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Governments across the world are currently facing the task of selecting suitable intervention strategies to cope with the effects of the COVID-19 pandemic. This is a highly challenging task, since harsh measures may result in economic…

Optimization and Control · Mathematics 2021-01-19 Andreas Kasis , Stelios Timotheou , Nima Monshizadeh , Marios Polycarpou

The COVID-19 pandemic has posed a policy making crisis where efforts to slow down or end the pandemic conflict with economic priorities. This paper provides mathematical analysis of optimal disease control policies with idealized…

Optimization and Control · Mathematics 2021-02-16 Aaron Z. Palmer , Zelda B. Zabinsky , Shan Liu

In this study, we present a new epidemiological model, with contamination from confirmed and unreported. We also compute equilibria and study their stability without intervention strategies. Optimal control theory has proven to be a…

Populations and Evolution · Quantitative Biology 2020-08-14 Fulgence Mansal , Mouhamadou A. M. T. Baldé , Alpha O. Bah

Given multiple new COVID-19 variants are continuously emerging, non-pharmaceutical interventions are still primary control strategies to curb the further spread of coronavirus. However, implementing strict interventions over extended…

Populations and Evolution · Quantitative Biology 2022-03-01 Xiao Zhou , Xiaohu Zhang , Paolo Santi , Carlo Ratti

We analyze an approach to managing the COVID-19 pandemic without shutting down the economy while staying within the capacity of the healthcare system. We base our analysis on a detailed heterogeneous epidemiological model, which takes into…

Populations and Evolution · Quantitative Biology 2020-05-12 David Gershon , Alexander Lipton , Hagai Levine

The COVID-19 pandemic has plagued the world for months. The U.S. has taken measures to counter it. On a daily basis, newly confirmed cases have been reported. In the early days, these numbers showed an increasing trend. Recently, the…

Physics and Society · Physics 2020-05-21 Xiubin Bruce Wang , Chaolun Ma

We consider here an extended SIR model, including several features of the recent COVID-19 outbreak: in particular the infected and recovered individuals can either be detected (+) or undetected (-) and we also integrate an intensive care…

Populations and Evolution · Quantitative Biology 2020-05-25 Arthur Charpentier , Romuald Elie , Mathieu Laurière , Viet Chi Tran

Optimizing the impact on the economy of control strategies aiming at containing the spread of COVID-19 is a critical challenge. We use daily new case counts of COVID-19 patients reported by local health administrations from different…

Populations and Evolution · Quantitative Biology 2021-03-12 Afroza Shirin , Yen Ting Lin , Francesco Sorrentino

This article considers the minimization of the total number of infected individuals over the course of an epidemic in which the rate of infectious contacts can be reduced by time-dependent nonpharmaceutical interventions. The societal and…

Optimization and Control · Mathematics 2023-03-16 Tom Britton , Lasse Leskelä

The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

Physics and Society · Physics 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

In this paper we investigate feedback control techniques for the COVID-19 pandemic which are able to guarantee that the capacity of available intensive care unit beds is not exceeded. The control signal models the social distancing policies…

Optimization and Control · Mathematics 2021-10-29 Thomas Berger

Policymakers commonly employ non-pharmaceutical interventions to manage the scale and severity of pandemics. Of non-pharmaceutical interventions, social distancing policies -- designed to reduce person-to-person pathogenic spread -- have…

Physics and Society · Physics 2021-03-23 Demetris Avraam , Nick Obradovich , Niccoló Pescetelli , Manuel Cebrian , Alex Rutherford

The rapid spread of the Coronavirus (COVID-19) confronts policy makers with the problem of measuring the effectiveness of containment strategies, balancing public health considerations with the economic costs of social distancing measures.…

Physics and Society · Physics 2021-04-02 Claudius Gros , Roser Valenti , Lukas Schneider , Kilian Valenti , Daniel Gros

Several non-pharmaceutical interventions have been proposed to control the spread of the COVID-19 pandemic. On the large scale, these empirical solutions, often associated with extended and complete lockdowns, attempt to minimize the costs…

Physics and Society · Physics 2020-07-23 M. Serra , S. al-Mosleh , S. Ganga Prasath , V. Raju , S. Mantena , J. Chandra , S. Iams , L. Mahadevan

The COVID-19 pandemic began over two years ago, yet schools, businesses, and other organizations are still struggling to keep the risk of disease outbreak low while returning to (near) normal functionality. Observations from these past…

Populations and Evolution · Quantitative Biology 2022-02-02 Sarah C. Fay , Dalton J. Jones , Munther A. Dahleh , A. E. Hosoi

Social distancing has been the only effective way to contain the spread of an infectious disease prior to the availability of the pharmaceutical treatment. It can lower the infection rate of the disease at the economic cost. A pandemic…

Applications · Statistics 2020-12-07 Kexin Chen , Chi Seng Pun , Hoi Ying Wong

This paper studies if and to which extent COVID-19 epidemics can be controlled by authorities taking decisions on public health measures on the basis of daily reports of swab test results, active cases and total cases. A suitably simplified…

Physics and Society · Physics 2020-07-22 Francesco Casella

Pandemic control measures like lock-down, restrictions on restaurants and gatherings, social-distancing have shown to be effective in curtailing the spread of COVID-19. However, their sustained enforcement has negative economic effects. To…

A novel coronavirus disease has emerged (later named COVID-19) and caused the world to enter a new reality, with many direct and indirect factors influencing it. Some are human-controllable (e.g. interventional policies, mobility and the…

Machine Learning · Computer Science 2021-01-12 Haonan Wu , Rajarshi Banerjee , Indhumathi Venkatachalam , Daniel Percy-Hughes , Praveen Chougale

Given limited supply of approved vaccines and constrained medical resources, design of a vaccination strategy to control a pandemic is an economic problem. We use time-series and panel methods with real-world country-level data to estimate…

General Economics · Economics 2022-01-19 Dongwoo Kim , Young Jun Lee
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