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Data-driven methods have shown tremendous progress in medical image analysis. In this context, deep learning-based supervised methods are widely popular. However, they require a large amount of training data and face issues in…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Ziang Xu , Jens Rittscher , Sharib Ali

Learning representations for individual instances when only bag-level labels are available is a fundamental challenge in multiple instance learning (MIL). Recent works have shown promising results using contrastive self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2023-07-13 Kangning Liu , Weicheng Zhu , Yiqiu Shen , Sheng Liu , Narges Razavian , Krzysztof J. Geras , Carlos Fernandez-Granda

Estimating disease severity from endoscopic images is essential in assessing ulcerative colitis, where the Mayo Endoscopic Subscore (MES) is widely used to grade inflammation. However, MES classification remains challenging due to label…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Zeynep Ozdemir , Hacer Yalim Keles , Omer Ozgur Tanriover

Multiple Instance Learning is the predominant method for Whole Slide Image classification in digital pathology, enabling the use of slide-level labels to supervise model training. Although MIL eliminates the tedious fine-grained annotation…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Chen Shu , Boyu Fu , Yiman Li , Ting Yin , Wenchuan Zhang , Jie Chen , Yuhao Yi , Hong Bu

Multiple Instance Learning (MIL) has emerged as the best solution for Whole Slide Image (WSI) classification. It consists of dividing each slide into patches, which are treated as a bag of instances labeled with a global label. MIL includes…

Computer Vision and Pattern Recognition · Computer Science 2025-05-05 Ali Mammadov , Loic Le Folgoc , Julien Adam , Anne Buronfosse , Gilles Hayem , Guillaume Hocquet , Pietro Gori

Ulcerative Colitis (UC) is an incurable inflammatory bowel disease that leads to ulcers along the large intestine and rectum. The increase in the prevalence of UC coupled with gastrointestinal physician shortages stresses the healthcare…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Venkat Margapuri

Ulcerative colitis (UC) classification, which is an important task for endoscopic diagnosis, involves two main difficulties. First, endoscopic images with the annotation about UC (positive or negative) are usually limited. Second, they show…

Image and Video Processing · Electrical Eng. & Systems 2023-03-03 Shota Harada , Ryoma Bise , Hideaki Hayashi , Kiyohito Tanaka , Seiichi Uchida

Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervision is typically provided only at the bag level, hindering the integrated consideration of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A. Fallowfield , Hideki Ueno , Hitoshi Tsuda , David J. Harrison , Hakan Bilen , Timothy J. Kendall

Automated disease diagnosis using medical image analysis relies on deep learning, often requiring large labeled datasets for supervised model training. Diseases like Acute Myeloid Leukemia (AML) pose challenges due to scarce and costly…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Salome Kazeminia , Max Joosten , Dragan Bosnacki , Carsten Marr

This work aims at improving instance retrieval with self-supervision. We find that fine-tuning using the recently developed self-supervised (SSL) learning methods, such as SimCLR and MoCo, fails to improve the performance of instance…

Computer Vision and Pattern Recognition · Computer Science 2021-12-03 Zelu Deng , Yujie Zhong , Sheng Guo , Weilin Huang

Class-incremental learning (CIL) for endoscopic image analysis is crucial for real-world clinical applications, where diagnostic models should continuously adapt to evolving clinical data while retaining performance on previously learned…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Bingrong Liu , Jun Shi , Yushan Zheng

Major Depressive Disorder (MDD) is a severe illness that affects millions of people, and it is critical to diagnose this disorder as early as possible. Detecting depression from voice signals can be of great help to physicians and can be…

Audio and Speech Processing · Electrical Eng. & Systems 2022-06-28 Jinhan Wang , Vijay Ravi , Jonathan Flint , Abeer Alwan

Patient-level diagnosis of severity in ulcerative colitis (UC) is common in real clinical settings, where the most severe score in a patient is recorded. However, previous UC classification methods (i.e., image-level estimation) mainly…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Kaito Shiku , Kazuya Nishimura , Daiki Suehiro , Kiyohito Tanaka , Ryoma Bise

Pretext Invariant Representation Learning (PIRL) followed by Supervised Fine-Tuning (SFT) has become a standard paradigm for learning with limited labels. We extend this approach to the Positive Unlabeled (PU) setting, where only a small…

Machine Learning · Computer Science 2025-04-11 Anish Acharya , Li Jing , Bhargav Bhushanam , Dhruv Choudhary , Michael Rabbat , Sujay Sanghavi , Inderjit S Dhillon

Lesion appearance is a crucial clue for medical providers to distinguish referable diabetic retinopathy (rDR) from non-referable DR. Most existing large-scale DR datasets contain only image-level labels rather than pixel-based annotations.…

Image and Video Processing · Electrical Eng. & Systems 2022-10-13 Wenhui Zhu , Peijie Qiu , Natasha Lepore , Oana M. Dumitrascu , Yalin Wang

Deep learning models have achieved state-of-the-art performance in many computer vision tasks. However, in real-world scenarios, novel classes that were unseen during training often emerge, requiring models to acquire new knowledge…

Computer Vision and Pattern Recognition · Computer Science 2025-09-01 Lucas Rakotoarivony

Intelligent fault diagnosis has made extraordinary advancements currently. Nonetheless, few works tackle class-incremental learning for fault diagnosis under limited fault data, i.e., imbalanced and long-tailed fault diagnosis, which brings…

Machine Learning · Computer Science 2023-02-14 Peng Peng , Hanrong Zhang , Mengxuan Li , Gongzhuang Peng , Hongwei Wang , Weiming Shen

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

Ulcerative Colitis (UC) is a chronic inflammatory bowel disease decreasing life quality through symptoms such as bloody diarrhoea and abdominal pain. Endoscopy is a cornerstone of diagnosis and monitoring of UC. The Mayo endoscopic subscore…

Image and Video Processing · Electrical Eng. & Systems 2024-04-16 Bjørn Leth Møller , Bobby Zhao Sheng Lo , Johan Burisch , Flemming Bendtsen , Ida Vind , Bulat Ibragimov , Christian Igel

High-quality annotation of fine-grained visual categories demands great expert knowledge, which is taxing and time consuming. Alternatively, learning fine-grained visual representation from enormous unlabeled images (e.g., species, brands)…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Qi Bi , Wei Ji , Jingjun Yi , Haolan Zhan , Gui-Song Xia
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