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The activity of biological cells is primarily based on chemical reactions and typically modeled as a reaction-diffusion system. Cells are, however, highly crowded with macromolecules, including a variety of molecular machines such as…

Biological Physics · Physics 2018-11-02 Yuichi Togashi

This work introduces a growable and modular neural network architecture that naturally avoids catastrophic forgetting and interference in continual reinforcement learning. The structure of each module allows the selective combination of…

Machine Learning · Computer Science 2025-06-19 Mikel Malagón , Josu Ceberio , Jose A. Lozano

Memory is often defined as the mental capacity of retaining information about facts, events, procedures and more generally about any type of previous experience. Memories are remembered as long as they influence our thoughts, feelings, and…

Neurons and Cognition · Quantitative Biology 2017-06-16 Stefano Fusi

Mutations in a microbial population can increase the frequency of a genotype not only by increasing its exponential growth rate, but also by decreasing its lag time or adjusting the yield (resource efficiency). The contribution of multiple…

Populations and Evolution · Quantitative Biology 2018-02-15 Michael Manhart , Bharat V. Adkar , Eugene I. Shakhnovich

The structure of the network can be described by motifs, which are subgraphs that often repeat themselves. In order to understand the structure of network motifs, it is of great importance to study subgraphs from the perspective of…

General Topology · Mathematics 2019-10-25 Ruize Gao , Ying Zhao

Existing studies comparing individual-based models of growing cell populations and their continuum counterparts have mainly focused on homogeneous populations, in which all cells have the same phenotypic characteristics. However,…

Populations and Evolution · Quantitative Biology 2022-06-06 Fiona R Macfarlane , Xinran Ruan , Tommaso Lorenzi

This paper investigates the problem of class-incremental object detection for agricultural applications where a model needs to learn new plant species and diseases incrementally without forgetting the previously learned ones. We adapt two…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Mathieu Pagé Fortin

A general 3D flow-and-transport model in porous media is derived using an axiomatic continuum-mechanics approach and implemented with the finite element method to simulate microbial enhanced oil recovery (MEOR) at core scale under…

Understanding how microorganisms navigate in complex environments is a central question in active matter and biological physics. Phototaxis - the ability to use light as a navigation cue - is a widespread strategy in motile microalgae to…

The most commonly developed inventory models are the classical economic order quantity model, is governed by the integer order differential equations. We want to come out from the traditional thought i.e. classical order inventory model…

Optimization and Control · Mathematics 2019-04-18 Rituparna Pakhira , Uttam Ghosh , Susmita Sarkar , Vishnu Narayan Mishra

Root systems can influence the dynamics of evapotranspiration of water out of a porous medium. The coupling of evapotranspiration remains a key aspect affecting overall root behavior. Predicting the evapotranspiration curve in the presence…

Soft Condensed Matter · Physics 2015-06-22 Cesare M. Cejas , Larry Hough , Jean-Christophe Castaing , Christian Fretigny , Remi Dreyfus

Collective rhythmic dynamics from neurons is vital for cognitive functions such as memory formation but how neurons self-organize to produce such activity is not well understood. Attractor-based models have been successfully implemented as…

Neurons and Cognition · Quantitative Biology 2013-03-22 Mark Niedringhaus , Xin Chen , Katherine Conant , Rhonda Dzakpasu

Since its foundations, more than one hundred years ago, the field of structural biology has strived to understand and analyze the properties of molecules and their interactions by studying the structure that they take in 3D space. However,…

Biomolecules · Quantitative Biology 2023-02-27 Gabriele Corso

We study the problem of maximizing a monotone submodular function with viability constraints. This problem originates from computational biology, where we are given a phylogenetic tree over a set of species and a directed graph, the…

Data Structures and Algorithms · Computer Science 2016-11-18 Wolfgang Dvořák , Monika Henzinger , David P. Williamson

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

Tissues and Organs · Quantitative Biology 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

Building models of natural language processing (NLP) is challenging in low-resource scenarios where only limited data are available. Optimization-based meta-learning algorithms achieve promising results in low-resource scenarios by adapting…

Computation and Language · Computer Science 2022-07-15 Yingxiu Zhao , Zhiliang Tian , Huaxiu Yao , Yinhe Zheng , Dongkyu Lee , Yiping Song , Jian Sun , Nevin L. Zhang

In this work, we consider a fully dynamic Biot model that includes memory effects due to evolving permeability. Time integrals are used to account for the change in structure. We propose an iterative splitting scheme for this model,…

Numerical Analysis · Mathematics 2024-07-24 Jakob S. Stokke , Morten Jakobsen , Kundan Kumar , Florin A. Radu

We investigate the computational limits of the memory retrieval dynamics of modern Hopfield models from the fine-grained complexity analysis. Our key contribution is the characterization of a phase transition behavior in the efficiency of…

Machine Learning · Computer Science 2024-06-04 Jerry Yao-Chieh Hu , Thomas Lin , Zhao Song , Han Liu

In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular…

Mathematical Physics · Physics 2010-11-09 Andrea Tosin

This paper presents a conceptual model describing the medium and long-term co-evolution of natural and socio-economic subsystems of Earth. An economy is viewed as an out-of-equilibrium dissipative structure that can only be maintained with…

General Economics · Economics 2022-05-09 Éric Herbert , and Gael Giraud , Aurélie Louis-Napoléon , Christophe Goupil