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The COVID-19 pandemic has had and continues to have major impacts on planned and ongoing clinical trials. Its effects on trial data create multiple potential statistical issues. The scale of impact is unprecedented, but when viewed…

This paper presents the assessment of time-dependent national-level restrictions and control actions and their effects in fighting the COVID-19 pandemic. By analysing the transmission dynamics during the first wave of COVID-19 in the…

Populations and Evolution · Quantitative Biology 2021-02-04 Ton Duc Do , Meei Mei Gui , Kok Yew Ng

We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…

Populations and Evolution · Quantitative Biology 2021-08-17 Evangelos F. Magirou

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

As infectious disease outbreaks emerge, public health agencies often enact vaccination and social distancing measures to slow transmission. Their success depends on not only strategies and resources, but also public adherence. Individual…

Physics and Society · Physics 2018-08-20 José L. Herrera , Lauren Ancel Meyers

Frequent emergence of communicable diseases has been a major concern worldwide. Lack of sufficient resources to mitigate the disease-burden makes the situation even more challenging for lower-income countries. Hence, strategy development…

Populations and Evolution · Quantitative Biology 2023-02-03 Biplab Maity , Swarnendu Banerjee , Abhishek Senapati , Joydev Chattopadhyay

The pandemic caused by the novel Coronavirus SARS-CoV2 has been responsible for life threatening health complications, and extreme pressure on healthcare systems. While preventive and definite curative medical interventions are yet to…

Physics and Society · Physics 2020-09-09 Ankit Sharma , Shreyash Arya , Shashee Kumari , Arnab Chatterjee

Residential colleges and universities face unique challenges in providing in-person instruction during the COVID-19 pandemic. Administrators are currently faced with decisions about whether to open during the pandemic and what modifications…

Populations and Evolution · Quantitative Biology 2020-12-22 Philip T. Gressman , Jennifer R. Peck

The years 2020 and 2021 were characterized by the COVID-19 pandemic. The true impact of the pandemic on populations' health and life still has to be fully discerned. The main objective of this work is to discern the true impact of COVID-19…

Applications · Statistics 2025-10-17 Stefano Barone

India is one of the worst affected countries by the Covid-19 pandemic at present. We studied publicly available data of the Covid-19 patients in India and analyzed possible impacts of quarantine and social distancing within the stochastic…

Populations and Evolution · Quantitative Biology 2020-06-12 Athokpam Langlen Chanu , R. K. Brojen Singh

How much and when should we limit economic and social activity to ensure that the health-care system is not overwhelmed during an epidemic? We study a setting where ICU resources are constrained while suppression is costly (e.g., limiting…

Theoretical Economics · Economics 2020-05-05 Laurent Miclo , Daniel Spiro , Jörgen Weibull

The COVID-19 pandemic constitutes one of the largest threats in recent decades to the health and economic welfare of populations globally. In this paper, we analyze different types of policy measures designed to fight the spread of the…

General Economics · Economics 2020-11-03 Philipp Bach , Victor Chernozhukov , Martin Spindler

During the COVID-19 pandemic, safely implementing in-person indoor instruction was a high priority for universities nationwide. To support this effort at the University, we developed a mathematical model for estimating the risk of…

Applications · Statistics 2024-02-21 Brian Liu , Yujia Zhang , Shane G. Henderson , David B. Shmoys , Peter I. Frazier

The COVID-19 pandemic has, worldwide and up to December 2020, caused over 1.7 million deaths, and put the world's most advanced healthcare systems under heavy stress. In many countries, drastic restrictive measures adopted by political…

Signal Processing · Electrical Eng. & Systems 2023-01-18 Giovanni Soldi , Nicola Forti , Domenico Gaglione , Paolo Braca , Leonardo M. Millefiori , Stefano Marano , Peter Willett , Krishna Pattipati

As the COVID19 spreads across the world, prevention measures are becoming the essential weapons to combat the pandemic in the period of crisis. The lockdown measure is the most controversial one as it imposes an overwhelming impact on our…

Physics and Society · Physics 2021-02-12 Yuting Fu , Haitao Xiang , Hanqing Jin , Ning Wang

The Coronavirus Disease 2019 (COVID-19) pandemic has caused tremendous amount of deaths and a devastating impact on the economic development all over the world. Thus, it is paramount to control its further transmission, for which purpose it…

Applications · Statistics 2021-01-11 Quan-Lin Li , Chengliang Wang , Yiming Xu , Chi Zhang , Yanxia Chang , Xiaole Wu , Zhen-Ping Fan , Zhi-Guo Liu

We analyse 'stop-and-go' containment policies that produce infection cycles as periods of tight lockdowns are followed by periods of falling infection rates. The subsequent relaxation of containment measures allows cases to increase again…

Theoretical Economics · Economics 2021-11-22 Claudius Gros , Daniel Gros

The COVID-19 pandemic has forced policy makers to decree urgent confinements to stop a rapid and massive contagion. However, after that stage, societies are being forced to find an equilibrium between the need to reduce contagion rates and…

Since the outbreak of COVID-19, it has rapidly evolved into a sudden and major public health emergency globally. With the variants of COVID-19, the difficulty of pandemic control continues to increase, which has brought significant costs to…

Applications · Statistics 2022-08-26 Yufei Wang , Mingzhuang Hua , Xuewu Chen , Wendong Chen , Long Cheng

Accurate numbers are needed to understand and predict viral dynamics. Curation of high-quality literature values for the infectious period duration or household secondary attack rate, for example, is especially pressing currently because…

Other Quantitative Biology · Quantitative Biology 2020-07-10 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo