Related papers: A theoretic model for sonogenetic antiarrhythmia
Arrhythmia of the heart is a dangerous and potentially fatal condition. The current widely used treatment is the implantable cardioverter defibrillator (ICD), but it is invasive and affects the patient's quality of life. The sonogenetic…
Interruptions in nonlinear wave propagation, commonly referred to as wave breaks, are typical of many complex excitable systems. In the heart they lead to fatal rhythm disorders, the so-called arrhythmias, which are one of the main causes…
Hypertension is a medical condition that is well-established as a risk factor for many major diseases. For example, it can cause alterations in the cardiac structure and function over time that can lead to heart related morbidity and…
Computational models in cardiac electrophysiology are notorious for long runtimes, restricting the numbers of nodes and mesh elements in the numerical discretisations used for their solution. This makes it particularly challenging to…
Amplitude equations are derived that describe the spatiotemporal dynamics of cardiac alternans during periodic pacing of one- and two-dimensional homogeneous tissue and one-dimensional anatomical reentry in a ring of homogeneous tissue.…
In the present paper, a new three-scale asymptotic homogenization method is proposed to study the electrical behavior of the cardiac tissue structure with multiple heterogeneities at two different levels. The first level is associated with…
The resonance frequency of ultra-thin layered two-dimensional (2D) materials changes nonlinearly with the tension induced by the pressure from the surrounding gas. Although the dynamics of pressurized 2D material membranes have been…
Auxetics refers to structures or materials with a negative Poisson's ratio, thereby capable of exhibiting counter-intuitive behaviors. Herein, auxetic structures are exploited to design mechanically tunable metamaterials in both planar and…
Hypertension is a highly prevalent condition and a major risk factor for cardiovascular disease. The landmark Systolic Blood Pressure Intervention Trial (SPRINT) showed that lowering systolic blood pressure (BP) goals from 140 mmHg to 120…
In this paper, attention is drawn to the importance of accounting for osmotic pressure when analyzing physiological effects on cellular structures in plasma medicine. Interaction of a weakly ionized plasma jet with a saline solution leads…
We give an explicit formula for the membrane potential of cells in terms of the intracellular and extracellular ionic concentrations, and derive equations for the ionic currents that flow through channels, exchangers and electrogenic pumps…
Photoacoustic imaging systems offer a platform with high resolution to explore body tissues, food, and artwork. On the other hand, plasmonics constitutes a source of resonant heating and thermal expansion to generate acoustic waves.…
Synchronization of activity among myocytes constituting vital organs, e.g., the heart, is crucial for physiological functions. Self-organized coordination in such heterogeneous ensemble of excitable and oscillatory cells is therefore of…
A kinetic theory for radiation interacting with sound waves in an ultrarelativistic electron-positron plasma is developed. It is shown that the effect of a spatial spectral broadening of the electromagnetic pulse is to introduce a reduction…
Endocytosis is an essential process by which cells internalize a piece of plasma membrane and material from the outside. In cells with turgor, pressure opposes membrane defor- mations, and increases the amount of force that has to be…
Cardiac arrhythmogenesis is governed by complex electromechanical interactions that are not directly observable in vivo, motivating the development of non-invasive computational approaches for reconstructing three-dimensional activation…
Alterations of charges density on membranes (potentials) of plant cells by ion currents lead to disbalance of Coulomb forces compressing membranes and counteracting Hookean elastic forces. It should results in membrane vibrations till…
The propagation of acoustic and elastic waves in time-varying, spatially homogeneous media can exhibit different phenomena when compared to traditional spatially-varying, temporally-homogeneous media. In the present work, the response of a…
In this paper, we analyze the effect of the redistribution of the transmembrane ion channels in the axon caused by longitudinal acoustic vibrations of the membrane. These oscillations can be excited by an external source of ultrasound and…
Transmembrane ion flow through channel proteins undergoing density fluctuations may cause lateral gradients of the electrical potential across the membrane giving rise to electrophoresis of charged channels. A model for the dynamics of the…