim Berman , Dirk Vandermeulen , Frederik Maes , Raf Bisschops , Matthew B. Blaschko

The accuracy of deep learning methods for two foundational tasks in medical image analysis -- detection and segmentation -- can suffer from class imbalance. We propose a `switching loss' function that adaptively shifts the emphasis between…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Deepak Anand , Gaurav Patel , Yaman Dang , Amit Sethi

We propose two novel loss functions, Multiplicative Loss and Confidence-Adaptive Multiplicative Loss, for semantic segmentation in medical and cellular images. Although Cross Entropy and Dice Loss are widely used, their additive combination…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yuto Yokoi , Kazuhiro Hotta

Deep learning-based methods achieved impressive results for the segmentation of medical images. With the development of 3D fully convolutional networks (FCNs), it has become feasible to produce improved results for multi-organ segmentation…

Computer Vision and Pattern Recognition · Computer Science 2018-01-19 Chen Shen , Holger R. Roth , Hirohisa Oda , Masahiro Oda , Yuichiro Hayashi , Kazunari Misawa , Kensaku Mori

Most segmentation losses are arguably variants of the Cross-Entropy (CE) or Dice losses. On the surface, these two categories of losses seem unrelated, and there is no clear consensus as to which category is a better choice, with varying…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Bingyuan Liu , Jose Dolz , Adrian Galdran , Riadh Kobbi , Ismail Ben Ayed

Within medical imaging segmentation, the Dice coefficient and Hausdorff-based metrics are standard measures of success for deep learning models. However, modern loss functions for medical image segmentation often only consider the Dice…

Image and Video Processing · Electrical Eng. & Systems 2024-01-26 Adrian Celaya , Beatrice Riviere , David Fuentes

Image segmentation is critically important in almost all medical image analysis for automatic interpretations and processing. However, it is often challenging to perform image segmentation due to data imbalance between intra- and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Zhhengyong Huang , Yao Sui

Simultaneous segmentation of multiple organs from different medical imaging modalities is a crucial task as it can be utilized for computer-aided diagnosis, computer-assisted surgery, and therapy planning. Thanks to the recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-16 Saeid Asgari Taghanaki , Yefeng Zheng , S. Kevin Zhou , Bogdan Georgescu , Puneet Sharma , Daguang Xu , Dorin Comaniciu , Ghassan Hamarneh

Albeit the Dice loss is one of the dominant loss functions in medical image segmentation, most research omits a closer look at its derivative, i.e. the real motor of the optimization when using gradient descent. In this paper, we highlight…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Sofie Tilborghs , Jeroen Bertels , David Robben , Dirk Vandermeulen , Frederik Maes

Recent studies have demonstrated the superior performance of introducing ``scan-wise" contrast labels into contrastive learning for multi-organ segmentation on multi-phase computed tomography (CT). However, such scan-wise labels are…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Ho Hin Lee , Yucheng Tang , Han Liu , Yubo Fan , Leon Y. Cai , Qi Yang , Xin Yu , Shunxing Bao , Yuankai Huo , Bennett A. Landman

This paper presents a new robust loss function, the T-Loss, for medical image segmentation. The proposed loss is based on the negative log-likelihood of the Student-t distribution and can effectively handle outliers in the data by…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Alvaro Gonzalez-Jimenez , Simone Lionetti , Philippe Gottfrois , Fabian Gröger , Marc Pouly , Alexander Navarini

Segmentation is a fundamental task in medical image analysis. The clinical interest is often to measure the volume of a structure. To evaluate and compare segmentation methods, the similarity between a segmentation and a predefined ground…

Image and Video Processing · Electrical Eng. & Systems 2020-10-09 Jeroen Bertels , David Robben , Dirk Vandermeulen , Paul Suetens

In the last years, deep learning has dramatically improved the performances in a variety of medical image analysis applications. Among different types of deep learning models, convolutional neural networks have been among the most…

Image and Video Processing · Electrical Eng. & Systems 2021-04-23 Minh H. Vu , Gabriella Norman , Tufve Nyholm , Tommy Löfstedt

Fully convolutional deep neural networks carry out excellent potential for fast and accurate image segmentation. One of the main challenges in training these networks is data imbalance, which is particularly problematic in medical imaging…

Computer Vision and Pattern Recognition · Computer Science 2017-06-20 Seyed Sadegh Mohseni Salehi , Deniz Erdogmus , Ali Gholipour

We propose a generalized focal loss function based on the Tversky index to address the issue of data imbalance in medical image segmentation. Compared to the commonly used Dice loss, our loss function achieves a better trade off between…

Computer Vision and Pattern Recognition · Computer Science 2018-10-19 Nabila Abraham , Naimul Mefraz Khan
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