Related papers: A theoretic model for sonogenetic antiarrhythmia
As an effective method to deliver external materials into biological cells, microinjection has been widely applied in the biomedical field. However, the cognition of cell mechanical property is still inadequate, which greatly limits the…
The work analytically substantiates the parameters of the surface wave found in numerical modelling of the collision of two oncoming supersonic plasma flows inside a magnetic arc in application to the experiment on the laboratory setup…
The ability of the Lorentz force to link a mechanical displacement to an electrical current presents a strong interest for medical acoustics, and three applications were studied in this thesis. In the first part of this work, a hydrophone…
This paper presents a new method for modeling the mechanics of the aortic valve, and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that the model is consistent with…
A severe application of stress on articular cartilage can initiate a cascade of biochemical reactions that can lead to the development of osteoarthritis. We constructed a multiscale mathematical model of the process with three components:…
Organogenesis is a tightly regulated process that has been studied experimentally for decades. We are developing mechanistic models for the morphogenesis of limbs, lungs, and kidneys with a view to integrate available knowledge and to…
Morphogenesis involves complex shape changes of biological tissues. Yet, tissue shape changes depend on tissue rheology, which in turn arises from the interplay of large numbers of cells. Here, we link cell- and tissue-scale mechanics by…
In this work, a sensitivity of the rate of relaxation of ground-state atomic coherences to magnetic-field inhomogeneities is studied. Such coherences give rise to many interesting phenomena in light-atom interactions, and their lifetimes…
Actuating the acoustic resonance modes of a microfluidic device containing suspended particles (e.g., cells) allows for the manipulation of their individual positions. In this work, we investigate how the number of resonance modes $M$…
We propose an experiment to extract ponderomotive squeezing from an interferometer with high circulating power and low mass mirrors. In this interferometer, optical resonances of the arm cavities are detuned from the laser frequency,…
Purpose: In treatment planning of charged-particle radiotherapy, patient heterogeneity is conventionally modeled as variable-density water converted from CT images to best reproduce the stopping power, which may lead to inaccuracies in the…
The latest experimental advances have extended the scenario of coupling mechanical degrees of freedom in chiral magnets (MnSi/MnGe) to the topologically nontrivial skyrmion crystal and even monopole lattices. Equipped with a spin-wave…
The radiation force on a single electron in an ultraintense plane wave ($a = eE/mc\omega \sim 1$) is calculated and shown to be proportional to $a^4$ in the high-$a$ limit for arbitrary waveform and polarization. The cyclotron motion of an…
We propose a coarse-grained theoretical model to capture the aging of microfluidic devices under different conditions including constant applied flow rate and constant applied pressure gradient. Microfluidic devices that sort cells by their…
Recently, it was shown that strongly driven micromechanical resonators show mode shapes that strongly differ from the eigenmodes. This raises the question of the origin of this nonlinear behavior. We measure the spatial dependence of the…
Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their…
Based on a non-equilibrium mechanism for spatial pattern formation we study how position information can be controlled by locally coupled discrete dynamical networks, similar to gene regulation networks of cells in a developing…
Improving resolution and sensitivity will widen possible medical applications of magnetic particle imaging. Pulsed excitation promises such benefits, at the cost of more complex hardware solutions and restrictions on drive field amplitude…
The aim of this paper is to provide a mathematical model for spatial distribution of membrane electrical potential changes by fluorescence diffuse optical tomography. We derive the resolving power of the imaging method in the presence of…
The actin cytoskeleton of cells is in continuous motion due to both polymerization of new filaments and their contraction by myosin II molecular motors. Through adhesion to the substrate, such intracellular flow can be converted into cell…