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The problem of structure estimation in graphical models with latent variables is considered. We characterize conditions for tractable graph estimation and develop efficient methods with provable guarantees. We consider models where the…

Machine Learning · Statistics 2013-04-23 Animashree Anandkumar , Ragupathyraj Valluvan

Graph auto-encoders have proved to be useful in network embedding task. However, current models only consider explicit structures and fail to explore the informative latent structures cohered in networks. To address this issue, we propose a…

Machine Learning · Computer Science 2021-10-01 Minglong Lei , Yong Shi , Lingfeng Niu

Variational autoencoders (VAEs) and generative adversarial networks (GANs) enjoy an intuitive connection to manifold learning: in training the decoder/generator is optimized to approximate a homeomorphism between the data distribution and…

Machine Learning · Computer Science 2020-08-28 Henry Li , Ofir Lindenbaum , Xiuyuan Cheng , Alexander Cloninger

We consider the problem of modelling high-dimensional distributions and generating new examples of data with complex relational feature structure coherent with a graph skeleton. The model we propose tackles the problem of generating the…

Machine Learning · Computer Science 2022-12-02 Yoann Boget , Magda Gregorova , Alexandros Kalousis

Estimating causal effects from observational data (at either an individual -- or a population -- level) is critical for making many types of decisions. One approach to address this task is to learn decomposed representations of the…

Machine Learning · Computer Science 2021-11-15 Negar Hassanpour , Russell Greiner

Deep generative models are increasingly becoming integral parts of the in silico molecule design pipeline and have dual goals of learning the chemical and structural features that render candidate molecules viable while also being flexible…

Biomolecules · Quantitative Biology 2021-06-08 Yair Schiff , Vijil Chenthamarakshan , Karthikeyan Natesan Ramamurthy , Payel Das

Graphs are a fundamental abstraction for modeling relational data. However, graphs are discrete and combinatorial in nature, and learning representations suitable for machine learning tasks poses statistical and computational challenges. In…

Machine Learning · Statistics 2019-05-16 Aditya Grover , Aaron Zweig , Stefano Ermon

In this paper, we propose the first framework that enables solving graph learning tasks of all levels (node, edge and graph) and all types (generation, regression and classification) using one formulation. We first formulate prediction…

Machine Learning · Computer Science 2024-11-01 Cai Zhou , Xiyuan Wang , Muhan Zhang

The problem of molecular generation has received significant attention recently. Existing methods are typically based on deep neural networks and require training on large datasets with tens of thousands of samples. In practice, however,…

Machine Learning · Computer Science 2022-03-16 Minghao Guo , Veronika Thost , Beichen Li , Payel Das , Jie Chen , Wojciech Matusik

In data-driven drug discovery, designing molecular descriptors is a very important task. Deep generative models such as variational autoencoders (VAEs) offer a potential solution by designing descriptors as probabilistic latent vectors…

Machine Learning · Computer Science 2023-08-23 Daiki Koge , Naoaki Ono , Shigehiko Kanaya

In this work we explore deep generative models of text in which the latent representation of a document is itself drawn from a discrete language model distribution. We formulate a variational auto-encoder for inference in this model and…

Computation and Language · Computer Science 2016-10-17 Yishu Miao , Phil Blunsom

Graphical Markov models combine conditional independence constraints with graphical representations of stepwise data generating processes.The models started to be formulated about 40 years ago and vigorous development is ongoing.…

Methodology · Statistics 2015-10-12 Nanny Wermuth

Understanding the molecular processes that drive cellular life is a fundamental question in biological research. Ambitious programs have gathered a number of molecular datasets on large populations. To decipher the complex cellular…

Genomics · Quantitative Biology 2023-03-22 Myriam Bontonou , Anaïs Haget , Maria Boulougouri , Jean-Michel Arbona , Benjamin Audit , Pierre Borgnat

Inferring objects and their relationships from an image in the form of a scene graph is useful in many applications at the intersection of vision and language. We consider a challenging problem of compositional generalization that emerges…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Boris Knyazev , Harm de Vries , Cătălina Cangea , Graham W. Taylor , Aaron Courville , Eugene Belilovsky

We introduce deep neural networks for the analysis of anatomical shapes that learn a low-dimensional shape representation from the given task, instead of relying on hand-engineered representations. Our framework is modular and consists of…

Computer Vision and Pattern Recognition · Computer Science 2020-10-05 Benjamin Gutierrez Becker , Ignacio Sarasua , Christian Wachinger

Variational Autoencoders are powerful models for unsupervised learning. However deep models with several layers of dependent stochastic variables are difficult to train which limits the improvements obtained using these highly expressive…

Machine Learning · Statistics 2016-05-30 Casper Kaae Sønderby , Tapani Raiko , Lars Maaløe , Søren Kaae Sønderby , Ole Winther

Generative models for graph data are an important research topic in machine learning. Graph data comprise two levels that are typically analyzed separately: node-level properties such as the existence of a link between a pair of nodes, and…

Machine Learning · Computer Science 2023-01-18 Kiarash Zahirnia , Oliver Schulte , Parmis Naddaf , Ke Li

Various Graph Neural Networks (GNNs) have been successful in analyzing data in non-Euclidean spaces, however, they have limitations such as oversmoothing, i.e., information becomes excessively averaged as the number of hidden layers…

Machine Learning · Computer Science 2024-01-23 Jaeyoon Sim , Sooyeon Jeon , InJun Choi , Guorong Wu , Won Hwa Kim

Latent representations are the essence of deep generative models and determine their usefulness and power. For latent representations to be useful as generative concept representations, their latent space must support latent space…

Machine Learning · Computer Science 2019-01-01 Daniel T. Chang

Accurate and efficient prediction of the molecular properties of drugs is one of the fundamental problems in drug research and development. Recent advancements in representation learning have been shown to greatly improve the performance of…

Biomolecules · Quantitative Biology 2022-06-17 Hui Liu , Yibiao Huang , Xuejun Liu , Lei Deng
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