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We present a new instance segmentation approach tailored to biological images, where instances may correspond to individual cells, organisms or plant parts. Unlike instance segmentation for user photographs or road scenes, in biological…

Computer Vision and Pattern Recognition · Computer Science 2020-04-24 Victor Kulikov , Victor Lempitsky

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Collecting pixel-level labels for medical datasets can be a laborious and expensive process, and enhancing segmentation performance with a scarcity of labeled data is a crucial challenge. This work introduces AugPaint, a data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xinrong Hu , Yiyu Shi

Data augmentation has become a de facto component of deep learning-based medical image segmentation methods. Most data augmentation techniques used in medical imaging focus on spatial and intensity transformations to improve the diversity…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Berke Doga Basaran , Weitong Zhang , Mengyun Qiao , Bernhard Kainz , Paul M. Matthews , Wenjia Bai

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Generative Adversarial Networks (GANs) typically suffer from overfitting when limited training data is available. To facilitate GAN training, current methods propose to use data-specific augmentation techniques. Despite the effectiveness,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Jie Cao , Mandi Luo , Junchi Yu , Ming-Hsuan Yang , Ran He

Segmentation and accurate localization of nuclei in histopathological images is a very challenging problem, with most existing approaches adopting a supervised strategy. These methods usually rely on manual annotations that require a lot of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-17 Mihir Sahasrabudhe , Stergios Christodoulidis , Roberto Salgado , Stefan Michiels , Sherene Loi , Fabrice André , Nikos Paragios , Maria Vakalopoulou

Existing deep learning-based approaches for histopathology image analysis require large annotated training sets to achieve good performance; but annotating histopathology images is slow and resource-intensive. Conditional generative…

Image and Video Processing · Electrical Eng. & Systems 2021-10-29 Sujata Butte , Haotian Wang , Min Xian , Aleksandar Vakanski

High-quality and challenging event stream datasets play an important role in the design of an efficient event-driven mechanism that mimics the brain. Although event cameras can provide high dynamic range and low-energy event stream data,…

Neural and Evolutionary Computing · Computer Science 2022-05-25 Guobin Shen , Dongcheng Zhao , Yi Zeng

Deep learning models have demonstrated remarkable performance across various computer vision tasks, yet their vulnerability to distribution shifts remains a critical challenge. Despite sophisticated neural network architectures, existing…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Hafiz Mughees Ahmad , Dario Morle , Afshin Rahimi

High-resolution microscopy images of tissue specimens provide detailed information about the morphology of normal and diseased tissue. Image analysis of tissue morphology can help cancer researchers develop a better understanding of cancer…

Advances in fluorescence microscopy enable acquisition of 3D image volumes with better image quality and deeper penetration into tissue. Segmentation is a required step to characterize and analyze biological structures in the images and…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Chichen Fu , Soonam Lee , David Joon Ho , Shuo Han , Paul Salama , Kenneth W. Dunn , Edward J. Delp

The classification of glomerular lesions is a routine and essential task in renal pathology. Recently, machine learning approaches, especially deep learning algorithms, have been used to perform computer-aided lesion characterization of…

Quantitative Methods · Quantitative Biology 2021-01-20 Yuzhe Lu , Haichun Yang , Zheyu Zhu , Ruining Deng , Agnes B. Fogo , Yuankai Huo

Tumor segmentation plays a critical role in histopathology, but it requires costly, fine-grained image-mask pairs annotated by pathologists. Thus, synthesizing histopathology data to expand the dataset is highly desirable. Previous works…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Hong Liu , Haosen Yang , Evi M. C. Huijben , Mark Schuiveling , Ruisheng Su , Josien P. W. Pluim , Mitko Veta

Automatic segmentation of neuronal topology is critical for handling large scale neuroimaging data, as it can greatly accelerate neuron annotation and analysis. However, the intricate morphology of neuronal branches and the occlusions among…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Huayu Fu , Jiamin Li , Haozhi Qu , Xiaolin Hu , Zengcai Guo

Modern histopathological image analysis relies on the segmentation of cell structures to derive quantitative metrics required in biomedical research and clinical diagnostics. State-of-the-art deep learning approaches predominantly apply…

Image and Video Processing · Electrical Eng. & Systems 2022-01-12 Yoav Alon , Huiyu Zhou

Augmentation for dense prediction typically relies on either sample mixing or generative synthesis. Mixing improves robustness but misaligned masks yield soft label ambiguity. Diffusion synthesis increases apparent diversity but, when…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Pengyu Jie , Wanquan Liu , Rui He , Yihui Wen , Deyu Meng , Chenqiang Gao

Labeling semantic segmentation datasets is a costly and laborious process if compared with tasks like image classification and object detection. This is especially true for remote sensing applications that not only work with extremely high…

Computer Vision and Pattern Recognition · Computer Science 2021-08-27 Matheus Barros Pereira , Jefersson Alex dos Santos

Joint synthesis of images and segmentation masks with generative adversarial networks (GANs) is promising to reduce the effort needed for collecting image data with pixel-wise annotations. However, to learn high-fidelity image-mask…

Computer Vision and Pattern Recognition · Computer Science 2022-09-19 Vadim Sushko , Dan Zhang , Juergen Gall , Anna Khoreva

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu