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Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve…

Computer Vision and Pattern Recognition · Computer Science 2018-02-07 Jason Causey , Junyu Zhang , Shiqian Ma , Bo Jiang , Jake Qualls , David G. Politte , Fred Prior , Shuzhong Zhang , Xiuzhen Huang

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Spiculations are important predictors of lung cancer malignancy, which are spikes on the surface of the pulmonary nodules. In this study, we proposed an interpretable and parameter-free technique to quantify the spiculation using area…

Computer Vision and Pattern Recognition · Computer Science 2020-10-16 Wookjin Choi , Saad Nadeem , Sadegh Riyahi , Joseph O. Deasy , Allen Tannenbaum , Wei Lu

Recently, Computer-Aided Diagnosis (CAD) systems have emerged as indispensable tools in clinical diagnostic workflows, significantly alleviating the burden on radiologists. Nevertheless, despite their integration into clinical settings, CAD…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Hongyu Chen , Zaiyong Zhang , Nan Yang , Haorang Zhang , Lifu Ma , Wenjing Xu , Huixiang Zhi

We present a hybrid algorithm to estimate lung nodule malignancy that combines imaging biomarkers from Radiologist's annotation with image classification of CT scans. Our algorithm employs a 3D Convolutional Neural Network (CNN) as well as…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Kushal Mehta , Arshita Jain , Jayalakshmi Mangalagiri , Sumeet Menon , Phuong Nguyen , David R. Chapman

Background and Objective:Computer-aided diagnosis (CAD) systems promote diagnosis effectiveness and alleviate pressure of radiologists. A CAD system for lung cancer diagnosis includes nodule candidate detection and nodule malignancy…

Image and Video Processing · Electrical Eng. & Systems 2022-01-17 Shaohua Zheng , Zhiqiang Shen , Chenhao Peia , Wangbin Ding , Haojin Lin , Jiepeng Zheng , Lin Pan , Bin Zheng , Liqin Huang

Pathologies systematically induce morphological changes, thus providing a major but yet insufficiently quantified source of observables for diagnosis. The study develops a predictive model of the pathological states based on morphological…

Automatic diagnosing lung cancer from Computed Tomography (CT) scans involves two steps: detect all suspicious lesions (pulmonary nodules) and evaluate the whole-lung/pulmonary malignancy. Currently, there are many studies about the first…

Computer Vision and Pattern Recognition · Computer Science 2019-02-04 Fangzhou Liao , Ming Liang , Zhe Li , Xiaolin Hu , Sen Song

The early identification of malignant pulmonary nodules is critical for better lung cancer prognosis and less invasive chemo or radio therapies. Nodule malignancy assessment done by radiologists is extremely useful for planning a preventive…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Ilaria Bonavita , Xavier Rafael-Palou , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel A. González Ballester

The LIDC-IDRI database is the most popular benchmark for lung cancer prediction. However, with subjective assessment from radiologists, nodules in LIDC may have entirely different malignancy annotations from the pathological ground truth,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Hanxiao Zhang , Xiao Gu , Minghui Zhang , Weihao Yu , Liang Chen , Zhexin Wang , Feng Yao , Yun Gu , Guang-Zhong Yang

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Chenglong Wang , Yun Liu , Fen Wang , Chengxiu Zhang , Yida Wang , Mei Yuan , Guang Yang

Lung cancer is the leading cause of cancer-related mortality worldwide. Lung cancer screening (LCS) using annual low-dose computed tomography (CT) scanning has been proven to significantly reduce lung cancer mortality by detecting cancerous…

Lung nodule malignancy prediction is an essential step in the early diagnosis of lung cancer. Besides the difficulties commonly discussed, the challenges of this task also come from the ambiguous labels provided by annotators, since deep…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Zehui Liao , Yutong Xie , Shishuai Hu , Yong Xia

Recently, intelligent analysis of lung nodules with the assistant of computer aided detection (CAD) techniques can improve the accuracy rate of lung cancer diagnosis. However, existing CAD systems and pulmonary datasets mainly focus on…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Haoran Zhang , Mingju Shao , Hongyu Chen , Huihui Huang , Yanjie Zhong , Changlei Zhang , Bin Wang , Penghui Gao

Lung nodule malignancy prediction has been enhanced by advanced deep-learning techniques and effective tricks. Nevertheless, current methods are mainly trained with cross-entropy loss using one-hot categorical labels, which results in…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Yiming Lei , Zilong Li , Yan Shen , Junping Zhang , Hongming Shan

Early diagnosis of lung cancer is a key intervention for the treatment of lung cancer computer aided diagnosis (CAD) can play a crucial role. However, most published CAD methods treat lung cancer diagnosis as a lung nodule classification…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Junhua Chen , Haiyan Zeng , Chong Zhang , Zhenwei Shi , Andre Dekker , Leonard Wee , Inigo Bermejo

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

Lung cancer remains one of the most common and deadliest forms of cancer worldwide. The likelihood of successful treatment depends strongly on the stage at which the disease is diagnosed. Therefore, early detection of lung cancer represents…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Volodymyr Sydorskyi

Lung cancer accounts for the highest number of cancer deaths globally. Early diagnosis of lung nodules is very important to reduce the mortality rate of patients by improving the diagnosis and treatment of lung cancer. This work proposes an…

Computer Vision and Pattern Recognition · Computer Science 2016-05-27 Tizita Nesibu Shewaye , Alhayat Ali Mekonnen

Lung cancer is the leading cause for cancer related deaths. As such, there is an urgent need for a streamlined process that can allow radiologists to provide diagnosis with greater efficiency and accuracy. A powerful tool to do this is…

Computer Vision and Pattern Recognition · Computer Science 2017-03-29 Devinder Kumar , Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong
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