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A novel method for tackling the problem of imbalanced data in medical image segmentation is proposed in this work. In balanced cross entropy (CE) loss, which is a type of weighted CE loss, the weight assigned to each class is the in-verse…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Seyed Mohsen Hosseini , Mahdieh Soleymani Baghshah

This paper presents a study on the soft-Dice loss, one of the most popular loss functions in medical image segmentation, for situations where noise is present in target labels. In particular, the set of optimal solutions are characterized…

Computer Vision and Pattern Recognition · Computer Science 2023-05-05 Marcus Nordström , Henrik Hult , Atsuto Maki , Fredrik Löfman

In this paper, we propose a Dual Focal Loss (DFL) function, as a replacement for the standard cross entropy (CE) function to achieve a better treatment of the unbalanced classes in a dataset. Our DFL method is an improvement on the recently…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 Md Sazzad Hossain , Andrew P Paplinski , John M Betts

The Dice score is widely used for binary segmentation due to its robustness to class imbalance. Soft generalisations of the Dice score allow it to be used as a loss function for training convolutional neural networks (CNN). Although CNNs…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Lucas Fidon , Wenqi Li , Luis C. Garcia-Peraza-Herrera , Jinendra Ekanayake , Neil Kitchen , Sebastien Ourselin , Tom Vercauteren

This paper studies the cosine as basis function for the approximation of univariate and continuous functions without memory. This work studies a supervised learning to obtain the approximation coefficients, instead of using the Discrete…

Signal Processing · Electrical Eng. & Systems 2024-05-28 Ana I. Pérez-Neira , Marc Martinez-Gost , Miguel Ángel Lagunas

The soft Dice loss (SDL) has taken a pivotal role in numerous automated segmentation pipelines in the medical imaging community. Over the last years, some reasons behind its superior functioning have been uncovered and further optimizations…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Zifu Wang , Teodora Popordanoska , Jeroen Bertels , Robin Lemmens , Matthew B. Blaschko

In this paper, we propose a novel two-component loss for biomedical image segmentation tasks called the Instance-wise and Center-of-Instance (ICI) loss, a loss function that addresses the instance imbalance problem commonly encountered when…

Image and Video Processing · Electrical Eng. & Systems 2023-04-14 Muhammad Febrian Rachmadi , Charissa Poon , Henrik Skibbe

Medical image segmentation is a critical process in the field of medical imaging, playing a pivotal role in diagnosis, treatment, and research. It involves partitioning of an image into multiple regions, representing distinct anatomical or…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Charulkumar Chodvadiya , Navyansh Mahla , Kinshuk Gaurav Singh , Kshitij Sharad Jadhav

Metric learning has become an attractive field for research on the latest years. Loss functions like contrastive loss, triplet loss or multi-class N-pair loss have made possible generating models capable of tackling complex scenarios with…

Machine Learning · Computer Science 2019-05-28 Alfonso Medela , Artzai Picon

Deep learning has proven to be a highly effective tool for a wide range of applications, significantly when leveraging the power of multi-loss functions to optimize performance on multiple criteria simultaneously. However, optimal selection…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Amin Golnari , Mostafa Diba

Nowadays, deep learning is the standard approach for a wide range of problems, including biometrics, such as face recognition and speech recognition, etc. Biometric problems often use deep learning models to extract features from images,…

Computer Vision and Pattern Recognition · Computer Science 2022-02-14 Pedro Silva , Gladston Moreira , Vander Freitas , Rodrigo Silva , David Menotti , Eduardo Luz

Target imbalance affects the performance of recent deep learning methods in many medical image segmentation tasks. It is a twofold problem: class imbalance - positive class (lesion) size compared to negative class (non-lesion) size; lesion…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Boris Shirokikh , Alexey Shevtsov , Anvar Kurmukov , Alexandra Dalechina , Egor Krivov , Valery Kostjuchenko , Andrey Golanov , Mikhail Belyaev

Accurate automated detection of recurrent prostate cancer in PSMA PET/CT scans is challenging due to heterogeneous lesion size, activity, anatomical location, and intra- and inter-class imbalances. Conventional deep learning loss functions…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 Obed Korshie Dzikunu , Shadab Ahamed , Amirhossein Toosi , Xiaoxiao Li , Arman Rahmim

Alignment remains a crucial task in multi-modal deep learning, and contrastive learning has been widely applied in this field. However, when there are more than two modalities, existing methods typically calculate pairwise loss function and…

Applications · Statistics 2025-05-07 Yiqiao Chen , Zijian Huang

Deep learning methods have contributed substantially to the rapid advancement of medical image segmentation, the quality of which relies on the suitable design of loss functions. Popular loss functions, including the cross-entropy and dice…

Image and Video Processing · Electrical Eng. & Systems 2022-11-07 Yucong Lin , Jinhua Su , Yuhang Li , Yuhao Wei , Hanchao Yan , Saining Zhang , Jiaan Luo , Danni Ai , Hong Song , Jingfan Fan , Tianyu Fu , Deqiang Xiao , Feifei Wang , Jue Hou , Jian Yang

Vascular segmentation in medical imaging plays a crucial role in analysing morphological and functional assessments. Traditional methods, like the centerline Dice (clDice) loss, ensure topology preservation but falter in capturing geometric…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Pengcheng Shi , Jiesi Hu , Yanwu Yang , Zilve Gao , Wei Liu , Ting Ma

The Dice score and Jaccard index are commonly used metrics for the evaluation of segmentation tasks in medical imaging. Convolutional neural networks trained for image segmentation tasks are usually optimized for (weighted) cross-entropy.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-09 Jeroen Bertels , Tom Eelbode , Maxim Berman , Dirk Vandermeulen , Frederik Maes , Raf Bisschops , Matthew Blaschko

Traditional loss functions in medical image segmentation, such as Dice, often under-segment small lesions because their small relative volume contributes negligibly to the overall loss. To address this, instance-wise loss functions and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Luc Bouteille , Alexander Jaus , Jens Kleesiek , Rainer Stiefelhagen , Lukas Heine

Deep-learning architectures for classification problems involve the cross-entropy loss sometimes assisted with auxiliary loss functions like center loss, contrastive loss and triplet loss. These auxiliary loss functions facilitate better…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Hongjun Choi , Anirudh Som , Pavan Turaga

We propose a simple modification from a fixed margin triplet loss to an adaptive margin triplet loss. While the original triplet loss is used widely in classification problems such as face recognition, face re-identification and…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Mai Lan Ha , Volker Blanz