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Breast cancer is the most common invasive cancer in women, and the second main cause of death. Breast cancer screening is an efficient method to detect indeterminate breast lesions early. The common approaches of screening for women are…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Yuliana Jiménez Gaona , María José Rodriguez-Alvarez , Hector Espinó Morató , Darwin Castillo Malla , Vasudevan Lakshminarayanan

Biopsies are the gold standard for breast cancer diagnosis. This task can be improved by the use of Computer Aided Diagnosis (CAD) systems, reducing the time of diagnosis and reducing the inter and intra-observer variability. The advances…

Computer Vision and Pattern Recognition · Computer Science 2019-05-30 Jonathan de Matos , Alceu de S. Britto , Luiz E. S. de Oliveira , Alessandro L. Koerich

Deep learning models designed for visual classification tasks on natural images have become prevalent in medical image analysis. However, medical images differ from typical natural images in many ways, such as significantly higher…

Machine Learning · Computer Science 2019-08-21 Yiqiu Shen , Nan Wu , Jason Phang , Jungkyu Park , Gene Kim , Linda Moy , Kyunghyun Cho , Krzysztof J. Geras

Diagnosis of breast carcinomas has so far been limited to the morphological interpretation of epithelial cells and the assessment of epithelial tissue architecture. Consequently, most of the automated systems have focused on characterizing…

Computer Vision and Pattern Recognition · Computer Science 2017-02-21 Babak Ehteshami Bejnordi , Jimmy Linz , Ben Glass , Maeve Mullooly , Gretchen L Gierach , Mark E Sherman , Nico Karssemeijer , Jeroen van der Laak , Andrew H Beck

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…

Machine Learning · Computer Science 2021-11-11 Sheetal Rajpal , Virendra Kumar , Manoj Agarwal , Naveen Kumar

Breast cancer is a relatively common cancer among gynecological cancers. Its diagnosis often relies on the pathology of cells in the lesion. The pathological diagnosis of breast cancer not only requires professionals and time, but also…

Image and Video Processing · Electrical Eng. & Systems 2024-04-15 MingXuan Xiao , Yufeng Li , Xu Yan , Min Gao , Weimin Wang

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi

Some recent studies have described deep convolutional neural networks to diagnose breast cancer in mammograms with similar or even superior performance to that of human experts. One of the best techniques does two transfer learnings: the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-04 Daniel G. P. Petrini , Carlos Shimizu , Rosimeire A. Roela , Gabriel V. Valente , Maria A. A. K. Folgueira , Hae Yong Kim

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Accurate prediction of the likelihood of recurrence is important in the selection of postoperative treatment for patients with early-stage breast cancer. In this study, we investigated whether deep learning algorithms can predict patients'…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Geongyu Lee , Joonho Lee , Tae-Yeong Kwak , Sun Woo Kim , Youngmee Kwon , Chungyeul Kim , Hyeyoon Chang

Endometrial cancer, the fourth most common cancer in females in the United States, with the lifetime risk for developing this disease is approximately 2.8% in women. Precise histologic evaluation and molecular classification of endometrial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Manu Goyal , Laura J. Tafe , James X. Feng , Kristen E. Muller , Liesbeth Hondelink , Jessica L. Bentz , Saeed Hassanpour

This study introduces a novel and accurate approach to breast cancer classification using histopathology images. It systematically compares leading Convolutional Neural Network (CNN) models across varying image datasets, identifies their…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Gary Murphy , Raghubir Singh

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

For diagnosing melanoma, hematoxylin and eosin (H&E) stained tissue slides remains the gold standard. These images contain quantitative information in different magnifications. In the present study, we investigated whether deep…

Tissues and Organs · Quantitative Biology 2019-04-15 Peizhen Xie , Ke Zuo , Yu Zhang , Fangfang Li , Mingzhu Yin , Kai Lu

Breast cancer is a highly heterogeneous disease with diverse molecular profiles. The PAM50 gene signature is widely recognized as a standard for classifying breast cancer into intrinsic subtypes, enabling more personalized treatment…

Automated classification of histopathological whole-slide images (WSI) of breast tissue requires analysis at very high resolutions with a large contextual area. In this paper, we present context-aware stacked convolutional neural networks…

Computer Vision and Pattern Recognition · Computer Science 2017-05-11 Babak Ehteshami Bejnordi , Guido Zuidhof , Maschenka Balkenhol , Meyke Hermsen , Peter Bult , Bram van Ginneken , Nico Karssemeijer , Geert Litjens , Jeroen van der Laak

Gastric cancer ranks as the fifth most common and fourth most lethal cancer globally, with a dismal 5-year survival rate of approximately 20%. Despite extensive research on its pathobiology, the prognostic predictability remains inadequate,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Marco Usai , Andrea Loddo , Alessandra Perniciano , Maurizio Atzori , Cecilia Di Ruberto

Ovarian cancer remains a challenging malignancy to diagnose and manage, with prognosis heavily dependent on the stage at detection. Accurate grading and staging, primarily based on histopathological examination of biopsy tissue samples, are…

Medical Physics · Physics 2025-05-16 Ashmit K Mishra , Mousa Alrubayan , Prabhakar Pradhan

Breast cancer has the highest mortality among cancers in women. Computer-aided pathology to analyze microscopic histopathology images for diagnosis with an increasing number of breast cancer patients can bring the cost and delays of…

Computer Vision and Pattern Recognition · Computer Science 2020-03-03 Abhijeet Patil , Dipesh Tamboli , Swati Meena , Deepak Anand , Amit Sethi