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Nuclei instance segmentation is an essential task in pathology image analysis, serving as the foundation for many downstream applications. The release of several public datasets has significantly advanced research in this area, yet many…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Jin Tae Kwak

Nuclei segmentation is a fundamental but challenging task in the quantitative analysis of histopathology images. Although fully-supervised deep learning-based methods have made significant progress, a large number of labeled images are…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Xinyi Yu , Guanbin Li , Wei Lou , Siqi Liu , Xiang Wan , Yan Chen , Haofeng Li

Nuclei segmentation and classification is a significant process in pathology image analysis. Deep learning-based approaches have greatly contributed to the higher accuracy of this task. However, those approaches suffer from the imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Hyun-Jic Oh , Won-Ki Jeong

An automated segmentation and classification of nuclei is an essential task in digital pathology. The current deep learning-based approaches require a vast amount of annotated datasets by pathologists. However, the existing datasets are…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Tan Nhu Nhat Doan , Kyungeun Kim , Boram Song , Jin Tae Kwak

In computational pathology, researchers often face challenges due to the scarcity of labeled pathology datasets. Data augmentation emerges as a crucial technique to mitigate this limitation. In this study, we introduce an efficient data…

Computer Vision and Pattern Recognition · Computer Science 2025-02-25 Jiamu Wang , Jin Tae Kwak

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

Data mixing augmentation has proved effective in training deep models. Recent methods mix labels mainly based on the mixture proportion of image pixels. As the main discriminative information of a fine-grained image usually resides in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-10 Shaoli Huang , Xinchao Wang , Dacheng Tao

In this study, we propose a novel data augmentation method that introduces the concept of CutMix into the generation process of diffusion models, thereby exploiting both the ability of diffusion models to generate natural and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Shumpei Takezaki , Ryoma Bise , Shinnosuke Matsuo

In medical image diagnosis, pathology image analysis using semantic segmentation becomes important for efficient screening as a field of digital pathology. The spatial augmentation is ordinary used for semantic segmentation. Tumor images…

Machine Learning · Computer Science 2021-03-04 Takato Yasuno

In pathology image analysis, obtaining and maintaining high-quality annotated samples is an extremely labor-intensive task. To overcome this challenge, mixing-based methods have emerged as effective alternatives to traditional preprocessing…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Tianyi Zhang , Zhiling Yan , Chunhui Li , Nan Ying , Yanli Lei , Yunlu Feng , Yu Zhao , Guanglei Zhang

Due to the high cost of annotation or the rarity of some diseases, medical image segmentation is often limited by data scarcity and the resulting overfitting problem. Self-supervised learning and semi-supervised learning can mitigate the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Danyang Sun , Fadi Dornaika , Nagore Barrena

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Histopathology image synthesis aims to address the data shortage issue in training deep learning approaches for accurate cancer detection. However, existing methods struggle to produce realistic images that have accurate nuclei boundaries…

Image and Video Processing · Electrical Eng. & Systems 2023-01-25 Sujata Butte , Haotian Wang , Aleksandar Vakanski , Min Xian

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Segmentation of nuclei regions from histological images enables morphometric analysis of nuclei structures, which in turn helps in the detection and diagnosis of diseases under consideration. To develop a nuclei segmentation algorithm,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

Data augmentation is widely used to enhance generalization in visual classification tasks. However, traditional methods struggle when source and target domains differ, as in domain adaptation, due to their inability to address domain gaps.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Khawar Islam , Muhammad Zaigham Zaheer , Arif Mahmood , Karthik Nandakumar , Naveed Akhtar

Convolutional neural networks (CNN) are capable of learning robust representation with different regularization methods and activations as convolutional layers are spatially correlated. Based on this property, a large variety of regional…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Devesh Walawalkar , Zhiqiang Shen , Zechun Liu , Marios Savvides

Nuclear instance segmentation plays a vital role in disease diagnosis within digital pathology. However, limited labeled data in pathological images restricts the overall performance of nuclear instance segmentation. To tackle this…

Image and Video Processing · Electrical Eng. & Systems 2025-04-03 Lirui Qi , Hongliang He , Tong Wang , Siwei Feng , Guohong Fu

Scarcity of annotated data, particularly for rare or atypical morphologies, present significant challenges for cell and nuclei segmentation in computational pathology. While manual annotation is labor-intensive and costly, synthetic data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Dominik Winter , Mai Bui , Monica Azqueta Gavaldon , Nicolas Triltsch , Marco Rosati , Nicolas Brieu

In this paper, we propose a novel data augmentation technique called GenMix, which combines generative and mixture approaches to leverage the strengths of both methods. While generative models excel at creating new data patterns, they face…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Hansang Lee , Haeil Lee , Helen Hong
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