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Automated cervical nucleus segmentation based on deep learning can effectively improve the quantitative analysis of cervical cancer. However, accurate nuclei segmentation is still challenging. The classic U-net has not achieved satisfactory…

Image and Video Processing · Electrical Eng. & Systems 2019-11-13 Jie Zhao , Lei Dai , Mo Zhang , Fei Yu , Meng Li , Hongfeng Li , Wenjia Wang , Li Zhang

Numerous deep learning based methods have been developed for nuclei segmentation for H&E images and have achieved close to human performance. However, direct application of such methods to another modality of images, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-08-15 Roger Trullo , Quoc-Anh Bui , Qi Tang , Reza Olfati-Saber

Object segmentation is an important step in the workflow of computational pathology. Deep learning based models generally require large amount of labeled data for precise and reliable prediction. However, collecting labeled data is…

Computer Vision and Pattern Recognition · Computer Science 2020-07-08 Navid Alemi Koohbanani , Mostafa Jahanifar , Neda Zamani Tajadin , Nasir Rajpoot

Gigapixel medical images provide massive data, both morphological textures and spatial information, to be mined. Due to the large data scale in histology, deep learning methods play an increasingly significant role as feature extractors.…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Yiqing Shen , Bingxin Zhou , Xinye Xiong , Ruitian Gao , Yu Guang Wang

Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre

The development of medical image segmentation using deep learning can significantly support doctors' diagnoses. Deep learning needs large amounts of data for training, which also requires data augmentation to extend diversity for preventing…

Image and Video Processing · Electrical Eng. & Systems 2023-04-27 Xiaoqing Liu , Kenji Ono , Ryoma Bise

We present MosaicFusion, a simple yet effective diffusion-based data augmentation approach for large vocabulary instance segmentation. Our method is training-free and does not rely on any label supervision. Two key designs enable us to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Jiahao Xie , Wei Li , Xiangtai Li , Ziwei Liu , Yew Soon Ong , Chen Change Loy

Along with predictive performance and runtime speed, reliability is a key requirement for real-world semantic segmentation. Reliability encompasses robustness, predictive uncertainty and reduced bias. To improve reliability, we introduce…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Gianni Franchi , Nacim Belkhir , Mai Lan Ha , Yufei Hu , Andrei Bursuc , Volker Blanz , Angela Yao

Copy-Paste has proven to be a very effective data augmentation for instance segmentation which can improve the generalization of the model. We used a task-specific Copy-Paste data augmentation method to achieve good performance on the…

Computer Vision and Pattern Recognition · Computer Science 2021-10-04 Jahongir Yunusov , Shohruh Rakhmatov , Abdulaziz Namozov , Abdulaziz Gaybulayev , Tae-Hyong Kim

Generating realistic tissue images with annotations is a challenging task that is important in many computational histopathology applications. Synthetically generated images and annotations are valuable for training and evaluating…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Srijay Deshpande , Fayyaz Minhas , Nasir Rajpoot

Highly clumped nuclei clusters captured in fluorescence in situ hybridization microscopy images are common histology entities under investigations in a wide spectrum of tissue-related biomedical investigations. Due to their large scale in…

Computer Vision and Pattern Recognition · Computer Science 2018-08-15 Xiaoyuan Guo , Hanyi Yu , Blair Rossetti , George Teodoro , Daniel Brat , Jun Kong

Deep learning-based nuclei segmentation and classification in pathology images typically rely on large-scale pixel-level manual annotations, which are costly and difficult to obtain across diverse tissues and staining conditions. To address…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Kazuya Nishimura , Ryoma Bise , Haruka Hirose , Yasuhiro Kojima

Thin and elongated filamentous structures, such as microtubules and actin filaments, often play important roles in biological systems. Segmenting these filaments in biological images is a fundamental step for quantitative analysis. Recent…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Yi Liu , Yichi Zhang

Accurate segmentation of 3-D cell nuclei in microscopy images is essential for the study of nuclear organization, gene expression, and cell morphodynamics. Current image segmentation methods are challenged by the complexity and variability…

Image and Video Processing · Electrical Eng. & Systems 2022-03-18 Sundaresh Ram , Jeffrey J. Rodriguez

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

Image and Video Processing · Electrical Eng. & Systems 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

Interactive graph-based segmentation methods partition an image into foreground and background regions with the aid of user inputs. However, existing approaches often suffer from high computational costs, sensitivity to user interactions,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Kaustubh Shivshankar Shejole , Gaurav Mishra

Automatic brain tumor segmentation from Magnetic Resonance Imaging (MRI) data plays an important role in assessing tumor response to therapy and personalized treatment stratification.Manual segmentation is tedious and…

Image and Video Processing · Electrical Eng. & Systems 2021-11-29 Hadas Ben-Atya , Ori Rajchert , Liran Goshen , Moti Freiman

Unsupervised instance segmentation aims to segment distinct object instances in an image without relying on human-labeled data. This field has recently seen significant advancements, partly due to the strong local correspondences afforded…

Computer Vision and Pattern Recognition · Computer Science 2024-09-30 Dylan Li , Gyungin Shin

Instance segmentation of nuclei and glands in the histology images is an important step in computational pathology workflow for cancer diagnosis, treatment planning and survival analysis. With the advent of modern hardware, the recent…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Esha Sadia Nasir , Arshi Perviaz , Muhammad Moazam Fraz

In computer vision, it is well-known that a lack of data diversity will impair model performance. In this study, we address the challenges of enhancing the dataset diversity problem in order to benefit various downstream tasks such as…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Yuhang Li , Xin Dong , Chen Chen , Weiming Zhuang , Lingjuan Lyu
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