Related papers: Planning interventions in a controlled pandemic: t…
Nowadays, the epidemic of COVID-19 in China is under control. However, the epidemic are developing rapidly around the world. Due to the normal migration of population, China is facing high risk from imported cases. The potential specific…
With a two-layer contact-dispersion model and data in China, we analyze the cost-effectiveness of three types of antiepidemic measures for COVID-19: regular epidemiological control, local social interaction control, and inter-city travel…
We formulate an optimal control problem to determine the lockdown policy to curb an epidemic where other control measures are not available yet. We present a unified framework to model the epidemic and economy that allows us to study the…
The adoption of containment measures to reduce the amplitude of the epidemic peak is a key aspect in tackling the rapid spread of an epidemic. Classical compartmental models must be modified and studied to correctly describe the effects of…
During a pandemic, there are conflicting demands arising from public health and economic cost. Lockdowns are a common way of containing infections, but they adversely affect the economy. We study the question of how to minimise the economic…
The sudden and rapid spread of the COVID_19 pandemic with its terrible consequences has put the management of governments and the various world institutions into a crisis. They have been subjected to a considerable economic effort to be…
At the time of writing, the ongoing COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), had already resulted in more than thirty-two million cases infected and more than one million deaths worldwide.…
COVID-19, a global pandemic of unprecedented scale, has had a profound impact on nations worldwide, resulting in the tragic loss of nearly 1.1 million lives in the United States and a staggering 7 million worldwide. In the absence of…
Motivated by the issue of COVID-19 mitigation, in this work we tackle the general problem of optimally controlling an epidemic outbreak of a communicable disease structured by time since exposure, by the aid of two types of control…
This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…
The novel coronavirus SARS-CoV-2 and resulting COVID-19 disease have had an unprecedented spread and continue to cause an increasing number of fatalities worldwide. While vaccines are still under development, social distancing, extensive…
The COVID-19 pandemic left its unique mark on the 21st century as one of the most significant disasters in history, triggering governments all over the world to respond with a wide range of interventions. However, these restrictions come…
Epidemics of infectious diseases posing a serious risk to human health have occurred throughout history. During recent epidemics there has been much debate about policy, including how and when to impose restrictions on behaviour.…
The novel COVID-19 pandemic is a current, major global health threat. Up till now, there is no fully approved pharmacological treatment or a vaccine. In this study, simple mathematical models were employed to examine the dynamics of…
While many efforts are currently devoted to vaccines development and administration, social distancing measures, including severe restrictions such as lockdowns, remain fundamental tools to contain the spread of COVID-19. A crucial point…
The emergence of coronavirus disease 2019 (COVID-19) in the United States has forced federal and local governments to implement containment measures. Moreover, the severity of the situation has sparked engagement by both the research and…
The mitigation of an infectious disease spreading has recently gained considerable attention from the research community. It may be obtained by adopting sanitary measurements social rules, together with an extensive vaccination campaign.…
We propose an epidemiological model that includes the mobility patterns of the individuals, in the spirit to those considered in (Barmak, 2011, 2016) and (Medus, 2011). We assume that people move around in a city of 120x120 blocks with 300…
During the COVID-19 pandemic of 2019/2020, authorities have used temporary ad-hoc policy measures, such as lockdowns and mass quarantines, to slow its transmission. However, the consequences of widespread use of these unprecedented measures…
I employ a simple mathematical model of an epidemic process to evaluate how four basic quantities: the reproduction number (R), the numbers of sensitive (S) and infectious individuals(I), and total community size (N) affect strategies to…