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In this work, we present a fully automated lung CT cancer diagnosis system, DeepLung. DeepLung contains two parts, nodule detection and classification. Considering the 3D nature of lung CT data, two 3D networks are designed for the nodule…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie

Lung cancer follow-up is a complex, error prone, and time consuming task for clinical radiologists. Several lung CT scan images taken at different time points of a given patient need to be individually inspected, looking for possible…

Image and Video Processing · Electrical Eng. & Systems 2019-12-24 Xavier Rafael-Palou , Anton Aubanell , Ilaria Bonavita , Mario Ceresa , Gemma Piella , Vicent Ribas , Miguel Ángel González Ballester

Lung cancer remains the leading cause of cancer-related mortality worldwide, with survival strongly dependent on early detection. Standard-dose computed tomography (CT) screening using the Lung Imaging Reporting and Data System (Lung-RADS)…

Objective: Lung cancer is the leading cause of cancer-related death worldwide. Computer-aided diagnosis (CAD) systems have shown significant promise in recent years for facilitating the effective detection and classification of abnormal…

Computer Vision and Pattern Recognition · Computer Science 2019-01-16 Vignesh Sankar , Devinder Kumar , David A. Clausi , Graham W. Taylor , Alexander Wong

We present crowdsourcing as an additional modality to aid radiologists in the diagnosis of lung cancer from clinical chest computed tomography (CT) scans. More specifically, a complete workflow is introduced which can help maximize the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-19 Saeed Boorboor , Saad Nadeem , Ji Hwan Park , Kevin Baker , Arie Kaufman

The segmentation module which precisely outlines the nodules is a crucial step in a computer-aided diagnosis(CAD) system. The most challenging part of such a module is how to achieve high accuracy of the segmentation, especially for the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Xinliang Fu , Jiayin Zheng , Juanyun Mai , Yanbo Shao , Minghao Wang , Linyu Li , Zhaoqi Diao , Yulong Chen , Jianyu Xiao , Jian You , Airu Yin , Yang Yang , Xiangcheng Qiu , Jinsheng Tao , Bo Wang , Hua Ji

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Evaluation of artificial intelligence (AI) models for low-dose CT lung cancer screening is limited by heterogeneous datasets, annotation standards, and evaluation protocols, making performance difficult to compare and translate across…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Fakrul Islam Tushar , Avivah Wang , Lavsen Dahal , Ehsan Samei , Michael R. Harowicz , Jayashree Kalpathy-Cramer , Kyle J. Lafata , Tina D. Tailor , Cynthia Rudin , Joseph Y. Lo

Follow-up serves an important role in the management of pulmonary nodules for lung cancer. Imaging diagnostic guidelines with expert consensus have been made to help radiologists make clinical decision for each patient. However, tumor…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Yamin Li , Jiancheng Yang , Yi Xu , Jingwei Xu , Xiaodan Ye , Guangyu Tao , Xueqian Xie , Guixue Liu

Accurate segmentation and classification of brain tumors from Magnetic Resonance Imaging (MRI) remain key challenges in medical image analysis, primarily due to the lack of high-quality, balanced, and diverse datasets with expert…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Amirreza Fateh , Yasin Rezvani , Sara Moayedi , Sadjad Rezvani , Fatemeh Fateh , Mansoor Fateh , Vahid Abolghasemi

Objective: Lung cancer is a leading cause of cancer-related mortality worldwide, primarily due to delayed diagnosis and poor early detection. This study aims to develop a computer-aided diagnosis (CAD) system that leverages large…

Image and Video Processing · Electrical Eng. & Systems 2025-09-16 Hafza Eman , Furqan Shaukat , Muhammad Hamza Zafar , Syed Muhammad Anwar

Current LLMs for creating fully-structured reports face the challenges of formatting errors, content hallucinations, and privacy leakage issues when uploading data to external servers.We aim to develop an open-source, accurate LLM for…

Artificial Intelligence · Computer Science 2025-09-29 Chuang Niu , Md Sayed Tanveer , Md Zabirul Islam , Parisa Kaviani , Qing Lyu , Mannudeep K. Kalra , Christopher T. Whitlow , Ge Wang

Background and Objective: Early detection of lung cancer is crucial as it has high mortality rate with patients commonly present with the disease at stage 3 and above. There are only relatively few methods that simultaneously detect and…

Image and Video Processing · Electrical Eng. & Systems 2020-12-18 Kelvin Shak , Mundher Al-Shabi , Andrea Liew , Boon Leong Lan , Wai Yee Chan , Kwan Hoong Ng , Maxine Tan

Purpose: The lung nodules localization in CT scan images is the most difficult task due to the complexity of the arbitrariness of shape, size, and texture of lung nodules. This is a challenge to be faced when coming to developing different…

Image and Video Processing · Electrical Eng. & Systems 2023-01-06 Haytham Al Ewaidat , Youness El Brag

Risk stratification of lung nodules is a task of primary importance in lung cancer diagnosis. Any improvement in robust and accurate nodule characterization can assist in identifying cancer stage, prognosis, and improving treatment…

Computer Vision and Pattern Recognition · Computer Science 2017-10-27 Sarfaraz Hussein , Kunlin Cao , Qi Song , Ulas Bagci

Lung cancer is one of the most deadly diseases in the world. Detecting such tumors at an early stage can be a tedious task. Existing deep learning architecture for lung nodule identification used complex architecture with large number of…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Shah B. Shrey , Lukman Hakim , Muthusubash Kavitha , Hae Won Kim , Takio Kurita

Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Sarfaraz Hussein , Robert Gillies , Kunlin Cao , Qi Song , Ulas Bagci

Lung cancer is the leading cause of cancer death and early diagnosis is associated with a positive prognosis. Chest X-ray (CXR) provides an inexpensive imaging mode for lung cancer diagnosis. Suspicious nodules are difficult to distinguish…

Image and Video Processing · Electrical Eng. & Systems 2023-07-14 Michael James Horry , Subrata Chakraborty , Biswajeet Pradhan , Manoranjan Paul , Jing Zhu , Prabal Datta Barua , U. Rajendra Acharya , Fang Chen , Jianlong Zhou

The accurate classification of benign and malignant pulmonary nodules in CT scans is critical for early lung cancer screening, yet remains challenging due to the multi-scale and heterogeneous nature of pulmonary nodules. While deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Jinyue Li , Yuzhou Yu , Jingjing Yang , Meng Fu , Yani Zhang , Shuyao He , Dianlong Ge , Xin Ning , Yannan Chu , Qiankun Li

An accurate segmentation of lung nodules in computed tomography (CT) images is critical to lung cancer analysis and diagnosis. However, due to the variety of lung nodules and the similarity of visual characteristics between nodules and…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Haichao Cao , Hong Liu , Enmin Song , Chih-Cheng Hung , Guangzhi Ma , Xiangyang Xu , Renchao Jin , Jianguo Lu